D-Index & Metrics Best Publications
Biology and Biochemistry
Israel
2022

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 89 Citations 29,564 207 World Ranking 1173 National Ranking 9

Research.com Recognitions

Awards & Achievements

2022 - Research.com Biology and Biochemistry in Israel Leader Award

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

Dan S. Tawfik mostly deals with Genetics, Biochemistry, Directed evolution, Gene and Enzyme. Dan S. Tawfik interconnects Protein structure and Computational biology in the investigation of issues within Genetics. PON1, Enzyme kinetics and Protein engineering are the subjects of his Biochemistry studies.

His work carried out in the field of Directed evolution brings together such families of science as Chaperonin, Saccharomyces cerevisiae and Active site. His Enzyme research is multidisciplinary, incorporating elements of Lactonase, Lactonase activity and Promiscuity. His study looks at the relationship between Function and fields such as Evolvability, as well as how they intersect with chemical problems.

His most cited work include:

  • Man-made cell-like compartments for molecular evolution (938 citations)
  • Kemp elimination catalysts by computational enzyme design (933 citations)
  • Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective (853 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Biochemistry, Enzyme, Genetics, Directed evolution and Gene. His Enzyme research includes elements of Stereochemistry, Recombinant DNA and Catalysis. His studies deal with areas such as Enzyme catalysis, Hydrolysis, Hapten and Binding site as well as Stereochemistry.

His Catalysis research includes themes of Combinatorial chemistry, Antibody, Abzyme and Substrate. His study in Genetics is interdisciplinary in nature, drawing from both Protein structure and Computational biology. His work deals with themes such as Protein engineering and Enzyme kinetics, which intersect with Directed evolution.

He most often published in these fields:

  • Biochemistry (34.21%)
  • Enzyme (25.66%)
  • Genetics (23.03%)

What were the highlights of his more recent work (between 2017-2021)?

  • Enzyme (25.66%)
  • Biochemistry (34.21%)
  • Stereochemistry (16.45%)

In recent papers he was focusing on the following fields of study:

Dan S. Tawfik spends much of his time researching Enzyme, Biochemistry, Stereochemistry, Gene and Function. His work on Cyclosarin, Active site and Hydrolase as part of his general Enzyme study is frequently connected to Tubulin, thereby bridging the divide between different branches of science. His Nucleic acid, Nerve agent and Phosphodiester bond study in the realm of Biochemistry connects with subjects such as Dimethylsulfoniopropionate and Context.

His studies in Stereochemistry integrate themes in fields like Amino acid, Norvaline, Valine and Crystal structure. His Gene study deals with the bigger picture of Genetics. His work on Allele, Mutant and Pleiotropy as part of general Genetics study is frequently linked to Glutamate dehydrogenase, therefore connecting diverse disciplines of science.

Between 2017 and 2021, his most popular works were:

  • Evolution of chalcone isomerase from a noncatalytic ancestor. (57 citations)
  • Automated Design of Efficient and Functionally Diverse Enzyme Repertoires (51 citations)
  • Design and in vitro realization of carbon-conserving photorespiration (48 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

His main research concerns Enzyme, Biochemistry, Amino acid, Directed evolution and Epistasis. His Enzyme study combines topics from a wide range of disciplines, such as Computational biology and Nucleotide. In most of his Biochemistry studies, his work intersects topics such as Function.

Dan S. Tawfik has included themes like Stereochemistry and Protein biosynthesis in his Amino acid study. The study incorporates disciplines such as Evolutionism, Molecular evolution and Biochemical engineering in addition to Directed evolution. His Epistasis study is associated with Genetics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

Olga Khersonsky;Dan S Tawfik.
Annual Review of Biochemistry (2010)

1341 Citations

Man-made cell-like compartments for molecular evolution

Dan S. Tawfik;Andrew D. Griffiths.
Nature Biotechnology (1998)

1319 Citations

Kemp elimination catalysts by computational enzyme design

Daniela Röthlisberger;Olga Khersonsky;Andrew M. Wollacott;Lin Jiang.
Nature (2008)

1281 Citations

The 'evolvability' of promiscuous protein functions.

Amir Aharoni;Leonid Gaidukov;Olga Khersonsky;Stephen McQ Gould.
Nature Genetics (2005)

864 Citations

Protein dynamism and evolvability.

Nobuhiko Tokuriki;Dan S. Tawfik.
Science (2009)

772 Citations

Antibody Multispecificity Mediated by Conformational Diversity

Leo C. James;Pietro Roversi;Dan S. Tawfik.
Science (2003)

753 Citations

Structure and Evolution of the Serum Paraoxonase Family of Detoxifying and Anti-Atherosclerotic Enzymes

Michal Harel;Amir Aharoni;Leonid Gaidukov;Boris Brumshtein.
Nature Structural & Molecular Biology (2004)

733 Citations

The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

Arren Bar-Even;Elad Noor;Yonatan Savir;Wolfram Liebermeister.
Biochemistry (2011)

705 Citations

Stability effects of mutations and protein evolvability

Nobuhiko Tokuriki;Dan S Tawfik.
Current Opinion in Structural Biology (2009)

688 Citations

Enzyme promiscuity: evolutionary and mechanistic aspects.

Olga Khersonsky;Cintia Roodveldt;Dan S Tawfik.
Current Opinion in Chemical Biology (2006)

672 Citations

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