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Immunology

D-Index
51
Citations
13597
World Ranking
4119
National Ranking
195

Overview

Pierre Bruhns is affiliated with Université Paris Cité in France and conducts research primarily within the fields of Medicine and Immunology and Microbiology. Their work spans several subfields including Immunology, Immunology and Allergy, Infectious Diseases, Physiology, and Molecular Biology.

The scientist's research focuses on various topics such as:

  • Asthma and respiratory diseases
  • Food Allergy and Anaphylaxis Research
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • Allergic Rhinitis and Sensitization
  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction

Bruhns has contributed to multiple papers in well-known academic journals. Notable recent papers include:

  • "High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics," 2020, published in Nature Biotechnology
  • "mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants," 2021, published in Immunity
  • "Smoking changes adaptive immunity with persistent effects," 2024, published in Nature
  • "Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice," 2021, published in Nature Communications
  • "The immune factors driving DNA methylation variation in human blood," 2022, published in Nature Communications

Frequent publication venues for Bruhns include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Allergy
  • Immunity
  • The Journal of Immunology
  • Nature Biotechnology

Collaboration is a significant part of Bruhns's research activities. They have co-authored papers numerous times with:

  • Bruno Iannascoli
  • Aurélien Sokal
  • Matteo Broketa
  • Darragh Duffy
  • Laurent L. Reber

Best Publications

  • Specificity and affinity of human Fcγ receptors and their polymorphic variants for human IgG subclasses

    Pierre Bruhns;Pierre Bruhns;Bruno Iannascoli;Bruno Iannascoli;Patrick England;Patrick England;David A. Mancardi;David A. Mancardi

  • Properties of mouse and human IgG receptors and their contribution to disease models

    Pierre Bruhns

  • FcγRIV : A novel FcR with distinct IgG subclass specificity

    Falk Nimmerjahn;Pierre Bruhns;Ken Horiuchi;Jeffrey V. Ravetch

  • The function of Fcγ receptors in dendritic cells and macrophages

    Martin Guilliams;Pierre Bruhns;Yvan Saeys;Hamida Hammad

  • Mouse and human FcR effector functions.

    Pierre Bruhns;Pierre Bruhns;Friederike Jönsson;Friederike Jönsson

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Colony-Stimulating Factor-1-Dependent Macrophages Are Responsible for IVIG Protection in Antibody-Induced Autoimmune Disease

    Pierre Bruhns;Astrid Samuelsson;Jeffrey W Pollard;Jeffrey V Ravetch

  • Mouse and human neutrophils induce anaphylaxis.

    Friederike Jönsson;David A. Mancardi;Yoshihiro Kita;Hajime Karasuyama

  • Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.

    Etienne Patin;Milena Hasan;Jacob Bergstedt;Vincent Rouilly

  • The RasGAP-Binding Protein p62dok Is a Mediator of Inhibitory FcγRIIB Signals in B Cells

    Idan Tamir;John C Stolpa;Cheryl D Helgason;Kazuhiro Nakamura

  • Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells

    Matthias Lochner;Caspar Ohnmacht;Caspar Ohnmacht;Laura Presley;Laura Presley;Pierre Bruhns;Pierre Bruhns

  • High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics

    Annabelle Gérard;Adam Woolfe;Guillaume Mottet;Marcel Reichen

  • Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring.

    Klaus Eyer;Raphaël C L Doineau;Carlos E Castrillon;Carlos E Castrillon;Luis Briseño-Roa

  • Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia

    Mattias Olsson;Pierre Bruhns;Pierre Bruhns;Pierre Bruhns;William A. Frazier;William A. Frazier;William A. Frazier;Jeffrey V. Ravetch;Jeffrey V. Ravetch;Jeffrey V. Ravetch

  • Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

    Petar Scepanovic;Petar Scepanovic;Cécile Alanio;Christian Hammer;Christian Hammer;Christian Hammer;Flavia Hodel;Flavia Hodel

  • The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy.

    David A. Mancardi;David A. Mancardi;Marcello Albanesi;Friederike Jönsson;Friederike Jönsson;Bruno Iannascoli;Bruno Iannascoli

  • Neutrophils mediate antibody-induced antitumor effects in mice.

    Marcello Albanesi;Marcello Albanesi;Marcello Albanesi;David A. Mancardi;David A. Mancardi;Friederike Jönsson;Friederike Jönsson;Bruno Iannascoli;Bruno Iannascoli

  • FcγRIV is a mouse IgE receptor that resembles macrophage FcεRI in humans and promotes IgE-induced lung inflammation

    David A. Mancardi;Bruno Iannascoli;Sylviane Hoos;Patrick England

  • Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies

    Caitlin Gillis;Caitlin Gillis;Aurélie Gouel-Chéron;Aurélie Gouel-Chéron;Friederike Jönsson;Friederike Jönsson;Pierre Bruhns;Pierre Bruhns

  • An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

    Friederike Jönsson;Luc de Chaisemartin;Vanessa Granger;Aurélie Gouel-Chéron

  • Human FcγRIIA induces anaphylactic and allergic reactions.

    Friederike Jönsson;Friederike Jönsson;David A. Mancardi;David A. Mancardi;Wei Zhao;Yoshihiro Kita

Frequent Co-Authors

Marc Daëron
Marc Daëron Institut Pasteur
Sylvie Chollet-Martin
Sylvie Chollet-Martin University of Paris-Saclay
Patrick England
Patrick England Institut Pasteur
Andrew J. Murphy
Andrew J. Murphy St. Jude Children's Research Hospital
Wolf H. Fridman
Wolf H. Fridman Université Paris Cité
Nico van Rooijen
Nico van Rooijen Vrije Universiteit Amsterdam
George Georgiou
George Georgiou The University of Texas at Austin
Georges Bismuth
Georges Bismuth Université Paris Cité
Andrew D. Griffiths
Andrew D. Griffiths PSL University
Marie Malissen
Marie Malissen Aix-Marseille University

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