Member of the Association of American Physicians
His scientific interests lie mostly in Immunology, Mast cell, Systemic mastocytosis, Molecular biology and Immunoglobulin E. His study looks at the relationship between Immunology and fields such as Internal medicine, as well as how they intersect with chemical problems. His Mast cell research includes elements of Stem cell factor, Degranulation, Histamine and Cell biology.
His Systemic mastocytosis course of study focuses on Myeloproliferative Disorders and Endomyocardial fibrosis. His study on Molecular biology also encompasses disciplines like
His primary areas of study are Mast cell, Immunology, Cell biology, Systemic mastocytosis and Degranulation. Dean D. Metcalfe has included themes like Stem cell factor, Pathology, Interleukin 33, Molecular biology and Histamine in his Mast cell study. His Stem cell factor research is multidisciplinary, incorporating perspectives in Cancer research and Cell growth.
His study in Receptor extends to Immunology with its themes. His studies deal with areas such as Inflammation, Chemotaxis and Cytokine as well as Cell biology. His study explores the link between Systemic mastocytosis and topics such as Urticaria pigmentosa that cross with problems in Diffuse cutaneous mastocytosis.
His primary areas of investigation include Immunology, Mast cell, Systemic mastocytosis, Cell biology and Tryptase. In his articles, Dean D. Metcalfe combines various disciplines, including Immunology and In patient. His Mast cell research includes elements of Cancer research, Stem cell factor, Cytokine and Allergy, Anaphylaxis.
As part of the same scientific family, Dean D. Metcalfe usually focuses on Systemic mastocytosis, concentrating on Urticaria pigmentosa and intersecting with Diffuse cutaneous mastocytosis and Telangiectasia macularis eruptiva perstans. His Cell biology research includes themes of Interleukin 33, Receptor, Degranulation and Mast. His work in Receptor addresses issues such as Immunoglobulin E, which are connected to fields such as Chemokine.
His scientific interests lie mostly in Immunology, Systemic mastocytosis, Mast cell, Tryptase and Internal medicine. The Immunology study combines topics in areas such as Signal transduction and Mast cell proliferation. In most of his Systemic mastocytosis studies, his work intersects topics such as Urticaria pigmentosa.
His study in Mast cell is interdisciplinary in nature, drawing from both Cancer research, Stem cell factor, Anaphylaxis, Degranulation and Histamine. His research investigates the connection between Degranulation and topics such as Cell biology that intersect with issues in CPA3. His Tryptase research is multidisciplinary, incorporating elements of Mast cell activation syndrome, Cell type and Bone marrow.
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IgE, Mast Cells, Basophils, and Eosinophils
Kelly D. Stone;Calman Prussin;Dean D. Metcalfe.
The Journal of Allergy and Clinical Immunology (2003)
Diagnostic criteria and classification of mastocytosis: a consensus proposal
Peter Valent;Hans P. Horny;Luis Escribano;B. Jack Longley.
Leukemia Research (2001)
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder
Hiroshi Nagata;Alexandra S. Worobec;Chad K. Oh;Badrul A. Chowdhury.
Proceedings of the National Academy of Sciences of the United States of America (1995)
Second Symposium on the Definition and Management of Anaphylaxis: Summary Report—Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network Symposium
Hugh A Sampson;Anne Muñoz-Furlong;Ronna L Campbell;N Franklin Adkinson.
Annals of Emergency Medicine (2006)
Double-blind, placebo-controlled food challenge (DBPCFC) as an office procedure: a manual.
S A Bock;H A Sampson;F M Atkins;R S Zeiger.
The Journal of Allergy and Clinical Immunology (1988)
Tryptase Levels as an Indicator of Mast-Cell Activation in Systemic Anaphylaxis and Mastocytosis
Lawrence B. Schwartz;Dean D. Metcalfe;Jeffrey S. Miller;Harry Earl.
The New England Journal of Medicine (1987)
Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria.
P. Valent;C. Akin;L. Escribano;M. Födinger.
European Journal of Clinical Investigation (2007)
Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis
B. Jack Longley;B. Jack Longley;Dean D. Metcalfe;Michael Tharp;Xiaomei Wang.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies.
Calman Prussin;Dean D. Metcalfe.
Journal of Immunological Methods (1995)
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcεRI or FcγRI
Arnold S. Kirshenbaum;Cem Akin;Yalin Wu;Menachem Rottem.
Leukemia Research (2003)
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