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P. Mark Hogarth

P. Mark Hogarth

D-Index & Metrics

Immunology

D-Index
55
Citations
9082
World Ranking
3825
National Ranking
162

Overview

P. Mark Hogarth is affiliated with the Burnet Institute in Australia. Their research predominantly addresses infectious diseases, immunology, and related fields. The scientist's work spans multiple subfields including infectious diseases, immunology, radiology, nuclear medicine and imaging, public health, environmental and occupational health, and epidemiology.

The primary topics of Hogarth's research concentrate on SARS-CoV-2 and COVID-19, monoclonal and polyclonal antibodies, COVID-19 clinical research studies, T-cell and B-cell immunology, the complement system in diseases, malaria research and control, and immune cell function and interaction.

Notable recent publications by Hogarth include:

  • Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence (2020, Science Immunology)
  • Systems serology detects functionally distinct coronavirus antibody features in children and elderly (2021, Nature Communications)
  • Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences (2021, European Respiratory Journal)
  • Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial (2021, The Lancet Infectious Diseases)
  • Decay of Fc-dependent antibody functions after mild to moderate COVID-19 (2021, Cell Reports Medicine)

Frequent coauthors in Hogarth's research include:

  • Bruce D. Wines
  • Stephen J. Kent
  • Amy W. Chung
  • Adam K. Wheatley
  • Menno C. van Zelm

Publications by Hogarth are regularly featured in venues such as bioRxiv (Cold Spring Harbor Laboratory), Allergy, Frontiers in Immunology, Nature Communications, and Cell Reports Medicine. The highest number of publications appears in the preprint server bioRxiv.

Their research contributions cover a broad range of immunological disciplines with particular emphasis on responses to infectious agents and immune system mechanisms relevant to disease pathology and clinical outcomes.

Best Publications

  • Molecular basis of Fc receptor function.

    Mark D. Hulett;P. Mark Hogarth

  • Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond

    P. Mark Hogarth;P. Mark Hogarth;P. Mark Hogarth;Geoffrey A. Pietersz;Geoffrey A. Pietersz;Geoffrey A. Pietersz

  • The IgG Fc Contains Distinct Fc Receptor (FcR) Binding Sites: The Leukocyte Receptors FcγRI and FcγRIIa Bind to a Region in the Fc Distinct from That Recognized by Neonatal FcR and Protein A

    Bruce D. Wines;Maree S. Powell;Paul W. H. I. Parren;Nadine Barnes

  • Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence.

    Gemma E. Hartley;Emily S.J. Edwards;Pei M. Aui;Nirupama Varese

  • Fc receptors are major mediators of antibody based inflammation in autoimmunity.

    P.Mark Hogarth

  • Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa.

    K. F. Maxwell;M. S. Powell;M. D. Hulett;P. A. Barton

  • FcγRI-Deficient Mice Show Multiple Alterations to Inflammatory and Immune Responses

    Nadine Barnes;Amanda L Gavin;Peck Szee Tan;Patricia Mottram

  • Structural Basis for FcγRIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes

    Paul A. Ramsland;William Farrugia;Tessa M. Bradford;Caroline Tan Sardjono

  • Systems serology detects functionally distinct coronavirus antibody features in children and elderly.

    Kevin J. Selva;Carolien E. van de Sandt;Carolien E. van de Sandt;Melissa M. Lemke;Christina Y. Lee

  • IgA receptors in health and disease.

    Bruce D. Wines;P. Mark Hogarth

  • C5a Initiates the Inflammatory Cascade in Immune Complex Peritonitis

    Jeanne Godau;Tanja Heller;Heiko Hawlisch;Matthew Trappe

  • The tetraspanin superfamily member CD151 regulates outside-in integrin αIIbβ3 signaling and platelet function

    Lai-Man Lau;Janet L. Wee;Mark D. Wright;Gregory W. Moseley

  • Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1.

    Paul A Ramsland;Natasha Willoughby;Halina M Trist;William Farrugia

  • Dimeric FcγR Ectodomains as Probes of the Fc Receptor Function of Anti-Influenza Virus IgG.

    Bruce D. Wines;Hillary A. Vanderven;Sandra E. Esparon;Anne B. Kristensen

  • Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences.

    Sheila K. Patel;Jennifer A. Juno;Wen Shi Lee;Kathleen M. Wragg

  • IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both FcγRIIA and FcγRIIB

    Carol T. Cady;Maree S. Powell;Ronald J. Harbeck;Patricia C. Giclas

  • Identification of residues in the first domain of human Fc alpha receptor essential for interaction with IgA.

    Bruce D. Wines;Mark D. Hulett;Gary P. Jamieson;Halina M. Trist

  • The Interaction of FcαRI with IgA and Its Implications for Ligand Binding by Immunoreceptors of the Leukocyte Receptor Cluster

    B D Wines;C T Sardjono;H H Trist;C S Lay

  • Antigen delivery via two molecules on the CD8 dendritic cell subset induces humoral immunity in the absence of conventional "danger"

    Alexandra J. Corbett;Irina Caminschi;Brent S. McKenzie;Brent S. McKenzie;Jamie L. Brady

  • Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial.

    Keith J Chappell;Francesca L Mordant;Zheyi Li;Danushka K Wijesundara

  • Impaired “outside-in” integrin αIIbβ3 signaling and thrombus stability in TSSC6-deficient mice

    Matt W. Goschnick;Matt W. Goschnick;Matt W. Goschnick;Lai-Man Lau;Lai-Man Lau;Lai-Man Lau;Janet L. Wee;Janet L. Wee;Janet L. Wee;Yong S. Liu;Yong S. Liu;Yong S. Liu

Frequent Co-Authors

Stephen J. Kent
Stephen J. Kent University of Melbourne
Geoffrey A. Pietersz
Geoffrey A. Pietersz Baker IDI Heart and Diabetes Institute
Mark D. Hulett
Mark D. Hulett La Trobe University
James G. Beeson
James G. Beeson Burnet Institute
Adam K. Wheatley
Adam K. Wheatley University of Melbourne
Miles P. Davenport
Miles P. Davenport University of New South Wales
Ian F. C. McKenzie
Ian F. C. McKenzie University of Melbourne
Derek N.J. Hart
Derek N.J. Hart University of Sydney
Jonathan B. Baell
Jonathan B. Baell Monash University
Katherine Kedzierska
Katherine Kedzierska University of Melbourne

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