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Immunology

D-Index
112
Citations
40723
World Ranking
459
National Ranking
280

Medicine

D-Index
115
Citations
41428
World Ranking
4603
National Ranking
2500

Overview

Lawrence B. Schwartz is affiliated with Virginia Commonwealth University in the United States. Their research focuses primarily on various aspects of medicine, with significant contributions in immunology and microbiology.

The main fields of study covered by their publications include:

  • Medicine
  • Immunology and Microbiology

Within these areas, Schwartz has explored several subfields, including:

  • Immunology
  • Immunology and Allergy
  • Physiology
  • Rheumatology
  • Pharmacology

Their work extensively addresses key topics related to allergic and immune responses, such as:

  • Mast cells and histamine
  • Asthma and respiratory diseases
  • Food Allergy and Anaphylaxis Research
  • Urticaria and Related Conditions
  • Allergic Rhinitis and Sensitization
  • Drug-Induced Adverse Reactions
  • Polyamine Metabolism and Applications

Recent significant papers authored or coauthored by Schwartz include:

  • Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal (2021, HemaSphere)
  • Heritable risk for severe anaphylaxis associated with increased α-tryptase-encoding germline copy number at TPSAB1 (2020, Journal of Allergy and Clinical Immunology)
  • Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts (2020, Theranostics)
  • Diagnosis, Classification and Management of Mast Cell Activation Syndromes (MCAS) in the Era of Personalized Medicine (2020, International Journal of Molecular Sciences)
  • Defining baseline variability of serum tryptase levels improves accuracy in identifying anaphylaxis (2021, Journal of Allergy and Clinical Immunology)

Schwartz has frequently published in the following venues:

  • The Journal of Allergy and Clinical Immunology In Practice (7 publications)
  • Journal of Allergy and Clinical Immunology (4 publications)
  • International Journal of Molecular Sciences (2 publications)
  • Annals of Allergy Asthma & Immunology (2 publications)
  • The Journal of Immunology (2 publications)

Frequent collaborators in Schwartz's research include:

  • Dean D. Metcalfe
  • Jonathan J. Lyons
  • Melody C. Carter
  • Patrizia Bonadonna
  • Peter Valent

Best Publications

  • Evidence That Severe Asthma Can Be Divided Pathologically into Two Inflammatory Subtypes with Distinct Physiologic and Clinical Characteristics

    Sally E. Wenzel;Lawrence B. Schwartz;Esther L. Langmack;Janet L. Halliday

  • Two types of human mast cells that have distinct neutral protease compositions.

    A A Irani;N M Schechter;S S Craig;G DeBlois

  • Diagnostic criteria and classification of mastocytosis: a consensus proposal

    Peter Valent;Hans P. Horny;Luis Escribano;B. Jack Longley

  • Tryptase Levels as an Indicator of Mast-Cell Activation in Systemic Anaphylaxis and Mastocytosis

    Lawrence B. Schwartz;Dean D. Metcalfe;Jeffrey S. Miller;Harry Earl

  • Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria.

    P. Valent;C. Akin;L. Escribano;M. Födinger

  • Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal

    Peter Valent;Cem Akin;Michel Arock;Knut Brockow

  • Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells.

    L. B. Schwartz;A.-M. A. Irani;K. Roller;M. C. Castells

  • Treatment of patients with the hypereosinophilic syndrome with mepolizumab

    Marc E. Rothenberg;Amy D. Klion;Florence E. Roufosse;Jean Emmanuel Kahn

  • Time course of appearance and disappearance of human mast cell tryptase in the circulation after anaphylaxis.

    L B Schwartz;J W Yunginger;J Miller;R Bokhari

  • Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor.

    R J Blair;H Meng;M J Marchese;S Ren

  • Diagnostic value of tryptase in anaphylaxis and mastocytosis.

    Lawrence B. Schwartz

  • Tryptase from human pulmonary mast cells. Purification and characterization.

    L B Schwartz;R A Lewis;K F Austen

  • Activation of Pulmonary Mast Cells by Bronchoalveolar Allergen Challenge: In Vivo Release of Histamine and Tryptase in Atopic Subjects with and without Asthma

    Sally E. Wenzel;Alpha A. Fowler;Lawrence B. Schwartz

  • Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies.

    Anne-Marie A. Irani;Timothy R. Bradford;Christopher L. Kepley;Norman M. Schechter

  • The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis.

    Lawrence B. Schwartz;Kentaro Sakai;Timothy R. Bradford;Shunlin Ren

  • Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation.

    Barry L. Gruber;Mary J. Marchese;Ko Suzuki;Lawrence B. Schwartz

  • Regulation of tryptase from human lung mast cells by heparin: stabilization of the active tetramer

    L B Schwartz;T R Bradford

  • Anaphylaxis in America: the prevalence and characteristics of anaphylaxis in the United States.

    Robert A. Wood;Carlos A. Camargo;Philip Lieberman;Hugh A. Sampson

  • Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells.

    L B Schwartz;R A Lewis;D Seldin;K F Austen

  • A common cold virus, rhinovirus 16, potentiates airway inflammation after segmental antigen bronchoprovocation in allergic subjects.

    William J. Calhoun;Elliot C. Dick;Lawrence B. Schwartz;William W. Busse

Frequent Co-Authors

Dean D. Metcalfe
Dean D. Metcalfe National Institute of Allergy and Infectious Diseases
Peter Valent
Peter Valent Medical University of Vienna
Cem Akin
Cem Akin University of Michigan–Ann Arbor
Mariana Castells
Mariana Castells Brigham and Women's Hospital
Karin Hartmann
Karin Hartmann University Hospital of Basel
Luis Escribano
Luis Escribano University of Salamanca
Massimo Triggiani
Massimo Triggiani University of Salerno
Knut Brockow
Knut Brockow Technical University of Munich
Burton Zweiman
Burton Zweiman University of Pennsylvania

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