D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Engineering and Technology D-index 86 Citations 32,643 294 World Ranking 78 National Ranking 38
Medicine D-index 95 Citations 36,879 386 World Ranking 4599 National Ranking 2599

Research.com Recognitions

Awards & Achievements

2009 - Member of the National Academy of Medicine (NAM)

2006 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Artificial intelligence

His primary areas of investigation include Informatics, Genetics, Bioinformatics, Health care and Gene expression profiling. The study incorporates disciplines such as Chart, Medical record, Health informatics, World Wide Web and Data science in addition to Informatics. His study focuses on the intersection of Genetics and fields such as Computational biology with connections in the field of Genome, Functional genomics and Microarray analysis techniques.

Isaac S. Kohane interconnects Major depressive disorder, Genetic testing, Disease and DNA sequencing in the investigation of issues within Bioinformatics. He usually deals with Major depressive disorder and limits it to topics linked to Mendelian randomization and Case-control study and Genome-wide association study. His Gene expression profiling study combines topics in areas such as Regulation of gene expression and Inclusion body myositis.

His most cited work include:

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways (5484 citations)
  • Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 (1650 citations)
  • Gene regulation and DNA damage in the ageing human brain. (1437 citations)

What are the main themes of his work throughout his whole career to date?

Isaac S. Kohane mainly investigates Internal medicine, Genetics, Gene, Bioinformatics and Disease. His work carried out in the field of Internal medicine brings together such families of science as Gastroenterology and Endocrinology. His Genetics study often links to related topics such as Computational biology.

His work in Gene expression and Gene expression profiling are all subfields of Gene research. His specific area of interest is Disease, where Isaac S. Kohane studies Ulcerative colitis. His study looks at the intersection of Ulcerative colitis and topics like Crohn's disease with Surgery.

He most often published in these fields:

  • Internal medicine (24.23%)
  • Genetics (17.95%)
  • Gene (15.77%)

What were the highlights of his more recent work (between 2016-2021)?

  • Artificial intelligence (7.95%)
  • Health care (8.85%)
  • MEDLINE (9.36%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Artificial intelligence, Health care, MEDLINE, Machine learning and Computational biology. His work on Deep learning, Artificial neural network and Benchmark as part of general Artificial intelligence research is frequently linked to Set, thereby connecting diverse disciplines of science. His research in Health care focuses on subjects like Retrospective cohort study, which are connected to Observational study.

His Computational biology study typically links adjacent topics like Gene expression. His Gene expression research is classified as research in Gene. His Phenotype study deals with the bigger picture of Genetics.

Between 2016 and 2021, his most popular works were:

  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression (1131 citations)
  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression (1131 citations)
  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression (1131 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Artificial intelligence

Isaac S. Kohane mainly focuses on Artificial intelligence, Health care, MEDLINE, Genetics and Retrospective cohort study. His Artificial intelligence research includes elements of Machine learning and Natural language processing. His research integrates issues of Artificial neural network, Health informatics and Sex factors in his study of MEDLINE.

His research in Health informatics intersects with topics in World Wide Web, Workflow and Data visualization. His study in Retrospective cohort study is interdisciplinary in nature, drawing from both Test, Observational study, Pharmacy, Confidence interval and Emergency medicine. Isaac S. Kohane studied Disease and Functional studies that intersect with Bioinformatics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir.
Nature (2008)

5348 Citations

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

Mary Elizabeth Patti;Atul J. Butte;Sarah Crunkhorn;Kenneth Cusi.
Proceedings of the National Academy of Sciences of the United States of America (2003)

2159 Citations

Gene regulation and DNA damage in the ageing human brain.

Tao Lu;Ying Pan;Shyan Yuan Kao;Cheng Li.
Nature (2004)

1823 Citations

Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements.

A J Butte;I S Kohane.
pacific symposium on biocomputing (1999)

1256 Citations

A mega-analysis of genome-wide association studies for major depressive disorder

Stephan Ripke;Naomi R Wray;Cathryn M Lewis;Steven P Hamilton.
Molecular Psychiatry (2013)

1062 Citations

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

Scott L Carter;Aron C Eklund;Aron C Eklund;Isaac S Kohane;Lyndsay N Harris.
Nature Genetics (2006)

1001 Citations

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Naomi R. Wray;Stephan Ripke;Stephan Ripke;Stephan Ripke;Manuel Mattheisen;MacIej Trzaskowski.
Nature Genetics (2018)

893 Citations

Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)

Shawn N. Murphy;Shawn N. Murphy;Griffin M. Weber;Griffin M. Weber;Michael Mendis;Vivian S. Gainer.
Journal of the American Medical Informatics Association (2010)

782 Citations

Discovering statistically significant pathways in expression profiling studies

Lu Tian;Steven A. Greenberg;Sek Won Kong;Josiah Altschuler.
Proceedings of the National Academy of Sciences of the United States of America (2005)

774 Citations

Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks

Atul J. Butte;Pablo Tamayo;Donna Slonim;Todd R. Golub.
Proceedings of the National Academy of Sciences of the United States of America (2000)

740 Citations

Best Scientists Citing Isaac S. Kohane

Gerome Breen

Gerome Breen

King's College London

Publications: 126

Andrew M. McIntosh

Andrew M. McIntosh

University of Edinburgh

Publications: 122

Jordan W. Smoller

Jordan W. Smoller

Harvard University

Publications: 117

Kenneth D. Mandl

Kenneth D. Mandl

Boston Children's Hospital

Publications: 116

Joshua C. Denny

Joshua C. Denny

Vanderbilt University Medical Center

Publications: 111

Cathryn M. Lewis

Cathryn M. Lewis

King's College London

Publications: 107

Stephan Ripke

Stephan Ripke

Massachusetts General Hospital

Publications: 103

Robert C. Green

Robert C. Green

Brigham and Women's Hospital

Publications: 102

Ole Mors

Ole Mors

Aarhus University Hospital

Publications: 93

Patrick F. Sullivan

Patrick F. Sullivan

University of North Carolina at Chapel Hill

Publications: 88

Roy H. Perlis

Roy H. Perlis

Harvard University

Publications: 88

Marylyn D. Ritchie

Marylyn D. Ritchie

University of Pennsylvania

Publications: 87

Thomas Werge

Thomas Werge

University of Copenhagen

Publications: 85

Ole A. Andreassen

Ole A. Andreassen

Oslo University Hospital

Publications: 81

Anders D. Børglum

Anders D. Børglum

Lundbeck (Denmark)

Publications: 81

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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