D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 136 Citations 71,320 630 World Ranking 786 National Ranking 474

Research.com Recognitions

Awards & Achievements

2014 - Fellow of the American Association for the Advancement of Science (AAAS)

2013 - Fellow of the American Academy of Arts and Sciences

2006 - Member of the National Academy of Medicine (NAM)

2004 - Distinguished Scientist Award, American Heart Association

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

Joseph Loscalzo mainly focuses on Internal medicine, Biochemistry, Nitric oxide, Endocrinology and Platelet. His Internal medicine research incorporates themes from Immunology and Cardiology. His study looks at the relationship between Biochemistry and topics such as Cell biology, which overlap with Hypoxia, Regulation of gene expression, Hypoxia-inducible factors and Transcription factor.

Joseph Loscalzo has researched Nitric oxide in several fields, including Reactive oxygen species, Thiol, Pharmacology and Biological activity. His Platelet research focuses on subjects like Fibrinogen, which are linked to Tissue plasminogen activator. His Endothelium research also works with subjects such as

  • Vascular disease and related Pathogenesis and Fibrinolysis,
  • Pathology most often made with reference to Endothelial stem cell.

His most cited work include:

  • Harrison's Principles of Internal Medicine (12175 citations)
  • Network Medicine: A Network-Based Approach to Human Disease (2874 citations)
  • Biochemistry of nitric oxide and its redox-activated forms (2385 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Internal medicine, Endocrinology, Nitric oxide, Biochemistry and Cardiology. His studies in Endothelium, Platelet, Pulmonary hypertension, Endothelial dysfunction and Homocysteine are all subfields of Internal medicine research. His work in Aldosterone and Oxidative stress is related to Endocrinology.

Joseph Loscalzo has included themes like Endothelial stem cell, Pharmacology and Vasodilation in his Nitric oxide study. His studies link Cell biology with Biochemistry. His research ties Thrombosis and Cardiology together.

He most often published in these fields:

  • Internal medicine (36.87%)
  • Endocrinology (20.90%)
  • Nitric oxide (20.06%)

What were the highlights of his more recent work (between 2014-2021)?

  • Disease (10.29%)
  • Internal medicine (36.87%)
  • Computational biology (5.04%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Disease, Internal medicine, Computational biology, Network medicine and Cell biology. His research integrates issues of Bioinformatics, Function, Genomics and Human interactome, Interactome in his study of Disease. His Internal medicine research is multidisciplinary, relying on both Endocrinology and Cardiology.

His Computational biology research is multidisciplinary, incorporating perspectives in Interaction network, Gene, Gene regulatory network and Drug repositioning. His Network medicine research is multidisciplinary, incorporating elements of Precision medicine and Data science. The various areas that he examines in his Cell biology study include Glycolysis, Biochemistry, Metabolism and Redox.

Between 2014 and 2021, his most popular works were:

  • Uncovering disease-disease relationships through the incomplete interactome (750 citations)
  • Genetic Misdiagnoses and the Potential for Health Disparities (341 citations)
  • Hypoxia-Mediated Increases in L-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress. (178 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

His main research concerns Disease, Computational biology, Network medicine, Genetics and Cell biology. His Disease research is multidisciplinary, incorporating elements of Precision medicine, Bioinformatics, Genomics and Human interactome, Interactome. His research on Network medicine concerns the broader Internal medicine.

His work on Dyslipidemia, Aortic valve and Pharmacological therapy is typically connected to Network analysis and Retinol binding protein 4 as part of general Internal medicine study, connecting several disciplines of science. Joseph Loscalzo interconnects Preclinical imaging, Biochemistry, Transcription and Live cell imaging in the investigation of issues within Cell biology. As part of his studies on Biochemistry, Joseph Loscalzo often connects relevant areas like Hypoxia.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Harrison's Principles of Internal Medicine

Dennis L Kasper;Tinsley Randolph Harrison;Stephen L. Hauser;J. Larry Jameson.
(1950)

12280 Citations

Network Medicine: A Network-Based Approach to Human Disease

Albert-László Barabási;Natali Gulbahce;Natali Gulbahce;Natali Gulbahce;Joseph Loscalzo.
Nature Reviews Genetics (2011)

4273 Citations

Endothelial Cells in Physiology and in the Pathophysiology of Vascular Disorders

Douglas B. Cines;Eleanor S. Pollak;Clayton A. Buck;Joseph Loscalzo.
Blood (1998)

3397 Citations

Biochemistry of nitric oxide and its redox-activated forms

Jonathan S. Stamler;David J. Singel;Joseph Loscalzo.
Science (1992)

3389 Citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

Stuart A. Lipton;Yun-Beom Choi;Yun-Beom Choi;Zhuo-Hua Pan;Zhuo-Hua Pan;Sizheng Z. Lei;Sizheng Z. Lei.
Nature (1993)

2987 Citations

Homocysteine and atherothrombosis

George N. Welch;Joseph Loscalzo.
The New England Journal of Medicine (1998)

2936 Citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds

Jonathan S. Stamler;Daniel I. Simon;John A. Osborne;Mark E. Mullins.
Proceedings of the National Academy of Sciences of the United States of America (1992)

1681 Citations

Pulmonary arterial hypertension.

Harrison W Farber;Joseph Loscalzo.
The New England Journal of Medicine (2004)

1538 Citations

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

J S Stamler;O Jaraki;J Osborne;D I Simon.
Proceedings of the National Academy of Sciences of the United States of America (1992)

1482 Citations

Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans.

Mark A. Creager;John P. Cooke;Michael E. Mendelsohn;Shelly J. Gallagher.
Journal of Clinical Investigation (1990)

1322 Citations

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