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Biology and Biochemistry
Israel
2025

D-Index & Metrics

Biology and Biochemistry

D-Index
106
Citations
39864
World Ranking
1151
National Ranking
8

Research.com Recognitions

  • 2025 - Research.com Biology and Biochemistry in Israel Leader Award
  • 2023 - Research.com Biology and Biochemistry in Israel Leader Award
  • 2022 - Research.com Biology and Biochemistry in Israel Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Dan S. Tawfik is affiliated with the Weizmann Institute of Science in Israel. Their research primarily focuses on biochemistry, genetics, and molecular biology, with an emphasis on molecular biology as a major subfield.

Their scientific work spans several specialized areas, including:

  • RNA and protein synthesis mechanisms
  • Enzyme structure and function
  • Protein structure and dynamics
  • Genomics and phylogenetic studies
  • Bacterial genetics and biotechnology
  • RNA modifications and cancer
  • Photosynthetic processes and mechanisms

Tawfik has contributed extensively to the scientific literature, with a presence in prominent publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory) with 13 publications
  • Proceedings of the National Academy of Sciences with 5 publications
  • Journal of the American Chemical Society with 3 publications
  • Protein Science with 3 publications
  • eLife with 2 publications

Notable recent papers authored or coauthored by Tawfik include:

  • On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life, 2021, Proceedings of the National Academy of Sciences
  • The evolution of oxygen-utilizing enzymes suggests early biosphere oxygenation, 2021, Nature Ecology & Evolution
  • Primordial emergence of a nucleic acid-binding protein via phase separation and statistical ornithine-to-arginine conversion, 2020, Proceedings of the National Academy of Sciences
  • On the emergence of P-Loop NTPase and Rossmann enzymes from a Beta-Alpha-Beta ancestral fragment, 2020, eLife
  • Bridging Themes: Short Protein Segments Found in Different Architectures, 2021, Molecular Biology and Evolution

The scientist has collaborated frequently with several researchers, including:

  • Liam M. Longo
  • Dragana Despotović
  • Jagoda Jabłońska
  • Michal Sharon
  • Saurav Mallik

Dan S. Tawfik is recognized as a member of the European Molecular Biology Organization (EMBO), which signifies a formal professional affiliation in the scientific community.

Best Publications

  • Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

    Olga Khersonsky;Dan S Tawfik

  • Kemp elimination catalysts by computational enzyme design

    Daniela Röthlisberger;Olga Khersonsky;Andrew M. Wollacott;Lin Jiang

  • Man-made cell-like compartments for molecular evolution

    Dan S. Tawfik;Andrew D. Griffiths

  • The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

    Arren Bar-Even;Elad Noor;Yonatan Savir;Wolfram Liebermeister

  • The 'evolvability' of promiscuous protein functions.

    Amir Aharoni;Leonid Gaidukov;Olga Khersonsky;Stephen McQ Gould

  • Protein dynamism and evolvability.

    Nobuhiko Tokuriki;Dan S. Tawfik

  • Stability effects of mutations and protein evolvability

    Nobuhiko Tokuriki;Dan S Tawfik

  • Structure and Evolution of the Serum Paraoxonase Family of Detoxifying and Anti-Atherosclerotic Enzymes

    Michal Harel;Amir Aharoni;Leonid Gaidukov;Boris Brumshtein

  • Antibody Multispecificity Mediated by Conformational Diversity

    Leo C. James;Pietro Roversi;Dan S. Tawfik

  • Enzyme promiscuity: evolutionary and mechanistic aspects.

    Olga Khersonsky;Cintia Roodveldt;Dan S Tawfik

  • Conformational diversity and protein evolution--a 60-year-old hypothesis revisited.

    Leo C. James;Dan S. Tawfik

  • How Protein Stability and New Functions Trade Off

    Nobuhiko Tokuriki;Francois Stricher;Luis Serrano;Dan S. Tawfik

  • Local fitness landscape of the green fluorescent protein.

    Karen S. Sarkisyan;Dmitry A. Bolotin;Margarita V. Meer;Dinara R. Usmanova;Dinara R. Usmanova

  • Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.

    Adi Goldenzweig;Moshe Goldsmith;Shannon E. Hill;Or Gertman

  • Amplification of complex gene libraries by emulsion PCR

    Richard Williams;Sergio G Peisajovich;Oliver J Miller;Shlomo Magdassi

  • Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase.

    Olga Khersonsky;Dan S. Tawfik

  • Miniaturising the laboratory in emulsion droplets

    Andrew D. Griffiths;Dan S. Tawfik

  • Mutational effects and the evolution of new protein functions

    Misha Soskine;Dan S. Tawfik

  • ΜΕΘΟΔΟΣ ΔΙΑΧΩΡΙΣΜΟΥ IN VITRO

    Griffiths Andrew;Tawfik Dan

  • Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein

    Shimon Bershtein;Michal Segal;Roy Bekerman;Nobuhiko Tokuriki

Frequent Co-Authors

Andrew D. Griffiths
Andrew D. Griffiths PSL University
Joel L. Sussman
Joel L. Sussman Weizmann Institute of Science
Zelig Eshhar
Zelig Eshhar Weizmann Institute of Science
David Baker
David Baker University of Washington
Israel Silman
Israel Silman Weizmann Institute of Science
Shlomo Magdassi
Shlomo Magdassi Hebrew University of Jerusalem
Nir Ben-Tal
Nir Ben-Tal Tel Aviv University
Arren Bar-Even
Arren Bar-Even Max Planck Society
Florian Hollfelder
Florian Hollfelder University of Cambridge
Leo C. James
Leo C. James MRC Laboratory of Molecular Biology

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