World's Best Scientists 2026 revealed!
Toshio Heike

Toshio Heike

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
17189
World Ranking
10630
National Ranking
723

Toshio Heike publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Toshio Heike sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 323 publications — 82nd percentile

82% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Toshio Heike D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Toshio Heike sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 62 D-Index — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Toshio Heike is affiliated with Kyoto University in Japan and has made significant contributions to the field of medicine, focusing primarily on hematology and related subfields such as oncology, immunology, genetics, and pathology and forensic medicine. Their research output includes a substantial number of publications that span these scientific disciplines.

Their notable recent papers include:

  • Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria, 2024, New England Journal of Medicine
  • Treatment-free remission after first-line dasatinib discontinuation in patients with chronic myeloid leukaemia (first-line DADI trial): a single-arm, multicentre, phase 2 trial, 2020, The Lancet Haematology
  • Tracing the evolutionary history of blood cells to the unicellular ancestor of animals, 2022, Blood
  • EZH2 inhibitors restore epigenetically silenced CD58 expression in B-cell lymphomas, 2020, Molecular Immunology
  • Oncolytic Virus Therapy with HSV-1 for Hematological Malignancies, 2020, Molecular Therapy

Heike collaborates frequently with a number of researchers in their field. The most frequent co-authors include:

  • Akifumi Takaori-Kondo
  • Yasuyuki Arai
  • Junya Kanda
  • Kouhei Yamashita
  • Momoko Nishikori

Their work has been published extensively in several key scientific venues known for hematology and related research, including:

  • Scientific Reports
  • Transplantation and Cellular Therapy
  • Blood
  • International Journal of Hematology
  • British Journal of Haematology

Main research fields for Heike cover a broad spectrum of medicine, with a strong focus on hematology. Subfields represented in their publications include:

  • Hematology
  • Oncology
  • Immunology
  • Genetics
  • Pathology and Forensic Medicine

Their scientific investigation often centers on specific topics such as:

  • CAR-T cell therapy research
  • Hematopoietic Stem Cell Transplantation
  • Lymphoma Diagnosis and Treatment
  • Immune Cell Function and Interaction
  • Virus-based gene therapy research
  • Acute Myeloid Leukemia Research
  • Complement system in diseases

Best Publications

  • Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

    Makoto Miyara;Yumiko Yoshioka;Akihiko Kitoh;Tomoko Shima

  • NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells.

    Mamoru Ito;Hidefumi Hiramatsu;Kimio Kobayashi;Kazutomo Suzue

  • Generation of Pluripotent Stem Cells from Neonatal Mouse Testis

    Mito Kanatsu-Shinohara;Kimiko Inoue;Jiyoung Lee;Momoko Yoshimoto

  • Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-κB activation: common genetic etiology with Blau syndrome

    Nobuo Kanazawa;Ikuo Okafuji;Naotomo Kambe;Ryuta Nishikomori

  • Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/γcnull mice model

    Hidefumi Hiramatsu;Ryuta Nishikomori;Ryuta Nishikomori;Toshio Heike;Toshio Heike;Mamoru Ito;Mamoru Ito

  • High Incidence of NLRP3 Somatic Mosaicism in Patients With Chronic Infantile Neurologic, Cutaneous, Articular Syndrome: Results of an International Multicenter Collaborative Study

    Naoko Tanaka;Kazushi Izawa;Megumu K. Saito;Mio Sakuma

  • Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor κB (NF-κB) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes

    Rikimaru Bessho;Kousaku Matsubara;Masaru Kubota;Katsuji Kuwakado

  • Aicardi-Goutières syndrome is caused by IFIH1 mutations.

    Hirotsugu Oda;Kenji Nakagawa;Junya Abe;Tomonari Awaya

  • The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells.

    Noritaka Yokoo;Shiro Baba;Shinji Kaichi;Akira Niwa

  • Derivation of Mesenchymal Stromal Cells from Pluripotent Stem Cells through a Neural Crest Lineage using Small Molecule Compounds with Defined Media

    Makoto Fukuta;Yoshinori Nakai;Kosuke Kirino;Masato Nakagawa

  • Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreERT2

    Atsuko Yoshioka Higashi;Tomokatsu Ikawa;Masamichi Muramatsu;Aris N. Economides

  • Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes.

    Teruhisa Kawamura;Koh Ono;Tatsuya Morimoto;Hiromichi Wada

  • Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells

    Yuta Mizuno;Hsi Chang;Katsutsugu Umeda;Akira Niwa

  • Robust and Highly-Efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells under Serum- and Feeder Cell-Free Conditions

    Masakatsu D. Yanagimachi;Masakatsu D. Yanagimachi;Akira Niwa;Takayuki Tanaka;Fumiko Honda-Ozaki

  • Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis.

    Ikuo Okafuji;Ryuta Nishikomori;Nobuo Kanazawa;Naotomo Kambe

  • Ex vivo expansion of hematopoietic stem cells by cytokines

    Toshio Heike;Tatsutoshi Nakahata

  • Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients

    Megumu Saito;Ryuta Nishikomori;Naotomo Kambe;Naotomo Kambe;Akihiro Fujisawa

  • A Novel Serum-Free Monolayer Culture for Orderly Hematopoietic Differentiation of Human Pluripotent Cells via Mesodermal Progenitors

    Akira Niwa;Toshio Heike;Katsutsugu Umeda;Katsutsugu Umeda;Koichi Oshima

  • Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells.

    Akihiro Fujisawa;Naotomo Kambe;Megumu Saito;Ryuta Nishikomori

  • Human Umbilical Cord-Derived Mesenchymal Stromal Cells Differentiate Into Functional Schwann Cells That Sustain Peripheral Nerve Regeneration

    Dai Matsuse;Masaaki Kitada;Misaki Kohama;Kouki Nishikawa

Frequent Co-Authors

Tatsutoshi Nakahata
Tatsutoshi Nakahata Kyoto University
Souichi Adachi
Souichi Adachi Shiga Prefectural General Hospital
Osamu Ohara
Osamu Ohara Chiba University
Takeshi Morimoto
Takeshi Morimoto Kindai University
Shinya Yamanaka
Shinya Yamanaka Kyoto University
Hirofumi Suemori
Hirofumi Suemori Kyoto University
Yoshiki Miyachi
Yoshiki Miyachi Kyoto University
Norio Nakatsuji
Norio Nakatsuji Kyoto University
Akira Watanabe
Akira Watanabe Kyoto University
Seishi Ogawa
Seishi Ogawa Kyoto University

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