The scientist’s investigation covers issues in Biochemistry, Cell biology, Cancer research, Metabolism and Glycolysis. His studies deal with areas such as Chromatin, Gene, Glutamine and Cell growth as well as Cell biology. Jason W. Locasale combines subjects such as Autophagy, Metastasis and Mitochondrion with his study of Cancer research.
His work carried out in the field of Metabolism brings together such families of science as Cancer, Carbohydrate metabolism, Immunology and Adenosine triphosphate. His research links Cancer cell with Glycolysis. The study incorporates disciplines such as Oxidative stress, Reactive oxygen species, Pancreatic cancer and Intracellular in addition to Pentose phosphate pathway.
Cell biology, Biochemistry, Metabolism, Cancer research and Glycolysis are his primary areas of study. His Cell biology study integrates concerns from other disciplines, such as Epigenetics, Cell growth and Pentose phosphate pathway. His Biochemistry study frequently draws connections to other fields, such as Cancer cell.
His study explores the link between Metabolism and topics such as Metabolomics that cross with problems in Colorectal cancer. As a part of the same scientific family, he mostly works in the field of Cancer research, focusing on Cancer and, on occasion, Metformin. His Glycolysis research is multidisciplinary, incorporating perspectives in Carbohydrate metabolism and Oxidative phosphorylation.
Jason W. Locasale spends much of his time researching Cell biology, Metabolism, Chromatin, Carbohydrate metabolism and Cancer research. His Cell biology study incorporates themes from Epigenomics, Protein subunit and Downregulation and upregulation. The subject of his Metabolism research is within the realm of Biochemistry.
His work carried out in the field of Biochemistry brings together such families of science as Cell culture and In vivo. Jason W. Locasale has included themes like Oxidative stress and Epigenetics in his Chromatin study. His work deals with themes such as Cancer, Breast cancer, Immune system, Single-cell analysis and Metabolite, which intersect with Cancer research.
His primary areas of study are Cell biology, Metabolism, Carbohydrate metabolism, Biochemistry and Histone. His biological study spans a wide range of topics, including Epigenomics, Cancer metabolism, Metabolic network and Malignant cells. His Metabolism study combines topics in areas such as Autophagy, Gut flora, Serine, Cell growth and Cancer cell.
His Carbohydrate metabolism research incorporates themes from Tricarboxylic acid, Citric acid cycle, Warburg effect, Systems biology and Quantitative analysis. In his work, Chromatin and Epigenetics is strongly intertwined with Cellular homeostasis, which is a subfield of Histone. Jason W. Locasale focuses mostly in the field of Chromatin, narrowing it down to topics relating to Tumor progression and, in certain cases, Cancer research.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V. Liberti;Jason W. Locasale.
Trends in Biochemical Sciences (2016)
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
Haoqiang Ying;Alec C. Kimmelman;Costas A. Lyssiotis;Sujun Hua.
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou;Dimitrios Anastasiou;George Poulogiannis;George Poulogiannis;John M. Asara;John M. Asara;Matthew B. Boxer.
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
Jason W. Locasale;Alexandra R. Grassian;Tamar Melman;Costas A. Lyssiotis.
Nature Genetics (2011)
Serine, glycine and one-carbon units: cancer metabolism in full circle
Jason W. Locasale.
Nature Reviews Cancer (2013)
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron.
Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
Matthew G. Vander Heiden;Matthew G. Vander Heiden;Jason W. Locasale;Jason W. Locasale;Kenneth D. Swanson;Hadar Sharfi.
Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation
Ng Shyh-Chang;Jason W. Locasale;Jason W. Locasale;Costas A. Lyssiotis;Costas A. Lyssiotis;Yuxiang Zheng.
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
Valerie A. Gerriets;Rigel J. Kishton;Amanda G. Nichols;Andrew N. Macintyre.
Journal of Clinical Investigation (2015)
A roadmap for interpreting 13 C metabolite labeling patterns from cells
Joerg M. Buescher;Maciek R. Antoniewicz;Laszlo G. Boros;Shawn C Burgess.
Current Opinion in Biotechnology (2015)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: