World's Best Scientists 2026 revealed!
Donald Hilvert

Donald Hilvert

D-Index & Metrics

Chemistry

D-Index
93
Citations
25566
World Ranking
1827
National Ranking
39

Donald Hilvert publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Donald Hilvert sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 405 publications — 81st percentile

81% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Donald Hilvert D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Donald Hilvert sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 93 D-Index — 90th percentile

90% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 2016 - Fellow of the American Academy of Arts and Sciences
  • 1993 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1991 - Fellow of Alfred P. Sloan Foundation

Overview

Donald Hilvert is affiliated with ETH Zurich in Switzerland and has conducted research primarily within the fields of Biochemistry, Genetics, and Molecular Biology. Their work spans multiple subfields, including Molecular Biology, Materials Chemistry, Radiology, Nuclear Medicine and Imaging, Ecology, and Pharmacology.

The research topics addressed by Hilvert include:

  • Enzyme Catalysis and Immobilization
  • Protein Structure and Dynamics
  • Chemical Synthesis and Analysis
  • Enzyme Structure and Function
  • Microbial Metabolic Engineering and Bioproduction
  • Bacteriophages and microbial interactions
  • Microbial Natural Products and Biosynthesis

Hilvert has published extensively, with recent notable papers including:

  • "An evolution-based model for designing chorismate mutase enzymes," 2020, Science
  • "The road to fully programmable protein catalysis," 2022, Nature
  • "How directed evolution reshapes the energy landscape in an enzyme to boost catalysis," 2020, Science
  • "Protein Cages: From Fundamentals to Advanced Applications," 2022, Chemical Reviews
  • "Evolution of dynamical networks enhances catalysis in a designer enzyme," 2021, Nature Chemistry

Common publication venues for Hilvert's work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faraday Discussions
  • Nature Communications
  • ACS Catalysis
  • Journal of the American Chemical Society

Hilvert frequently collaborates with other researchers, including:

  • H. Adrian Bunzel
  • Mikail D. Levasseur
  • Thomas G. W. Edwardson
  • T.M. Schmeing
  • Marcel Grogg

The scientist has received several fellowships, including:

  • Fellow of the American Academy of Arts and Sciences (2016)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1993)
  • Fellow of Alfred P. Sloan Foundation (1991)

Best Publications

  • De novo computational design of retro-aldol enzymes.

    Lin Jiang;Eric A. Althoff;Fernando R. Clemente;Lindsey Doyle

  • Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction

    Justin B. Siegel;Alexandre Zanghellini;Helena M. Lovick;Gert Kiss

  • Directed Evolution of Protein Catalysts.

    Cathleen Zeymer;Donald Hilvert

  • Protein Design by Directed Evolution

    Christian Jäckel;Peter Kast;Donald Hilvert

  • Directed Evolution of a Protein Container

    Bigna Wörsdörfer;Kenneth J. Woycechowsky;Donald Hilvert

  • The road to fully programmable protein catalysis

    Unknown

  • Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase

    Richard Obexer;Alexei Godina;Alexei Godina;Xavier Garrabou;Peer R. E. Mittl

  • Iterative approach to computational enzyme design

    Heidi K. Privett;Gert Kiss;Toni M. Lee;Rebecca Blomberg

  • Precision is essential for efficient catalysis in an evolved Kemp eliminase

    Rebecca Blomberg;Hajo Kries;Daniel M. Pinkas;Peer R. E. Mittl

  • Critical Analysis of Antibody Catalysis

    Donald Hilvert

  • Evolution of a designed retro-aldolase leads to complete active site remodeling

    Lars Giger;Sami Caner;Richard Obexer;Peter Kast

  • An evolution-based model for designing chorismate mutase enzymes.

    William P. Russ;Matteo Figliuzzi;Christian Stocker;Pierre Barrat-Charlaix;Pierre Barrat-Charlaix

  • Antibody catalysis of the Diels-Alder reaction

    Donald Hilvert;Kenneth W. Hill;Karen D. Nared;Maria Teresa M. Auditor

  • Minimalist active-site redesign: teaching old enzymes new tricks.

    Miguel D. Toscano;Kenneth J. Woycechowsky;Donald Hilvert

  • Selenosubtilisin as a glutathione peroxidase mimic

    Zhen Ping Wu;Donald Hilvert

  • De novo enzymes by computational design.

    Hajo Kries;Rebecca Blomberg;Donald Hilvert

  • Investigating and Engineering Enzymes by Genetic Selection.

    Sean V. Taylor;Peter Kast;Donald Hilvert

  • Conversion of a protease into an acyl transferase: selenolsubtilisin

    Zhen Ping Wu;Donald Hilvert

  • Design of Protein Catalysts

    Donald Hilvert

  • Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart

    Matthew R. Haynes;Enrico A. Stura;Donald Hilvert;Ian A. Wilson

  • Large rate accelerations in antibody catalysis by strategic use of haptenic charge

    Simon N. Thorn;Richard G. Daniels;Maria-Teresa M. Auditor;Donald Hilvert

Frequent Co-Authors

David Baker
David Baker University of Washington
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Kendall N. Houk
Kendall N. Houk University of California, Los Angeles
Kazuya Kikuchi
Kazuya Kikuchi Osaka University
Barry L. Stoddard
Barry L. Stoddard Fred Hutchinson Cancer Research Center
Andrew D. Griffiths
Andrew D. Griffiths PSL University
William J. Rutter
William J. Rutter University of California, San Francisco
Nenad Ban
Nenad Ban ETH Zurich

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