D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 78 Citations 25,948 250 World Ranking 2811 National Ranking 1489

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

The scientist’s investigation covers issues in Biochemistry, Cell biology, Cancer research, Metabolism and Glycolysis. His studies deal with areas such as Chromatin, Gene, Glutamine and Cell growth as well as Cell biology. Jason W. Locasale combines subjects such as Autophagy, Metastasis and Mitochondrion with his study of Cancer research.

His work carried out in the field of Metabolism brings together such families of science as Cancer, Carbohydrate metabolism, Immunology and Adenosine triphosphate. His research links Cancer cell with Glycolysis. The study incorporates disciplines such as Oxidative stress, Reactive oxygen species, Pancreatic cancer and Intracellular in addition to Pentose phosphate pathway.

His most cited work include:

  • The Warburg Effect: How Does it Benefit Cancer Cells? (1224 citations)
  • Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism (1075 citations)
  • Serine, glycine and one-carbon units: cancer metabolism in full circle (790 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, Biochemistry, Metabolism, Cancer research and Glycolysis are his primary areas of study. His Cell biology study integrates concerns from other disciplines, such as Epigenetics, Cell growth and Pentose phosphate pathway. His Biochemistry study frequently draws connections to other fields, such as Cancer cell.

His study explores the link between Metabolism and topics such as Metabolomics that cross with problems in Colorectal cancer. As a part of the same scientific family, he mostly works in the field of Cancer research, focusing on Cancer and, on occasion, Metformin. His Glycolysis research is multidisciplinary, incorporating perspectives in Carbohydrate metabolism and Oxidative phosphorylation.

He most often published in these fields:

  • Cell biology (36.82%)
  • Biochemistry (37.91%)
  • Metabolism (26.71%)

What were the highlights of his more recent work (between 2019-2021)?

  • Cell biology (36.82%)
  • Metabolism (26.71%)
  • Chromatin (7.58%)

In recent papers he was focusing on the following fields of study:

Jason W. Locasale spends much of his time researching Cell biology, Metabolism, Chromatin, Carbohydrate metabolism and Cancer research. His Cell biology study incorporates themes from Epigenomics, Protein subunit and Downregulation and upregulation. The subject of his Metabolism research is within the realm of Biochemistry.

His work carried out in the field of Biochemistry brings together such families of science as Cell culture and In vivo. Jason W. Locasale has included themes like Oxidative stress and Epigenetics in his Chromatin study. His work deals with themes such as Cancer, Breast cancer, Immune system, Single-cell analysis and Metabolite, which intersect with Cancer research.

Between 2019 and 2021, his most popular works were:

  • Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing. (35 citations)
  • Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway. (28 citations)
  • Disturbed mitochondrial dynamics in CD8 + TILs reinforce T cell exhaustion (26 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

His primary areas of study are Cell biology, Metabolism, Carbohydrate metabolism, Biochemistry and Histone. His biological study spans a wide range of topics, including Epigenomics, Cancer metabolism, Metabolic network and Malignant cells. His Metabolism study combines topics in areas such as Autophagy, Gut flora, Serine, Cell growth and Cancer cell.

His Carbohydrate metabolism research incorporates themes from Tricarboxylic acid, Citric acid cycle, Warburg effect, Systems biology and Quantitative analysis. In his work, Chromatin and Epigenetics is strongly intertwined with Cellular homeostasis, which is a subfield of Histone. Jason W. Locasale focuses mostly in the field of Chromatin, narrowing it down to topics relating to Tumor progression and, in certain cases, Cancer research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Warburg Effect: How Does it Benefit Cancer Cells?

Maria V. Liberti;Jason W. Locasale.
Trends in Biochemical Sciences (2016)

1775 Citations

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

Haoqiang Ying;Alec C. Kimmelman;Costas A. Lyssiotis;Sujun Hua.
Cell (2012)

1604 Citations

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

Dimitrios Anastasiou;Dimitrios Anastasiou;George Poulogiannis;George Poulogiannis;John M. Asara;John M. Asara;Matthew B. Boxer.
Science (2011)

1065 Citations

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Jason W. Locasale;Alexandra R. Grassian;Tamar Melman;Costas A. Lyssiotis.
Nature Genetics (2011)

1025 Citations

Serine, glycine and one-carbon units: cancer metabolism in full circle

Jason W. Locasale.
Nature Reviews Cancer (2013)

1023 Citations

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron.
Cell (2015)

944 Citations

Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells

Matthew G. Vander Heiden;Matthew G. Vander Heiden;Jason W. Locasale;Jason W. Locasale;Kenneth D. Swanson;Hadar Sharfi.
Science (2010)

687 Citations

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

Ng Shyh-Chang;Jason W. Locasale;Jason W. Locasale;Costas A. Lyssiotis;Costas A. Lyssiotis;Yuxiang Zheng.
Science (2013)

553 Citations

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

Valerie A. Gerriets;Rigel J. Kishton;Amanda G. Nichols;Andrew N. Macintyre.
Journal of Clinical Investigation (2015)

511 Citations

A roadmap for interpreting 13 C metabolite labeling patterns from cells

Joerg M. Buescher;Maciek R. Antoniewicz;Laszlo G. Boros;Shawn C Burgess.
Current Opinion in Biotechnology (2015)

488 Citations

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