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Tomohiro Kurosaki

Tomohiro Kurosaki

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Biology and Biochemistry
Japan
2025

D-Index & Metrics

Immunology

D-Index
124
Citations
47143
World Ranking
302
National Ranking
13

Research.com Recognitions

  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Tomohiro Kurosaki is affiliated with Osaka University in Japan and has contributed extensively to research in immunology and microbiology, with a significant focus on immunology. Their work spans various subfields including infectious diseases, molecular biology, epidemiology, and oncology.

Kurosaki's recent research papers reflect a focus on T-cell and B-cell immunology, immune cell function, and immune responses. Notable publications include:

  • "Memory B cells," 2023, Nature reviews. Immunology
  • "BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells," 2021, Nature Immunology
  • "Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity," 2020, Nature Immunology
  • "BATF epigenetically and transcriptionally controls the activation program of regulatory T cells in human tumors," 2022, Science Immunology
  • "Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis," 2020, Nature Communications

Kurosaki has collaborated frequently with several co-authors including:

  • Takeshi Inoue
  • Wataru Ise
  • Ryo Shinnakasu
  • Yoshihiro Baba
  • Kohei Kometani

Their work has been published across a range of scientific journals. The most frequent publication venues include:

  • The Journal of Experimental Medicine
  • International Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Science Immunology

The main fields of study for Kurosaki involve immunology and microbiology and medicine. Specific subfields of interest are immunology, infectious diseases, molecular biology, epidemiology, and oncology. Their research topics prominently cover:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • interferon and immune responses
  • CAR-T cell therapy research

Best Publications

  • LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability

    Monica J. S. Nadler;Meredith C. Hermosura;Kazunori Inabe;Anne-Laure Perraud

  • PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

    Taku Okazaki;Akito Maeda;Hiroyuki Nishimura;Tomohiro Kurosaki

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling

    Tatsushi Muta;Tomohiro Kurosaki;Ziva Misulovin;Mercedes Sanchez

  • Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7.

    Carsten Schmitz;Anne-Laure Perraud;Catherine O Johnson;Kazunori Inabe

  • Memory B cells.

    Tomohiro Kurosaki;Kohei Kometani;Wataru Ise

  • Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways.

    M. Takata;H. Sabe;A. Hata;T. Inazu

  • Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis.

    Darren F. Boehning;Randen L. Patterson;Leela Sedaghat;Natalia O. Glebova

  • Zinc is a novel intracellular second messenger

    Satoru Yamasaki;Kumiko Sakata-Sogawa;Aiko Hasegawa;Tomoyuki Suzuki

  • Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling.

    Masao Ono;Hidetaka Okada;Silvia Bolland;Shigeru Yanagi

  • BLNK: a Central Linker Protein in B Cell Activation

    Chong Fu;Christoph W. Turck;Tomohiro Kurosaki;Andrew C. Chan

  • Molecular and Functional Characterization of a Novel Mouse Transient Receptor Potential Protein Homologue TRP7 Ca2+-PERMEABLE CATION CHANNEL THAT IS CONSTITUTIVELY ACTIVATED AND ENHANCED BY STIMULATION OF G PROTEIN-COUPLED RECEPTOR

    Takaharu Okada;Ryuji Inoue;Kazuto Yamazaki;Akito Maeda

  • Genetic analysis of B cell antigen receptor signaling.

    Tomohiro Kurosaki

  • A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

    M Takata;T Kurosaki

  • Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation

    Masanori Matsumoto;Akemi Baba;Takafumi Yokota;Hiroyoshi Nishikawa

  • SHIP Modulates Immune Receptor Responses by Regulating Membrane Association of Btk

    Silvia Bolland;Roger N Pearse;Roger N Pearse;Tomohiro Kurosaki;Jeffrey V Ravetch

  • Bcl6 Protein Expression Shapes Pre-Germinal Center B Cell Dynamics and Follicular Helper T Cell Heterogeneity

    Masahiro Kitano;Saya Moriyama;Yoshikazu Ando;Masaki Hikida

  • Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5‐trisphosphate receptors in signal transduction through the B‐cell antigen receptor

    Hitoshi Sugawara;Mari Kurosaki;Minoru Takata;Tomohiro Kurosaki

  • KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity.

    Dietmar Herndler-Brandstetter;Harumichi Ishigame;Ryo Shinnakasu;Valerie Plajer

  • BLNK Required for Coupling Syk to PLCγ2 and Rac1-JNK in B Cells

    Masamichi Ishiai;Mari Kurosaki;Rajita Pappu;Katsuya Okawa

  • Encoding of Ca2+ signals by differential expression of IP3 receptor subtypes

    Tomoya Miyakawa;Akito Maeda;Toshiko Yamazawa;Kenzo Hirose

Frequent Co-Authors

Yasuo Mori
Yasuo Mori Kyoto University
Shinya Tanaka
Shinya Tanaka Hokkaido University
Takashi Saito
Takashi Saito Nagoya City University
Masamichi Ishiai
Masamichi Ishiai Kyoto University
Masamitsu Iino
Masamitsu Iino Nihon University
Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Haruhiko Koseki
Haruhiko Koseki RIKEN Center for Integrative Medical Sciences
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Arthur Weiss
Arthur Weiss University of California, San Francisco
Osamu Ohara
Osamu Ohara Chiba University

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