World's Best Scientists 2026 revealed!
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Israel Silman

D-Index & Metrics

Chemistry

D-Index
89
Citations
37146
World Ranking
2132
National Ranking
16

Biology and Biochemistry

D-Index
92
Citations
38640
World Ranking
2178
National Ranking
22

Israel Silman publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Israel Silman sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 644 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 253 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 431 publications — 83rd percentile

83% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Israel Silman D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Israel Silman sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 776 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 647 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 89 D-Index — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Israel Silman is affiliated with the Weizmann Institute of Science in Israel and has a research focus primarily in the fields of Biochemistry, Genetics and Molecular Biology, with additional work in Medicine. Their scientific contributions cover a range of topics related to molecular biology and pharmacology.

The main topics of their research include:

  • Cholinesterase and Neurodegenerative Diseases
  • Computational Drug Discovery Methods
  • Machine Learning in Bioinformatics
  • Medicinal Plants and Neuroprotection
  • Enzyme function and inhibition
  • Protein Structure and Dynamics
  • RNA and protein synthesis mechanisms

Israel Silman has published extensively across various subfields such as Molecular Biology, Pharmacology, Computational Theory and Mathematics, Complementary and Alternative Medicine, and Cell Biology.

Frequent co-authors of Israel Silman include:

  • Joel L. Sussman
  • Yacov Ashani
  • Jacques-Philippe Colletier
  • Tamar Unger
  • Shira Albeck

The scientist's work has appeared in several reputable publication venues, including:

  • Proteins Structure Function and Bioinformatics
  • Protein Science
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Medicinal Chemistry
  • Progress in Biophysics and Molecular Biology

Some recent papers authored by or involving Israel Silman are:

  • "The multiple biological roles of the cholinesterases" (2020), published in Progress in Biophysics and Molecular Biology
  • "Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice" (2020), published in Journal of Medicinal Chemistry
  • "A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides" (2020), published in Molecules
  • "Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification" (2023), published in FEBS Journal
  • "Do "Newly Born" orphan proteins resemble "Never Born" proteins? A study using three deep learning algorithms" (2023), published in Proteins Structure Function and Bioinformatics

Best Publications

  • Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein

    Joel L. Sussman;Michal Harel;Felix Frolow;Christian Oefner

  • The α/β hydrolase fold

    David L. Ollis;Eong Cheah;Miroslaw Cygler;Bauke Dijkstra

  • Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.

    M Harel;I Schalk;L Ehret-Sabatier;F Bouet

  • FoldIndex©: a simple tool to predict whether a given protein sequence is intrinsically unfolded

    Jaime Prilusky;Clifford E. Felder;Tzviya Zeev-Ben-Mordehai;Edwin H. Rydberg

  • Function and structure of inherently disordered proteins

    A Keith Dunker;Israel Silman;Vladimir N Uversky;Vladimir N Uversky;Joel L Sussman

  • Acetylcholinesterase: From 3D structure to function

    Hay Dvir;Israel Silman;Michal Harel;Terrone L. Rosenberry

  • Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs.

    Gitay Kryger;Israel Silman;Joel L Sussman

  • Structure and Evolution of the Serum Paraoxonase Family of Detoxifying and Anti-Atherosclerotic Enzymes

    Michal Harel;Amir Aharoni;Leonid Gaidukov;Boris Brumshtein

  • Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins

    Miroslaw Cygler;Joseph D. Schrag;Joel L. Sussman;Michal Harel

  • Acetylcholinesterase: ‘classical’ and ‘non-classical’ functions and pharmacology

    Israel Silman;Joel L Sussman

  • Specific chemical and structural damage to proteins produced by synchrotron radiation.

    Martin Weik;Raimond B. G. Ravelli;Gitay Kryger;Sean McSweeney

  • Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.

    Adi Goldenzweig;Moshe Goldsmith;Shannon E. Hill;Or Gertman

  • Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A.

    Mia L. Raves;Michal Harel;Yuan Ping Pang;Israel Silman

  • A structural motif of acetylcholinesterase that promotes amyloid β-peptide fibril formation

    G. V. De Ferrari;M. A. Canales;I. Shin;L. M. Weiner

  • Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

    Yoseph Shaaltiel;Daniel Bartfeld;Sharon Hashmueli;Gideon Baum

  • The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase.

    Michal Harel;Daniel M. Quinn;Haridasan K. Nair;Israel Silman

  • Water-insoluble derivatives of enzymes, antigens, and antibodies.

    Unknown

  • Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II

    Gitay Kryger;Michal Harel;Kurt Giles;Lilly Toker

  • Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis.

    M Harel;J L Sussman;E Krejci;S Bon

  • Three‐dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors

    Michal Harel;Gitay Kryger;Terrone L. Rosenberry;William D. Mallender

  • Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution.

    H.M Greenblatt;G Kryger;T.T Lewis;I Silman

Frequent Co-Authors

Joel L. Sussman
Joel L. Sussman Weizmann Institute of Science
Michal Harel
Michal Harel Weizmann Institute of Science
Anthony H. Futerman
Anthony H. Futerman Weizmann Institute of Science
Lev Weiner
Lev Weiner Weizmann Institute of Science
Hualiang Jiang
Hualiang Jiang Chinese Academy of Sciences
Florian Nachon
Florian Nachon Centre national de la recherche scientifique, CNRS
Yadin Dudai
Yadin Dudai Weizmann Institute of Science
Dan S. Tawfik
Dan S. Tawfik Weizmann Institute of Science
Raimond B. G. Ravelli
Raimond B. G. Ravelli Maastricht University
Jean Massoulié
Jean Massoulié École Normale Supérieure

External Links

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Publications: 66

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Weizmann Institute of Science

Publications: 60

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Centre national de la recherche scientifique, CNRS

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