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Osamu Ohara

Osamu Ohara

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Genetics

D-Index
103
Citations
44739
World Ranking
674
National Ranking
19

Molecular Biology

D-Index
103
Citations
44739
World Ranking
476
National Ranking
32

Medicine

D-Index
103
Citations
44547
World Ranking
7289
National Ranking
174

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Osamu Ohara is affiliated with Chiba University in Japan. Their research spans several main fields, including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these broad areas, their work focuses on subfields such as Immunology, Molecular Biology, Genetics, Epidemiology, and Hematology.

The principal topics explored by Ohara in their scientific output include:

  • Immune Cell Function and Interaction
  • Immunodeficiency and Autoimmune Disorders
  • Blood disorders and treatments
  • Inflammasome and immune disorders
  • Advanced Proteomics Techniques and Applications
  • IL-33, ST2, and ILC Pathways
  • T-cell and B-cell Immunology

Among recent publications by Ohara, several notable papers include:

  • Gut microbial carbohydrate metabolism contributes to insulin resistance, 2023, published in Nature
  • Acetate differentially regulates IgA reactivity to commensal bacteria, 2021, published in Nature
  • Single-Shot 10K Proteome Approach: Over 10,000 Protein Identifications by Data-Independent Acquisition-Based Single-Shot Proteomics with Ion Mobility Spectrometry, 2022, published in Journal of Proteome Research
  • Identification of trypsin-degrading commensals in the large intestine, 2022, published in Nature
  • Clinical characteristics and treatment of 50 cases of Blau syndrome in Japan confirmed by genetic analysis of the NOD2 mutation, 2020, published in Annals of the Rheumatic Diseases

Frequent co-authors collaborating with Ohara are:

  • Yusuke Kawashima
  • Ryo Konno
  • Daisuke Nakajima
  • Kohsuke Imai
  • Yoshinori Hasegawa

The venues where Ohara publishes regularly include:

  • Journal of Clinical Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Frontiers in Immunology
  • International Journal of Molecular Sciences

Best Publications

  • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

    Yukihiro Furusawa;Yuuki Obata;Shinji Fukuda;Takaho A. Endo

  • The Transcriptional Landscape of the Mammalian Genome

    P. Carninci;T. Kasukawa;S. Katayama;J. Gough

  • Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

    Fumihiko Ishikawa;Shuro Yoshida;Yoriko Saito;Atsushi Hijikata

  • Complete sequencing and characterization of 21,243 full-length human cDNAs

    Toshio Ota;Yutaka Suzuki;Tetsuo Nishikawa;Tetsuji Otsuki

  • Prediction of the Coding Sequences of Unidentified Human Genes. X. The Complete Sequences of 100 New cDNA Clones from Brain Which Can Code for Large Proteins in vitro

    Ken Ichi Ishikawa;Takahiro Nagase;Mikita Suyama;Nobuyuki Miyajima

  • Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome

    Takashi Ebisawa;Makoto Uchiyama;Naofumi Kajimura;Kazuo Mishima

  • A Mass Spectrometry-based Proteomic Approach for Identification of Serine/Threonine-phosphorylated Proteins by Enrichment with Phospho-specific Antibodies Identification of a Novel Protein, Frigg, as a Protein Kinase A Substrate

    Mads Grønborg;Troels Zakarias Kristiansen;Allan Stensballe;Jens S. Andersen

  • NetPath: a public resource of curated signal transduction pathways

    Kumaran Kandasamy;S. Sujatha Mohan;Rajesh Raju;Shivakumar Keerthikumar

  • Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells

    Yoriko Saito;Hiroshi Kitamura;Atsushi Hijikata;Mariko Tomizawa-Murasawa

  • Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

    Motoaki Wakiyama;Koji Takimoto;Osamu Ohara;Shigeyuki Yokoyama

  • IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9

    Katsuaki Hoshino;Takahiro Sugiyama;Mitsuru Matsumoto;Takashi Tanaka

  • One-sided polymerase chain reaction: the amplification of cDNA.

    Osamu Ohara;Robert L. Dorit;Walter Gilbert

  • Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

    Tadashi Imanishi;Takeshi Itoh;Yutaka Suzuki;Claire O'Donovan

  • Prediction of the Coding Sequences of Unidentified Human Genes. VI. The Coding Sequences of 80 New Genes (KIAA0201-KIAA0280) Deduced by Analysis of cDNA Clones from Cell Line KG-1 and Brain

    Takahiro Nagase;Naohiko Seki;Ken-ichi Ishikawa;Miki Ohira

  • Multitissue Circadian Expression of Rat periodHomolog (rPer2) mRNA Is Governed by the Mammalian Circadian Clock, the Suprachiasmatic Nucleus in the Brain

    Katsuhiko Sakamoto;Takahiro Nagase;Hiromi Fukui;Kazumasa Horikawa

  • High Incidence of NLRP3 Somatic Mosaicism in Patients With Chronic Infantile Neurologic, Cutaneous, Articular Syndrome: Results of an International Multicenter Collaborative Study

    Naoko Tanaka;Kazushi Izawa;Megumu K. Saito;Mio Sakuma

  • Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation

    Yasutaka Motomura;Hideaki Morita;Kazuyo Moro;Kazuyo Moro;Susumu Nakae

  • Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity

    Mitsuhiro Endoh;Takaho A. Endo;Tamie Endoh;Yu-ichi Fujimura

  • The Zinc Transporter SLC39A13/ZIP13 Is Required for Connective Tissue Development; Its Involvement in BMP/TGF-β Signaling Pathways

    Toshiyuki Fukada;Natacha Civic;Tatsuya Furuichi;Shinji Shimoda

  • Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene

    Osamu Ohara;Yoshinari Gahara;Toshihiko Miyake;Hiroshi Teraoka

Frequent Co-Authors

Takahiro Nagase
Takahiro Nagase Nara Institute of Science and Technology
Haruhiko Koseki
Haruhiko Koseki RIKEN Center for Integrative Medical Sciences
Kohsuke Imai
Kohsuke Imai Tokyo Medical and Dental University
Tomohiro Morio
Tomohiro Morio Institute of Science Tokyo
Shigeaki Nonoyama
Shigeaki Nonoyama National Defense Medical College
Toshio Heike
Toshio Heike Kyoto University
Hirokazu Kanegane
Hirokazu Kanegane Tokyo Medical and Dental University
Nobuo Nomura
Nobuo Nomura National Institute of Advanced Industrial Science and Technology
Leonard D. Shultz
Leonard D. Shultz Jackson Laboratory

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