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Andrew D. Griffiths

Andrew D. Griffiths

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
47756
World Ranking
3418
National Ranking
81

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Andrew D. Griffiths is affiliated with PSL University in France and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans several specialized subfields including Molecular Biology, Biomedical Engineering, Immunology, Epidemiology, and Radiology, Nuclear Medicine and Imaging. Griffiths's research focuses on advanced techniques in microfluidics, biosensing, immune response, and antibody research.

The main topics covered in Griffiths's publications include:

  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Monoclonal and Polyclonal Antibodies Research
  • Advanced Biosensing Techniques and Applications
  • Immune Response and Inflammation
  • Single-cell and spatial transcriptomics
  • Advanced biosensing and bioanalysis techniques
  • Sepsis Diagnosis and Treatment

Griffiths has contributed to a range of peer-reviewed papers, including recent works such as:

  • "High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics," published in 2020 in Nature Biotechnology
  • "Droplet-based microfluidics," published in 2023 in Nature Reviews Methods Primers
  • "Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap," published in 2020 in Nature Protocols
  • "Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device," published in 2022 in Science
  • "Immune Profiling Demonstrates a Common Immune Signature of Delayed Acquired Immunodeficiency in Patients With Various Etiologies of Severe Injury," published in 2021 in Critical Care Medicine

The scientist frequently collaborates with several co-authors, including:

  • Jean Baudry
  • Klaus Eyer
  • Fabienne Venet
  • Guillaume Monneret
  • Julien Textoris

Griffiths's work has been published in multiple scientific venues with repeat contributions in journals such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Nature Biotechnology
  • Nature Protocols
  • Frontiers in Immunology

Best Publications

  • Phage antibodies: filamentous phage displaying antibody variable domains

    John McCafferty;Andrew D. Griffiths;Greg Winter;David J. Chiswell

  • Methods for producing members of specific binding pairs

    John Mccafferty;Anthony Richard Pope;Kevin Stuart Johnson;Hendricus Renerus Jacobus Mattheus Hoogenboom

  • By-passing immunization: Human antibodies from V-gene libraries displayed on phage

    James D. Marks;Hennie R. Hoogenboom;Timothy P. Bonnert;John McCafferty

  • Making Antibodies by Phage Display Technology

    Greg Winter;Andrew D. Griffiths;Robert E. Hawkins;Hennie R. Hoogenboom

  • Making antibody fragments using phage display libraries

    Tim Clackson;Hennie R. Hoogenboom;Andrew D. Griffiths;Greg Winter

  • Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

    E. Sally Ward;Detlef Güssow;Andrew D. Griffiths;Peter T. Jones

  • Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains

    Hennie R. Hoogenboom;Andrew D. Griffiths;Kevin S. Johnson;David J. Chiswell

  • Single-cell analysis and sorting using droplet-based microfluidics

    Linas Mazutis;John Gilbert;W Lloyd Ung;David A Weitz

  • Man-made cell-like compartments for molecular evolution

    Dan S. Tawfik;Andrew D. Griffiths

  • Isolation of high affinity human antibodies directly from large synthetic repertoires.

    A D Griffiths;S C Williams;O Hartley;I M Tomlinson

  • Human anti‐self antibodies with high specificity from phage display libraries.

    A D Griffiths;M Malmqvist;J D Marks;J M Bye

  • Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

    Jeremy J. Agresti;Eugene Antipov;Adam R. Abate;Keunho Ahn

  • Multivalent and multispecific binding proteins, their manufacture and use

    Kaspar-Philipp Holliger;Andrew David Griffiths;Hendricus Renerus Jacobus Matheus Hoogenboom;Magnus Malmqvist

  • By-passing immunization: building high affinity human antibodies by chain shuffling.

    James D. Marks;Andrew D. Griffiths;Magnus Malmqvist;Tim P. Clackson

  • Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

    Jean-Christophe Baret;Oliver J. Miller;Valerie Taly;Michaël Ryckelynck

  • Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

    Jenifer Clausell-Tormos;Diana Lieber;Jean-Christophe Baret;Abdeslam El-Harrak

  • Drop-based microfluidic devices for encapsulation of single cells

    Sarah Köster;Francesco E. Angilè;Honey Duan;Jeremy J. Agresti

  • Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

    Deniz Pekin;Yousr Skhiri;Jean-Christophe Baret;Jean-Christophe Baret;Delphine Le Corre

  • Amplification of complex gene libraries by emulsion PCR

    Richard Williams;Sergio G Peisajovich;Oliver J Miller;Shlomo Magdassi

  • Miniaturising the laboratory in emulsion droplets

    Andrew D. Griffiths;Dan S. Tawfik

Frequent Co-Authors

Dan S. Tawfik
Dan S. Tawfik Weizmann Institute of Science
James D. Marks
James D. Marks University of California, San Francisco
Greg Winter
Greg Winter University of Cambridge
Jérôme Bibette
Jérôme Bibette PSL University
David A. Weitz
David A. Weitz Harvard University
Hennie R. Hoogenboom
Hennie R. Hoogenboom Maastricht University
Pierre Bruhns
Pierre Bruhns Université Paris Cité
Fabienne Venet
Fabienne Venet Claude Bernard University Lyon 1
Donald Hilvert
Donald Hilvert ETH Zurich
Shlomo Magdassi
Shlomo Magdassi Hebrew University of Jerusalem

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