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Genetics

D-Index
43
Citations
47741
World Ranking
4267
National Ranking
1840

Overview

Lee Rowen is affiliated with the Institute for Systems Biology in Seattle, United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, focusing on understanding disease mechanisms and immune responses.

Rowen's main fields of study include Medicine and Biochemistry, Genetics and Molecular Biology. Within these, their subfields encompass Molecular Biology, Neurology, Biological Psychiatry, Genetics, and Infectious Diseases. Their work particularly addresses the long-term effects of COVID-19, tryptophan and brain disorders, single-cell and spatial transcriptomics, inflammasome and immune disorders, diabetes and associated disorders, COVID-19 clinical research studies, and intensive care unit cognitive disorders.

Frequent coauthors collaborating with Lee Rowen are:

  • Yapeng Su
  • Dan Yuan
  • Daniel Chen
  • Jongchan Choi
  • Sarah Li

Their publication history features venues such as Cell, bioRxiv (Cold Spring Harbor Laboratory), and Nature. Two papers appeared in Cell, two in bioRxiv, and one in Nature.

Recent notable papers authored or co-authored by Rowen include:

  • Multiple early factors anticipate post-acute COVID-19 sequelae, 2022, Cell
  • Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19, 2020, Cell
  • Heterogeneous immunological recovery trajectories revealed in post-acute COVID-19, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • Publisher Correction: The DNA sequence and analysis of human chromosome 14, 2023, Nature
  • Whole-Proteome Screening and Multi-Modal Profiling of Antigen-Specific CD4+ T Cells at Single-Cell Resolution, 2025, bioRxiv (Cold Spring Harbor Laboratory)

The topics frequently addressed in their publications reflect a focus on immune response dynamics, post-viral syndromes especially related to COVID-19, molecular and cellular profiling technologies, and biochemical pathways related to brain disorders and immune system regulation.

Best Publications

  • Initial sequencing and analysis of the human genome.

    Eric S. Lander;Lauren M. Linton;Bruce Birren;Chad Nusbaum

  • Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes

    Samuel Aparicio;Jarrod Chapman;Elia Stupka;Nik Putnam

  • A Genomic Regulatory Network for Development

    Eric H. Davidson;Jonathan P. Rast;Paola Oliveri;Andrew Ransick

  • Complete sequence and gene map of a human major histocompatibility complex

    S Beck;D Geraghty;H Inoko;L Rowen

  • The evolution of vertebrate Toll-like receptors

    Jared C. Roach;Gustavo Glusman;Lee Rowen;Amardeep Kaur

  • Analysis of genetic inheritance in a family quartet by whole-genome sequencing

    Jared C. Roach;Gustavo Glusman;Arian F. A. Smit;Chad D. Huff;Chad D. Huff

  • A physical map of the human genome.

    John Douglas Mcpherson;Marco Marra;Marco Marra;La Deana Hillier;Robert H. Waterston

  • The Complete 685-Kilobase DNA Sequence of the Human β T Cell Receptor Locus

    Lee Rowen;Ben F. Koop;Leroy Hood

  • Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.

    Yapeng Su;Daniel Chen;Dan Yuan;Christopher Lausted

  • An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

    Catherine A. Brownstein;Alan H. Beggs;Nils Homer;Barry Merriman

  • A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo.

    Eric H. Davidson;Jonathan P. Rast;Paola Oliveri;Andrew Ransick

  • Integration of cytogenetic landmarks into the draft sequence of the human genome

    V. G. Cheung;N. Nowak;W. Jang;I. R. Kirsch

  • Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chains.

    L. Rowen;A. Kornberg

  • The Human Genome Project: big science transforms biology and medicine

    Leroy Hood;Lee Rowen

  • Majority of divergence between closely related DNA samples is due to indels

    Roy J. Britten;Lee Rowen;John Williams;R. Andrew Cameron

  • Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes

    Barbara J. Trask;Cynthia Friedman;Antonia Martin-Gallardo;Lee Rowen

  • Genetic Divergence of the Rhesus Macaque Major Histocompatibility Complex

    Riza Daza-Vamenta;Gustavo Glusman;Lee Rowen;Brandon Guthrie

  • Analysis of the Human Neurexin Genes: Alternative Splicing and the Generation of Protein Diversity

    Lee Rowen;Janet Young;Brian Birditt;Amardeep Kaur

  • The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA.

    Ben F. Koop;Lee Rowen;Kai Wang;Chia Lam Kuo

  • Comparative genomics of the human and mouse T cell receptor loci.

    Gustavo Glusman;Lee Rowen;Inyoul Lee;Cecilie Boysen

Frequent Co-Authors

Leroy Hood
Leroy Hood University of Washington
Gwênlyn Glusman
Gwênlyn Glusman Institute for Systems Biology
Barbara J. Trask
Barbara J. Trask Fred Hutchinson Cancer Research Center
Arthur Kornberg
Arthur Kornberg Stanford University
Norman A. Doggett
Norman A. Doggett Los Alamos National Laboratory
Kai Wang
Kai Wang Hebei University
Stephan Beck
Stephan Beck University College London
Marco A. Marra
Marco A. Marra University of British Columbia
Evan E. Eichler
Evan E. Eichler University of Washington
Richard K. Wilson
Richard K. Wilson Nationwide Children's Hospital

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