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Materials Science

D-Index
87
Citations
33612
World Ranking
1928
National Ranking
583

Research.com Recognitions

  • 2014 - Fellow, National Academy of Inventors

Overview

Justin Hanes is affiliated with Johns Hopkins University in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with particular emphasis on molecular biology, radiology, nuclear medicine and imaging, ophthalmology, public health, environmental and occupational health, and pulmonary and respiratory medicine.

The scientist's main topics of work include ocular surface and contact lens studies, corneal surgery and treatments, glaucoma and retinal disorders, retinal development and disorders, retinal diseases and treatments, advanced drug delivery systems, and RNA interference and gene delivery.

Justin Hanes has contributed to several papers focused on drug delivery, ocular health, and molecular medicine. Notable recent publications include:

  • "Gelling hypotonic polymer solution for extended topical drug delivery to the eye" (2020) published in Nature Biomedical Engineering
  • "Augmentation of brain tumor interstitial flow via focused ultrasound promotes brain-penetrating nanoparticle dispersion and transfection" (2020) published in Science Advances
  • "Avoiding a Sticky Situation: Bypassing the Mucus Barrier for Improved Local Drug Delivery" (2021) published in Trends in Molecular Medicine
  • "Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles" (2020) published in Nature Communications
  • "The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis" (2020) published in PLoS Pathogens

Frequent co-authors of Justin Hanes include Laura M. Ensign, Jung Soo Suk, Nicole M. Anders, Charles G. Eberhart, and Henry T. Hsueh.

The scientist has published extensively in venues such as UNC Libraries, Bioengineering & Translational Medicine, Drug Delivery and Translational Research, Science Advances, and Nature Communications.

Justin Hanes was recognized as a Fellow of the National Academy of Inventors in 2014.

Best Publications

  • PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

    Jung Soo Suk;Qingguo Xu;Namho Kim;Justin Hanes

  • Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues.

    Samuel K. Lai;Ying Ying Wang;Justin Hanes

  • Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers.

    Laura M. Ensign;Richard Cone;Richard Cone;Justin Hanes

  • Large Porous Particles for Pulmonary Drug Delivery

    David A. Edwards;Justin Hanes;Giovanni Caponetti;Jeffrey Hrkach

  • Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus

    Samuel K. Lai;D. Elizabeth O'Hanlon;Suzanne Harrold;Stan T. Man

  • Aerodynamically light particles for pulmonary drug delivery

    David A. Edwards;Giovannia Caponetti;Jeffrey S. Hrkach;Noah Lotan

  • Addressing the PEG Mucoadhesivity Paradox to Engineer Nanoparticles that “Slip” through the Human Mucus Barrier

    Ying Ying Wang;Samuel K. Lai;Jung Soo Suk;Amanda Pace

  • A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue

    Elizabeth A. Nance;Graeme F. Woodworth;Kurt A. Sailor;Ting Yu Shih

  • Preparation of particles for inhalation

    David A. Edwards;Justin Hanes;Carmen Evora;Robert S. Langer

  • Particles incorporating surfactants for pulmonary drug delivery

    Justin Hanes;David A. Edwards;Carmen Evora;Robert Langer

  • Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo.

    Qingguo Xu;Laura M. Ensign;Laura M. Ensign;Nicholas J. Boylan;Arne Schön

  • Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.

    Benjamin C. Tang;Michelle Dawson;Michelle Dawson;Samuel K. Lai;Ying Ying Wang

  • A Theoretical Model of Erosion and Macromolecular Drug Release from Biodegrading Microspheres

    Richard P. Batycky;Justin Hanes;Robert Langer;David A. Edwards

  • Nanoparticles for oral delivery: Design, evaluation and state-of-the-art.

    Abhijit A. Date;Justin Hanes;Laura M. Ensign;Laura M. Ensign

  • Efficient active transport of gene nanocarriers to the cell nucleus

    Junghae Suh;Denis Wirtz;Justin Hanes

  • Nanoparticle diffusion in respiratory mucus from humans without lung disease

    Benjamin S. Schuster;Jung Soo Suk;Graeme F. Woodworth;Justin Hanes

  • Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses

    Samuel K. Lai;Ying Ying Wang;Kaoru Hida;Richard Cone

  • The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.

    Jung Soo Suk;Samuel K. Lai;Ying Ying Wang;Laura M. Ensign

  • Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse.

    Katharina Maisel;Laura Ensign;Mihika Reddy;Richard Cone

  • Mucus-Penetrating Nanoparticles for Vaginal Drug Delivery Protect Against Herpes Simplex Virus

    Laura M. Ensign;Benjamin C. Tang;Benjamin C. Tang;Ying Ying Wang;Terence A. Tse;Terence A. Tse

  • Enhanced Viscoelasticity of Human Cystic Fibrotic Sputum Correlates with Increasing Microheterogeneity in Particle Transport

    Michelle Dawson;Denis Wirtz;Justin Hanes

Frequent Co-Authors

Charles G. Eberhart
Charles G. Eberhart Johns Hopkins University School of Medicine
Denis Wirtz
Denis Wirtz Johns Hopkins University
Peter A. Campochiaro
Peter A. Campochiaro Johns Hopkins University School of Medicine
Harry A. Quigley
Harry A. Quigley Johns Hopkins University
Henry Brem
Henry Brem Johns Hopkins University School of Medicine
Donald J. Zack
Donald J. Zack Johns Hopkins University School of Medicine
Hai-Quan Mao
Hai-Quan Mao Johns Hopkins University
Steven M. Rowe
Steven M. Rowe University of Alabama at Birmingham
Alexander L. Klibanov
Alexander L. Klibanov University of Virginia

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