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Joshua D. Rabinowitz

Joshua D. Rabinowitz

D-Index & Metrics

Biology and Biochemistry

D-Index
138
Citations
80984
World Ranking
294
National Ranking
200

Research.com Recognitions

  • 2016 - National Institutes of Health Director's Pioneer Award

Overview

Joshua D. Rabinowitz is affiliated with Princeton University in the United States and conducts research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work encompasses several subfields including Molecular Biology, Physiology, Cancer Research, Immunology, and Oncology.

Their research covers a range of topics, notably:

  • Cancer, Hypoxia, and Metabolism
  • Diet and metabolism studies
  • Mitochondrial Function and Pathology
  • Adipose Tissue and Metabolism
  • Metabolomics and Mass Spectrometry Studies
  • Microbial Metabolic Engineering and Bioproduction
  • RNA modifications and cancer

Joshua D. Rabinowitz has published extensively in several venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Metabolism
  • Cancer Research
  • Nature Metabolism
  • Cell

Among their recent papers are:

  • "Lactate: the ugly duckling of energy metabolism", 2020, published in Nature Metabolism
  • "Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity", 2020, published in Cell
  • "Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate", 2020, published in Nature
  • "Comprehensive quantification of fuel use by the failing and nonfailing human heart", 2020, published in Science
  • "Restoring metabolism of myeloid cells reverses cognitive decline in ageing", 2021, published in Nature

The scientist frequently collaborates with several coauthors, including:

  • Wenyun Lu
  • Cholsoon Jang
  • Melanie R. McReynolds
  • Yihui Shen
  • Won Dong Lee

In recognition of their research contributions, Joshua D. Rabinowitz was awarded the National Institutes of Health Director's Pioneer Award in 2016.

Best Publications

  • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

    Lenny Dang;David W. White;Stefan Gross;Bryson D. Bennett

  • The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

    Patrick S. Ward;Jay Patel;David R. Wise;Omar Abdel-Wahab

  • Autophagy and metabolism.

    Joshua D. Rabinowitz;Eileen White;Eileen White

  • Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

    Bryson D Bennett;Elizabeth H Kimball;Melissa Gao;Robin Osterhout

  • Glucose feeds the TCA cycle via circulating lactate.

    Sheng Hui;Jonathan M. Ghergurovich;Raphael J. Morscher;Cholsoon Jang

  • One-Carbon Metabolism in Health and Disease

    Gregory S. Ducker;Joshua D. Rabinowitz

  • Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

    Cosimo Commisso;Shawn M. Davidson;Rengin G. Soydaner-Azeloglu;Seth J. Parker

  • Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

    Jessie Yanxiang Guo;Hsin Yi Chen;Robin Mathew;Jing Fan

  • The return of metabolism: biochemistry and physiology of the pentose phosphate pathway

    Anna Stincone;Alessandro Prigione;Thorsten Cramer;Mirjam M.C. Wamelink

  • Mitochondria and Cancer

    Wei-Xing Zong;Joshua D. Rabinowitz;Eileen White

  • Quantitative flux analysis reveals folate-dependent NADPH production

    Jing-Jing Fan;Jiangbin Ye;Jurre J Kamphorst;Tomer Shlomi

  • Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein

    Jurre J. Kamphorst;Michel Nofal;Cosimo Commisso;Sean R. Hackett

  • Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells

    Matthew G. Vander Heiden;Matthew G. Vander Heiden;Jason W. Locasale;Jason W. Locasale;Kenneth D. Swanson;Hadar Sharfi

  • Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry.

    Sunil U. Bajad;Wenyun Lu;Elizabeth H. Kimball;Jie Yuan

  • Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

    Joshua Munger;Bryson D Bennett;Anuraag Parikh;Xiao-Jiang Feng

  • Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

    Jurre J. Kamphorst;Justin R. Cross;Jing Fan;Elisa de Stanchina

  • A roadmap for interpreting 13 C metabolite labeling patterns from cells

    Joerg M. Buescher;Maciek R. Antoniewicz;Laszlo G. Boros;Shawn C Burgess

  • Metabolomics and Isotope Tracing

    Cholsoon Jang;Li Chen;Joshua D. Rabinowitz

  • Metabolomic analysis and visualization engine for LC-MS data.

    Eugene Melamud;Livia Vastag;Joshua D. Rabinowitz

  • Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

    Jessie Yanxiang Guo;Gizem Karsli-Uzunbas;Robin Mathew;Seena C. Aisner

Frequent Co-Authors

Wenyun Lu
Wenyun Lu Princeton University
Eileen White
Eileen White Rutgers, The State University of New Jersey
Ling Liu
Ling Liu Georgia Institute of Technology
Herschel Rabitz
Herschel Rabitz Princeton University
Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Thomas Shenk
Thomas Shenk Princeton University
Harden M. McConnell
Harden M. McConnell Stanford University
Joseph A. Baur
Joseph A. Baur University of Pennsylvania
David Botstein
David Botstein Princeton University

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