What is she best known for?
The fields of study she is best known for:
Butyrylcholinesterase, Biochemistry, Acetylcholinesterase, Enzyme and Stereochemistry are her primary areas of study.
Her Butyrylcholinesterase study combines topics from a wide range of disciplines, such as Cholinesterase, Paraoxon, Mutant, Butyrylthiocholine and Active site.
Her studies in Active site integrate themes in fields like Benzoylcholine, Substrate and Chromatography.
Her Acetylcholinesterase research integrates issues from Endocrinology, Cholinergic and Carboxylesterase.
Her Enzyme study combines topics in areas such as Rate equation, Reaction rate, Catalysis, Photochemistry and Oxygen.
Her research in Stereochemistry intersects with topics in Acid anhydride hydrolase, Protein disulfide-isomerase, Chinese hamster ovary cell, Recombinant DNA and Gel electrophoresis.
Her most cited work include:
- Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products. (554 citations)
- Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine (476 citations)
- Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma (402 citations)
What are the main themes of her work throughout her whole career to date?
Her main research concerns Butyrylcholinesterase, Biochemistry, Acetylcholinesterase, Stereochemistry and Cholinesterase.
Her Butyrylcholinesterase research incorporates elements of Mutant, Molecular biology, Chromatography, Pharmacology and Nerve agent.
Her Biochemistry study focuses mostly on Enzyme, Serine, Tyrosine, Amino acid and Butyrylthiocholine.
The concepts of her Enzyme study are interwoven with issues in Mutagenesis and Point mutation.
Oksana Lockridge works mostly in the field of Acetylcholinesterase, limiting it down to topics relating to Organophosphate and, in certain cases, Paraoxon, as a part of the same area of interest.
Her study explores the link between Stereochemistry and topics such as Active site that cross with problems in Binding site.
She most often published in these fields:
- Butyrylcholinesterase (65.55%)
- Biochemistry (44.12%)
- Acetylcholinesterase (33.19%)
What were the highlights of her more recent work (between 2011-2020)?
- Butyrylcholinesterase (65.55%)
- Biochemistry (44.12%)
- Acetylcholinesterase (33.19%)
In recent papers she was focusing on the following fields of study:
Oksana Lockridge mostly deals with Butyrylcholinesterase, Biochemistry, Acetylcholinesterase, Chromatography and Adduct.
Oksana Lockridge has included themes like Serine, Albumin, Stereochemistry, Peptide and Nerve agent in her Butyrylcholinesterase study.
Her study looks at the relationship between Stereochemistry and fields such as Active site, as well as how they intersect with chemical problems.
Her Nerve agent research includes themes of Sarin, Toxicity and Cholinesterase.
Her Acetylcholinesterase research includes elements of Affinity chromatography and Carboxylesterase.
Her Aché research incorporates themes from Internal medicine and Endocrinology.
Between 2011 and 2020, her most popular works were:
- Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure (67 citations)
- Naturally Occurring Genetic Variants of Human Acetylcholinesterase and Butyrylcholinesterase and Their Potential Impact on the Risk of Toxicity from Cholinesterase Inhibitors. (42 citations)
- Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and molecular dynamics studies (38 citations)
In her most recent research, the most cited papers focused on:
Her primary areas of investigation include Butyrylcholinesterase, Biochemistry, Enzyme, Acetylcholinesterase and Peptide.
Oksana Lockridge combines subjects such as Serine, Hydrolase, Paraoxon, Albumin and Stereochemistry with her study of Butyrylcholinesterase.
Her work carried out in the field of Enzyme brings together such families of science as Osmolyte and Point mutation.
The Acetylcholinesterase study combines topics in areas such as Pharmacology and Cholinesterase.
Her Cholinesterase research is multidisciplinary, relying on both Toxicity and Nerve agent.
Oksana Lockridge has researched Peptide in several fields, including Peptide sequence and Membrane protein.
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