World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
59
Citations
15983
World Ranking
3228
National Ranking
1275

Overview

Demin Wang is affiliated with the Medical College of Wisconsin in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans multiple subfields including Hematology, Molecular Biology, Immunology, Surgery, and Oncology.

Their work focuses primarily on topics such as Platelet Disorders and Treatments, Heparin-Induced Thrombocytopenia and Thrombosis, Multiple Myeloma Research and Treatments, Cell Adhesion Molecules Research, Protein Degradation and Inhibitors, Immune Cell Function and Interaction, and T-cell and B-cell Immunology.

Demin Wang has published numerous papers in several prominent venues. Frequent publication venues include:

  • Blood
  • Leukemia
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife

Recent papers authored or co-authored by Wang include:

  • Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation, 2020, Proceedings of the National Academy of Sciences
  • Monoclonal and oligoclonal anti-platelet factor 4 antibodies mediate VITT, 2022, Blood
  • Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment, 2020, Leukemia
  • Expression of Nras Q61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice, 2020, Blood
  • Monoclonal gammopathy of thrombotic/thrombocytopenic significance, 2023, Blood

Collaborations feature numerous frequent co-authors, indicating a broad network of research partnerships. Notable frequent co-authors include:

  • Renren Wen
  • Yongwei Zheng
  • Mei Yu
  • Jing Zhang
  • Yun Zhou

Their research contributions cover complex aspects of platelet biology and related disorders, as well as malignancies such as multiple myeloma. Studies often investigate mechanisms of immune cell function and interactions, with a particular focus on the behavior and regulation of blood components under various pathological conditions.

Best Publications

  • STAT3 REGULATES CYTOKINE-MEDIATED GENERATION OF INFLAMMATORY HELPER T CELLS

    Xuexian O. Yang;Athanasia D. Panopoulos;Roza Nurieva;Seon Hee Chang

  • Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

    Stephan Teglund;Catriona McKay;Erin Schuetz;Jan M van Deursen

  • Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors

    Evan Parganas;Demin Wang;Dimitrios Stravopodis;David J. Topham

  • Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

    Richard Moriggl;David J Topham;Stephan Teglund;Veronika Sexl

  • SOCS1 Deficiency Causes a Lymphocyte-Dependent Perinatal Lethality

    Jean Christophe Marine;David J. Topham;Catriona McKay;Demin Wang

  • Phospholipase Cγ2 Is Essential in the Functions of B Cell and Several Fc Receptors

    Demin Wang;Jian Feng;Jian Feng;Renren Wen;Jean-Christophe Marine

  • SOCS3 Is Essential in the Regulation of Fetal Liver Erythropoiesis

    Jean Christophe Marine;Catriona McKay;Demin Wang;David J. Topham

  • Essential, Nonredundant Role for the Phosphoinositide 3-Kinase p110δ in Signaling by the B-Cell Receptor Complex

    Shiann-Tarng Jou;Nick Carpino;Yutaka Takahashi;Roland Piekorz;Roland Piekorz

  • Phosphorylation of CARMA1 plays a critical role in T cell receptor-mediated NF-κB activation

    Reiko Matsumoto;Reiko Matsumoto;Donghai Wang;Marzenna Blonska;Hongxiu Li;Hongxiu Li

  • Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.

    Juerg Schwaller;Evan Parganas;Demin Wang;Danielle Cain

  • Naturally occurring dominant negative variants of Stat5

    D Wang;D Stravopodis;S Teglund;J Kitazawa

  • Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.

    F. W. Quelle;Demin Wang;T. Nosaka;W. E. Thierfelder

  • Stat5 tetramer formation is associated with leukemogenesis

    Richard Moriggl;Veronika Sexl;Lukas Kenner;Christopher Duntsch

  • STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and Function

    Roza I. Nurieva;Andrew Podd;Andrew Podd;Yuhong Chen;Andrei M. Alekseev

  • Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells.

    Liquan Xue;Stephan W Morris;Stephan W Morris;Carlos Orihuela;Elaine Tuomanen

  • Tyrosine kinase Btk regulates E-selectin–mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) γ2 and PI3Kγ pathways

    Helena Mueller;Helena Mueller;Anika Stadtmann;Anika Stadtmann;Hugo Van Aken;Emilio Hirsch

  • Immune checkpoint protein VISTA regulates antitumor immunity by controlling myeloid cell-mediated inflammation and immunosuppression

    Wenwen Xu;Juan Dong;Yongwei Zheng;Juan Zhou;Juan Zhou

  • IL-3 Induces Basophil Expansion In Vivo by Directing Granulocyte-Monocyte Progenitors to Differentiate into Basophil Lineage-Restricted Progenitors in the Bone Marrow and by Increasing the Number of Basophil/Mast Cell Progenitors in the Spleen

    Keitaro Ohmori;Yuchun Luo;Yi Jia;Jun Nishida

  • A small amphipathic α-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5

    Demin Wang;Richard Moriggl;Dimitrios Stravopodis;Nick Carpino

  • Antagonistic regulation by the transcription factors C/EBPα and MITF specifies basophil and mast cell fates.

    Xiaopeng Qi;Jessie Hong;Lee Chaves;Yonghua Zhuang

  • IDENTIFICATION OF SHP-2 AS A STAT5A PHOSPHATASE

    Yuhong Chen;Renren Wen;Shoua Yang;James Schuman

Frequent Co-Authors

James N. Ihle
James N. Ihle St. Jude Children's Research Hospital
Richard H. Aster
Richard H. Aster Medical College of Wisconsin
Debra K. Newman
Debra K. Newman Medical College of Wisconsin
Thomas F. DeLaney
Thomas F. DeLaney Harvard University
Jian Feng
Jian Feng University at Buffalo, State University of New York
Richard Moriggl
Richard Moriggl University of Veterinary Medicine Vienna
Brian R. Curtis
Brian R. Curtis University of Wisconsin–Milwaukee
John L. Cleveland
John L. Cleveland Moffitt Cancer Center
Stephan W. Morris
Stephan W. Morris St. Jude Children's Research Hospital

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