D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 121 Citations 52,924 681 World Ranking 2026 National Ranking 1181

Research.com Recognitions

Awards & Achievements

2019 - Fellow, National Academy of Inventors

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Cancer

John P. Cooke spends much of his time researching Internal medicine, Endocrinology, Nitric oxide, Endothelium and Vasodilation. As part of his studies on Internal medicine, John P. Cooke often connects relevant subjects like Asymmetric dimethylarginine. His research in Endocrinology intersects with topics in Platelet and Antagonist.

The Nitric oxide study combines topics in areas such as Cell culture, Arginine, Pharmacology and Biochemistry. John P. Cooke combines subjects such as Endothelial stem cell, Angiogenesis, Biophysics and Immunology, Monocyte with his study of Endothelium. His work carried out in the field of Vasodilation brings together such families of science as Artery, Methacholine, Anatomy, Forearm and Vascular disease.

His most cited work include:

  • Asymmetric Dimethylarginine (ADMA): A Novel Risk Factor for Endothelial Dysfunction Its Role in Hypercholesterolemia (1089 citations)
  • Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. (928 citations)
  • L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans. (805 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Internal medicine, Endocrinology, Nitric oxide, Endothelium and Cell biology. His Internal medicine research is multidisciplinary, relying on both Asymmetric dimethylarginine and Cardiology. His Nitric oxide research includes elements of Arginine, Pharmacology and Endogeny, Biochemistry.

Endothelium is often connected to Monocyte in his work. His Cell biology study combines topics in areas such as Endothelial stem cell, Reprogramming, Immunology, Induced pluripotent stem cell and Innate immune system. In his study, Nicotine, Vascular endothelial growth factor and Pathology is inextricably linked to Angiogenesis, which falls within the broad field of Endothelial stem cell.

He most often published in these fields:

  • Internal medicine (39.56%)
  • Endocrinology (22.81%)
  • Nitric oxide (17.63%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cell biology (16.00%)
  • Internal medicine (39.56%)
  • Cardiology (14.22%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Internal medicine, Cardiology, Cancer research and Angiogenesis. John P. Cooke has included themes like Endothelial stem cell, Innate immune system, Transcription factor and Induced pluripotent stem cell in his Cell biology study. John P. Cooke has researched Innate immune system in several fields, including Epigenetics, Nitric oxide and Somatic cell.

John P. Cooke interconnects Chromatin and Endothelium in the investigation of issues within Transcription factor. His Internal medicine research includes themes of Asymmetric dimethylarginine, Endocrinology and Mesenchymal stem cell. His biological study spans a wide range of topics, including Paracrine signalling, LMO2, Immunology and Pathology.

Between 2014 and 2021, his most popular works were:

  • Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population (207 citations)
  • Modulating the Vascular Response to Limb Ischemia: Angiogenic and Cell Therapies (119 citations)
  • Transdifferentiation of Human Fibroblasts to Endothelial Cells Role of Innate Immunity (92 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Cancer

His primary areas of study are Cell biology, Inflammation, Cancer research, Angiogenesis and Pathology. His studies deal with areas such as Chromatin, Innate immune system, Transcription factor and Endothelium as well as Cell biology. His studies in Endothelium integrate themes in fields like Regeneration and Immunity.

The study incorporates disciplines such as Vascular endothelial growth factor C and Paracrine signalling in addition to Pathology. His work in the fields of Nitric oxide synthase and Nitrosylation overlaps with other areas such as S-Nitrosylation. John P. Cooke integrates many fields in his works, including Internal medicine and GERD.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Asymmetric Dimethylarginine (ADMA): A Novel Risk Factor for Endothelial Dysfunction Its Role in Hypercholesterolemia

Rainer H. Böger;Stefanie M. Bode-Böger;Andrzej Szuba;Philip S. Tsao.
Circulation (1998)

1593 Citations

Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans.

Mark A. Creager;John P. Cooke;Michael E. Mendelsohn;Shelly J. Gallagher.
Journal of Clinical Investigation (1990)

1352 Citations

Endogenous Nitric Oxide Synthase Inhibitor A Novel Marker of Atherosclerosis

Hiroshi Miyazaki;Hidehiro Matsuoka;John P. Cooke;Michiaki Usui.
Circulation (1999)

1088 Citations

L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.

Mark A. Creager;Shelly J. Gallagher;Xavier J. Girerd;Sharon M. Coleman.
Journal of Clinical Investigation (1992)

1038 Citations

Gene therapy inhibiting neointimal vascular lesion: In vivo transfer of endothelial cell nitric oxide synthase gene

H. E. Von Der Leyen;G. H. Gibbons;R. Morishita;N. P. Lewis.
Proceedings of the National Academy of Sciences of the United States of America (1995)

1000 Citations

Nitric oxide synthase: role in the genesis of vascular disease.

John P. Cooke;Victor J. Dzau.
Annual Review of Medicine (1997)

978 Citations

Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis

Christopher Heeschen;James J. Jang;Michael Weis;Anjali Pathak.
Nature Medicine (2001)

963 Citations

Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit.

John P. Cooke;Alan H. Singer;Philip Tsao;Pauline Zera.
Journal of Clinical Investigation (1992)

910 Citations

Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase.

Akira Ito;Philip S. Tsao;Shanthi Adimoolam;Masumi Kimoto.
Circulation (1999)

909 Citations

Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase.

Ken Y. Lin;Akira Ito;Tomoko Asagami;Philip S. Tsao.
Circulation (2002)

905 Citations

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