World's Best Scientists 2026 revealed!
Jason W. Locasale

Jason W. Locasale

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
45050
World Ranking
1869
National Ranking
1027

Jason W. Locasale publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Jason W. Locasale sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 307 publications — 79th percentile

79% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Jason W. Locasale D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jason W. Locasale sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 95 D-Index — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Jason W. Locasale is affiliated with Duke University in the United States. Their research spans multiple fields and subfields predominantly within biochemistry, genetics, molecular biology, and medicine. The focus areas include molecular biology, cancer research, immunology, physiology, and pulmonary and respiratory medicine.

The scientist's work covers several main topics, highlighting a broad engagement with cancer-related metabolism and epigenetics. These topics include:

  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • Metabolomics and Mass Spectrometry Studies
  • RNA modifications and cancer
  • Diet and metabolism studies
  • Immune cells in cancer
  • Metabolism, Diabetes, and Cancer

Jason W. Locasale has contributed extensively to the literature, with some recent publications as follows:

  • "Metabolomics in cancer research and emerging applications in clinical oncology," 2021, CA A Cancer Journal for Clinicians
  • "Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion," 2020, Nature Immunology
  • "The evolving metabolic landscape of chromatin biology and epigenetics," 2020, Nature Reviews Genetics
  • "Embracing cancer complexity: Hallmarks of systemic disease," 2024, Cell
  • "Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing," 2020, Nature Cell Biology

The frequent coauthors with whom Jason W. Locasale has collaborated include Juan Liu, Xiaojing Liu, Ziwei Dai, Navdeep S. Chandel, and Annamarie E. Allen. This collaborative network reflects a focus on interdisciplinary research across cancer biology and metabolism.

The most common publication venues for their work feature high-impact journals and repositories such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • UNC Libraries
  • Nature Communications
  • Nature Metabolism

Through a broad range of scholarly output and collaboration, Jason W. Locasale's scientific contributions address complex questions related to cancer metabolism, epigenetics, immunology, and related physiological processes.

Best Publications

  • The Warburg Effect: How Does it Benefit Cancer Cells?

    Maria V. Liberti;Jason W. Locasale

  • Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

    Haoqiang Ying;Alec C. Kimmelman;Costas A. Lyssiotis;Sujun Hua

  • Serine, glycine and one-carbon units: cancer metabolism in full circle

    Jason W. Locasale

  • Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

    Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron

  • Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

    Jason W. Locasale;Alexandra R. Grassian;Tamar Melman;Costas A. Lyssiotis

  • Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

    Dimitrios Anastasiou;Dimitrios Anastasiou;George Poulogiannis;George Poulogiannis;John M. Asara;John M. Asara;Matthew B. Boxer

  • Glutamine Metabolism in Cancer: Understanding the Heterogeneity.

    Ahmad A. Cluntun;Michael J. Lukey;Richard A. Cerione;Jason W. Locasale

  • Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells

    Matthew G. Vander Heiden;Matthew G. Vander Heiden;Jason W. Locasale;Jason W. Locasale;Kenneth D. Swanson;Hadar Sharfi

  • Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

    Valerie A. Gerriets;Rigel J. Kishton;Amanda G. Nichols;Andrew N. Macintyre

  • A roadmap for interpreting 13 C metabolite labeling patterns from cells

    Joerg M. Buescher;Maciek R. Antoniewicz;Laszlo G. Boros;Shawn C Burgess

  • Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.

    Marc O. Johnson;Marc O. Johnson;Melissa M. Wolf;Matthew Z. Madden;Gabriela Andrejeva

  • Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

    Ng Shyh-Chang;Jason W. Locasale;Jason W. Locasale;Costas A. Lyssiotis;Costas A. Lyssiotis;Yuxiang Zheng

  • Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

    Samantha J. Mentch;Mahya Mehrmohamadi;Lei Huang;Xiaojing Liu

  • Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression

    Valerie A Gerriets;Rigel J Kishton;Marc O Johnson;Marc O Johnson;Sivan Cohen

  • Dietary methionine influences therapy in mouse cancer models and alters human metabolism

    Xia Gao;Sydney M. Sanderson;Ziwei Dai;Michael A. Reid

  • Metabolic Flux and the Regulation of Mammalian Cell Growth

    Jason W. Locasale;Lewis C. Cantley;Lewis C. Cantley

  • Metabolomics in cancer research and emerging applications in clinical oncology.

    Daniel R. Schmidt;Daniel R. Schmidt;Rutulkumar Patel;David G. Kirsch;Caroline A. Lewis

  • The impact of cellular metabolism on chromatin dynamics and epigenetics.

    Michael A. Reid;Ziwei Dai;Jason W. Locasale

  • Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

    Matthew G. Vander Heiden;Dimitrios Anastasiou;George Poulogiannis;John M. Asara

  • Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

    J. Locasale;J. Locasale;Alexandra Grassian;Rameen Beroukhim;Matthew Langer Meyerson

Frequent Co-Authors

Lewis C. Cantley
Lewis C. Cantley Harvard University
John M. Asara
John M. Asara Beth Israel Deaconess Medical Center
Jeffrey C. Rathmell
Jeffrey C. Rathmell Vanderbilt University Medical Center
Atsuo T. Sasaki
Atsuo T. Sasaki University of Cincinnati
Matthew D. Hirschey
Matthew D. Hirschey Duke University
Costas A. Lyssiotis
Costas A. Lyssiotis University of Michigan–Ann Arbor
Jihye Paik
Jihye Paik Cornell University
Gerhard Wagner
Gerhard Wagner Harvard University
Ernst Lengyel
Ernst Lengyel University of Chicago

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