What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Stereochemistry, Catalysis, Biochemistry, Protein engineering and Directed evolution.
Donald Hilvert has researched Stereochemistry in several fields, including Diels–Alder reaction, Hydrolase, Chorismate mutase, Active site and Substrate.
His Catalysis research is multidisciplinary, relying on both Combinatorial chemistry, Hapten and Rational design.
His research on Biochemistry frequently links to adjacent areas such as Biophysics.
His research integrates issues of Protein structure, Enzyme catalysis and Protein folding in his study of Protein engineering.
His studies in Directed evolution integrate themes in fields like Mutagenesis, Protein design and Nanotechnology.
His most cited work include:
- De novo computational design of retro-aldol enzymes. (889 citations)
- Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction (599 citations)
- Protein Design by Directed Evolution (308 citations)
What are the main themes of his work throughout his whole career to date?
Donald Hilvert mainly focuses on Stereochemistry, Biochemistry, Catalysis, Chorismate mutase and Enzyme.
Donald Hilvert studied Stereochemistry and Active site that intersect with Enzyme catalysis and Binding site.
His Biochemistry research includes elements of Biophysics and Antibody.
His Catalysis research incorporates themes from Combinatorial chemistry, Carboxylate and Hapten.
His Chorismate mutase research integrates issues from Isomerase, Crystallography, Computational biology and Protein structure.
His research links Protein design with Protein engineering.
He most often published in these fields:
- Stereochemistry (38.54%)
- Biochemistry (27.07%)
- Catalysis (25.16%)
What were the highlights of his more recent work (between 2017-2021)?
- Directed evolution (15.61%)
- Stereochemistry (38.54%)
- Lumazine synthase (6.37%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Directed evolution, Stereochemistry, Lumazine synthase, Biophysics and Catalysis.
His work deals with themes such as Combinatorial chemistry, Protein engineering, Non canonical and Biocatalysis, which intersect with Directed evolution.
The concepts of his Stereochemistry study are interwoven with issues in Myoglobin, Mutant, Enzyme kinetics, Heme and Transition state analog.
His research in Lumazine synthase intersects with topics in Aquifex aeolicus, Self-assembly, Nanoreactor, Cell specific and Antibody.
His is involved in several facets of Catalysis study, as is seen by his studies on Active site and Enzyme catalysis.
His Active site research is multidisciplinary, incorporating elements of Side chain and Ethyl diazoacetate.
Between 2017 and 2021, his most popular works were:
- Directed Evolution of Protein Catalysts. (139 citations)
- Speeding up enzyme discovery and engineering with ultrahigh-throughput methods. (47 citations)
- Evolution of a highly active and enantiospecific metalloenzyme from short peptides. (45 citations)
In his most recent research, the most cited papers focused on:
Donald Hilvert spends much of his time researching Directed evolution, Protein engineering, Nanotechnology, Throughput and Biochemical engineering.
The various areas that Donald Hilvert examines in his Directed evolution study include Oxidase test, Substrate and Cyclohexylamine oxidase.
His work carried out in the field of Protein engineering brings together such families of science as Rational engineering, RNA metabolism and Oligonucleotide.
His work in the fields of Nanobiotechnology overlaps with other areas such as Artificial Organelles.
The study incorporates disciplines such as Lumazine synthase and Enzyme in addition to Catalysis.
In his study, which falls under the umbrella issue of Function, Stereochemistry is strongly linked to Directed Molecular Evolution.
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