World's Best Scientists 2026 revealed!
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Engineering and Technology
USA
2026

D-Index & Metrics

Engineering and Technology

D-Index
109
Citations
51893
World Ranking
84
National Ranking
30

Medicine

D-Index
125
Citations
79661
World Ranking
3024
National Ranking
1668

Research.com Recognitions

  • 2026 - Research.com Engineering and Technology in United States Leader Award
  • 2025 - Research.com Engineering and Technology in United States Leader Award
  • 2009 - Member of the National Academy of Medicine (NAM)
  • 2006 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Isaac S. Kohane is affiliated with Harvard University in the United States and has contributed extensively to the field of medicine, with a focus on areas such as genetics, artificial intelligence, epidemiology, infectious diseases, and molecular biology.

The scientist's recent publications include:

  • Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting, 2021, New England Journal of Medicine
  • Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study, 2021, The Lancet
  • The Clinician and Dataset Shift in Artificial Intelligence, 2021, New England Journal of Medicine
  • Minimum information about clinical artificial intelligence modeling: the MI-CLAIM checklist, 2020, Nature Medicine
  • Effectiveness of the BNT162b2 mRNA COVID-19 vaccine in pregnancy, 2021, Nature Medicine

Research topics commonly addressed by the scientist encompass:

  • Machine Learning in Healthcare
  • Artificial Intelligence in Healthcare and Education
  • Genomics and Rare Diseases
  • COVID-19 Clinical Research Studies
  • Genetic Associations and Epidemiology
  • Biomedical Text Mining and Ontologies
  • Autism Spectrum Disorder Research

Frequent coauthors collaborating with Isaac S. Kohane include:

  • Gabriel A. Brat
  • Paul Avillach
  • Amelia L.M. Tan
  • Nathan Palmer
  • Tianxi Cai

Publication venues where the scientist has appeared regularly include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Medical Informatics Association
  • New England Journal of Medicine
  • NEJM AI
  • arXiv (Cornell University)

The primary fields of study for Isaac S. Kohane are in medicine. Subfields of work comprise genetics, artificial intelligence, epidemiology, infectious diseases, and molecular biology, reflecting a multidisciplinary approach.

Awards received by the scientist include:

  • Member of the National Academy of Medicine (NAM), 2009
  • Fellow of the Indian National Academy of Engineering (INAE), 2006

Best Publications

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • Machine Learning in Medicine.

    Alvin Rajkomar;Jeffrey Dean;Isaac Kohane

  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Naomi R. Wray;Stephan Ripke;Stephan Ripke;Stephan Ripke;Manuel Mattheisen;MacIej Trzaskowski

  • Artificial Intelligence in Healthcare

    Kun-Hsing Yu;Andrew L. Beam;Isaac S. Kohane;Isaac S. Kohane

  • Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

    Mary Elizabeth Patti;Atul J. Butte;Sarah Crunkhorn;Kenneth Cusi

  • Gene regulation and DNA damage in the ageing human brain.

    Tao Lu;Ying Pan;Shyan Yuan Kao;Cheng Li

  • Big Data and Machine Learning in Health Care.

    Andrew L. Beam;Isaac S. Kohane

  • A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

    Scott L Carter;Aron C Eklund;Aron C Eklund;Isaac S Kohane;Lyndsay N Harris

  • Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements.

    A J Butte;I S Kohane

  • A mega-analysis of genome-wide association studies for major depressive disorder

    Stephan Ripke;Naomi R Wray;Cathryn M Lewis;Steven P Hamilton

  • Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)

    Shawn N. Murphy;Shawn N. Murphy;Griffin M. Weber;Griffin M. Weber;Michael Mendis;Vivian S. Gainer

  • Artificial intelligence in health care: value for whom?

    Jean-David Zeitoun;Philippe Ravaud;Philippe Ravaud

  • Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting.

    Noam Barda;Noa Dagan;Yatir Ben-Shlomo;Eldad Kepten

  • Adversarial attacks on medical machine learning

    Samuel G. Finlayson;John D. Bowers;Joichi Ito;Jonathan L. Zittrain

  • Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study.

    Noam Barda;Noa Dagan;Cyrille Cohen;Miguel A Hernán

  • Discovering statistically significant pathways in expression profiling studies

    Lu Tian;Steven A. Greenberg;Sek Won Kong;Josiah Altschuler

  • Genetic Misdiagnoses and the Potential for Health Disparities

    Arjun K. Manrai;Birgit H. Funke;Heidi L. Rehm;Morten S. Olesen

  • Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks

    Atul J. Butte;Pablo Tamayo;Donna Slonim;Todd R. Golub

  • SMART on FHIR: a standards-based, interoperable apps platform for electronic health records

    Joshua C. Mandel;Joshua C. Mandel;David A. Kreda;Kenneth D. Mandl;Isaac S. Kohane

  • Human disease classification in the postgenomic era: A complex systems approach to human pathobiology

    Joseph Loscalzo;Joseph Loscalzo;Isaac Kohane;Isaac Kohane;Albert Laszlo Barabasi

  • The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

    Omri Gottesman;Helena Kuivaniemi;Gerard Tromp;W. Andrew Faucett

  • A mega-analysis of genome-wide association studies for major depressive disorder

    S. Ripke;N. R. Wray;C. M. Lewis;S. P. Hamilton

Frequent Co-Authors

Kenneth D. Mandl
Kenneth D. Mandl Harvard Medical School
Elizabeth W. Karlson
Elizabeth W. Karlson Brigham and Women's Hospital
Ashwin N. Ananthakrishnan
Ashwin N. Ananthakrishnan Harvard University
Robert M. Plenge
Robert M. Plenge Bristol Myers Squibb
Louis M. Kunkel
Louis M. Kunkel Boston Children's Hospital
Atul J. Butte
Atul J. Butte University of California, San Francisco
Alan H. Beggs
Alan H. Beggs Harvard Medical School
Roy H. Perlis
Roy H. Perlis Harvard University
Guergana Savova
Guergana Savova Harvard University

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