H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 84 Citations 23,833 179 World Ranking 535 National Ranking 318
Medicine D-index 94 Citations 29,561 228 World Ranking 4846 National Ranking 2733

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

Lawrence B. Schwartz focuses on Tryptase, Mast cell, Immunology, Histamine and Molecular biology. Lawrence B. Schwartz combines subjects such as Systemic mastocytosis, Biochemistry, Pathology, Chymase and Antibody with his study of Tryptase. His research integrates issues of Endocrinology, Cell growth, Interleukin 5, Internal medicine and Basophil in his study of Mast cell.

His Immunology study is mostly concerned with Anaphylaxis, Allergy, Immunoglobulin E, Asthma and Allergen. His work deals with themes such as Allergic response, Lysosome, Bioavailability, Bronchoconstriction and Antihistamine, which intersect with Histamine. His Molecular biology study combines topics in areas such as Cell, Fibrinogenolysis, Plasmin, Proteases and Degranulation.

His most cited work include:

  • Evidence That Severe Asthma Can Be Divided Pathologically into Two Inflammatory Subtypes with Distinct Physiologic and Clinical Characteristics (980 citations)
  • Diagnostic criteria and classification of mastocytosis: a consensus proposal (853 citations)
  • Two types of human mast cells that have distinct neutral protease compositions. (823 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Immunology, Tryptase, Mast cell, Molecular biology and Histamine. His study in Allergy, Immunoglobulin E, Systemic mastocytosis, Asthma and Basophil falls under the purview of Immunology. His Tryptase research is multidisciplinary, relying on both Biochemistry, Anaphylaxis, Internal medicine, Chymase and Antibody.

His Mast cell research is multidisciplinary, incorporating perspectives in Stem cell factor, Cytokine, Pathology, Cell biology and Degranulation. The Molecular biology study combines topics in areas such as Complementary DNA and Cell culture. His Histamine research is multidisciplinary, incorporating elements of Bronchoalveolar lavage, Antigen and In vivo.

He most often published in these fields:

  • Immunology (48.04%)
  • Tryptase (47.49%)
  • Mast cell (39.39%)

What were the highlights of his more recent work (between 2015-2021)?

  • Immunology (48.04%)
  • Tryptase (47.49%)
  • Mast cell (39.39%)

In recent papers he was focusing on the following fields of study:

Lawrence B. Schwartz mostly deals with Immunology, Tryptase, Mast cell, Systemic mastocytosis and Anaphylaxis. His research in Tryptase intersects with topics in Humanized mouse, Immune system, Immunoglobulin E, Cell type and Allosteric regulation. His studies deal with areas such as Cancer research, TPSD1, Severe asthma and Mediator release as well as Mast cell.

His biological study spans a wide range of topics, including Mast cell activation syndrome, Mast cell activation and Dermatology. His studies deal with areas such as Prostaglandin D2, Perioperative, TPSB2 and Internal medicine as well as Anaphylaxis. His biological study spans a wide range of topics, including Allergen, Histamine and Somatic cell.

Between 2015 and 2021, his most popular works were:

  • Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology (138 citations)
  • Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number. (120 citations)
  • Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future (106 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

His scientific interests lie mostly in Immunology, Tryptase, Internal medicine, Systemic mastocytosis and Hereditary angioedema. Asthma, TPSAB1, Humanized mouse, Mast cell and Antigen presentation are subfields of Immunology in which his conducts study. His Mast cell research includes elements of Inflammation, Antibody and Biomarker.

His Tryptase research is multidisciplinary, relying on both Cell Degranulation, Degranulation, Mast cell homeostasis, Anaphylaxis and Allosteric regulation. The Observational study research he does as part of his general Internal medicine study is frequently linked to other disciplines of science, such as Emergency department, therefore creating a link between diverse domains of science. His Hereditary angioedema study integrates concerns from other disciplines, such as Angioedema, C1-inhibitor, Clinical trial, Adverse effect and Randomized controlled trial.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Evidence That Severe Asthma Can Be Divided Pathologically into Two Inflammatory Subtypes with Distinct Physiologic and Clinical Characteristics

Sally E. Wenzel;Lawrence B. Schwartz;Esther L. Langmack;Janet L. Halliday.
American Journal of Respiratory and Critical Care Medicine (1999)

1349 Citations

Two types of human mast cells that have distinct neutral protease compositions.

A A Irani;N M Schechter;S S Craig;G DeBlois.
Proceedings of the National Academy of Sciences of the United States of America (1986)

1294 Citations

Diagnostic criteria and classification of mastocytosis: a consensus proposal

Peter Valent;Hans P. Horny;Luis Escribano;B. Jack Longley.
Leukemia Research (2001)

1176 Citations

Tryptase Levels as an Indicator of Mast-Cell Activation in Systemic Anaphylaxis and Mastocytosis

Lawrence B. Schwartz;Dean D. Metcalfe;Jeffrey S. Miller;Harry Earl.
The New England Journal of Medicine (1987)

966 Citations

Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells.

L. B. Schwartz;A.-M. A. Irani;K. Roller;M. C. Castells.
Journal of Immunology (1987)

644 Citations

Time course of appearance and disappearance of human mast cell tryptase in the circulation after anaphylaxis.

L B Schwartz;J W Yunginger;J Miller;R Bokhari.
Journal of Clinical Investigation (1989)

577 Citations

Treatment of patients with the hypereosinophilic syndrome with mepolizumab

Marc E. Rothenberg;Amy D. Klion;Florence E. Roufosse;Jean Emmanuel Kahn.
The New England Journal of Medicine (2008)

559 Citations

Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor.

R J Blair;H Meng;M J Marchese;S Ren.
Journal of Clinical Investigation (1997)

546 Citations

Activation of Pulmonary Mast Cells by Bronchoalveolar Allergen Challenge: In Vivo Release of Histamine and Tryptase in Atopic Subjects with and without Asthma

Sally E. Wenzel;Alpha A. Fowler;Lawrence B. Schwartz.
The American review of respiratory disease (1988)

510 Citations

Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies.

Anne-Marie A. Irani;Timothy R. Bradford;Christopher L. Kepley;Norman M. Schechter.
Journal of Histochemistry and Cytochemistry (1989)

503 Citations

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Best Scientists Citing Lawrence B. Schwartz

Peter Valent

Peter Valent

Medical University of Vienna

Publications: 284

Dean D. Metcalfe

Dean D. Metcalfe

National Institutes of Health

Publications: 122

Cem Akin

Cem Akin

University of Michigan–Ann Arbor

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Sally E. Wenzel

Sally E. Wenzel

University of Pittsburgh

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Olivier Hermine

Olivier Hermine

Université Paris Cité

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Mariana Castells

Mariana Castells

Brigham and Women's Hospital

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Gunnar Nilsson

Gunnar Nilsson

Karolinska Institute

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Richard L. Stevens

Richard L. Stevens

Brigham and Women's Hospital

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Stephen J. Galli

Stephen J. Galli

Stanford University

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Luis Escribano

Luis Escribano

University of Salamanca

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Gunnar Pejler

Gunnar Pejler

Uppsala University

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Domenico Ribatti

Domenico Ribatti

University of Bari Aldo Moro

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Andrew F. Walls

Andrew F. Walls

University of Southampton

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Knut Brockow

Knut Brockow

Technical University of Munich

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William W. Busse

William W. Busse

University of Wisconsin–Madison

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George H. Caughey

George H. Caughey

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