What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Cytokine
His primary scientific interests are in Cell biology, Signal transduction, PI3K/AKT/mTOR pathway, Immune system and T cell.
His studies deal with areas such as CD28, Transcription factor, Immunology and Cellular differentiation as well as Cell biology.
Within one scientific family, Hongbo Chi focuses on topics pertaining to Priming under Cellular differentiation, and may sometimes address concerns connected to Lymphocyte.
His Signal transduction study integrates concerns from other disciplines, such as Sphingosine, Receptor, Caspase 1, Kinase and Mitophagy.
His PI3K/AKT/mTOR pathway research focuses on Immune tolerance and how it relates to Regulatory T cell.
His biological study spans a wide range of topics, including Acquired immune system, Neuroinflammation, Interleukin 17 and Cell fate determination.
His most cited work include:
- The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. (1099 citations)
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells (1027 citations)
- Regulation and function of mTOR signalling in T cell fate decisions (484 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Cell biology, T cell, Immune system, Signal transduction and Immunology.
His Cell biology research is multidisciplinary, incorporating perspectives in Transcription factor and Cellular differentiation.
His studies examine the connections between T cell and genetics, as well as such issues in Acquired immune system, with regards to Dendritic cell.
His study in Immune system is interdisciplinary in nature, drawing from both Cancer research, Lymphocyte and Function.
His research integrates issues of Kinase and Cell growth in his study of Signal transduction.
Hongbo Chi has included themes like Regulatory T cell and Immune tolerance in his PI3K/AKT/mTOR pathway study.
He most often published in these fields:
- Cell biology (69.28%)
- T cell (33.33%)
- Immune system (30.72%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (69.28%)
- T cell (33.33%)
- Effector (14.38%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cell biology, T cell, Effector, Immune system and Acquired immune system.
His work on Cell biology is being expanded to include thematically relevant topics such as Transcription factor.
The concepts of his T cell study are interwoven with issues in Targeted therapy, Leukemia, Homeostasis and BATF.
His research on Effector also deals with topics like
- T-cell receptor and related Immune tolerance, Serine and Cytokine,
- Amino acid and related RHEB, Priming, Intracellular and Sense.
His study on Systems immunology is often connected to Metabolic control analysis as part of broader study in Immune system.
His research investigates the connection between PI3K/AKT/mTOR pathway and topics such as Cellular differentiation that intersect with problems in Cell Maintenance and Dendritic cell.
Between 2018 and 2021, his most popular works were:
- Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression (89 citations)
- Metabolic coordination of T cell quiescence and activation. (88 citations)
- Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy (72 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Cytokine
Hongbo Chi mainly investigates Cell biology, T cell, Effector, Immune system and Acquired immune system.
Hongbo Chi is involved in the study of Cell biology that focuses on mTORC1 in particular.
He studied T cell and PI3K/AKT/mTOR pathway that intersect with Kinase.
His Effector study combines topics from a wide range of disciplines, such as Receptor, Cell therapy, BATF, T-cell receptor and Immunotherapy.
In his work, Cellular differentiation, Dendritic cell, Regulatory T cell, Cell metabolism and Regulator is strongly intertwined with Signal transduction, which is a subfield of Immune system.
His studies in Acquired immune system integrate themes in fields like Cellular metabolism, Transcriptional Networks, Neuroscience and Systems biology.
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