Toshio Heike

Overview

Best Publications

• Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

  Makoto Miyara;Yumiko Yoshioka;Akihiko Kitoh;Tomoko Shima

  2603
  Citations

• NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells.

  Mamoru Ito;Hidefumi Hiramatsu;Kimio Kobayashi;Kazutomo Suzue

  2143
  Citations

• Generation of Pluripotent Stem Cells from Neonatal Mouse Testis

  Mito Kanatsu-Shinohara;Kimiko Inoue;Jiyoung Lee;Momoko Yoshimoto

  1027
  Citations

• Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-κB activation: common genetic etiology with Blau syndrome

  Nobuo Kanazawa;Ikuo Okafuji;Naotomo Kambe;Ryuta Nishikomori

  534
  Citations

• Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/γcnull mice model

  Hidefumi Hiramatsu;Ryuta Nishikomori;Ryuta Nishikomori;Toshio Heike;Toshio Heike;Mamoru Ito;Mamoru Ito

  399
  Citations

• High Incidence of NLRP3 Somatic Mosaicism in Patients With Chronic Infantile Neurologic, Cutaneous, Articular Syndrome: Results of an International Multicenter Collaborative Study

  Naoko Tanaka;Kazushi Izawa;Megumu K. Saito;Mio Sakuma

  369
  Citations

• Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor κB (NF-κB) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes

  Rikimaru Bessho;Kousaku Matsubara;Masaru Kubota;Katsuji Kuwakado

  304
  Citations

• Aicardi-Goutières syndrome is caused by IFIH1 mutations.

  Hirotsugu Oda;Kenji Nakagawa;Junya Abe;Tomonari Awaya

  218
  Citations

• The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells.

  Noritaka Yokoo;Shiro Baba;Shinji Kaichi;Akira Niwa

  215
  Citations

• Derivation of Mesenchymal Stromal Cells from Pluripotent Stem Cells through a Neural Crest Lineage using Small Molecule Compounds with Defined Media

  Makoto Fukuta;Yoshinori Nakai;Kosuke Kirino;Masato Nakagawa

  213
  Citations

• Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreERT2

  Atsuko Yoshioka Higashi;Tomokatsu Ikawa;Masamichi Muramatsu;Aris N. Economides

  190
  Citations

• Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes.

  Teruhisa Kawamura;Koh Ono;Tatsuya Morimoto;Hiromichi Wada

  187
  Citations

• Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells

  Yuta Mizuno;Hsi Chang;Katsutsugu Umeda;Akira Niwa

  187
  Citations

• Robust and Highly-Efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells under Serum- and Feeder Cell-Free Conditions

  Masakatsu D. Yanagimachi;Masakatsu D. Yanagimachi;Akira Niwa;Takayuki Tanaka;Fumiko Honda-Ozaki

  181
  Citations

• Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis.

  Ikuo Okafuji;Ryuta Nishikomori;Nobuo Kanazawa;Naotomo Kambe

  173
  Citations

• Ex vivo expansion of hematopoietic stem cells by cytokines

  Toshio Heike;Tatsutoshi Nakahata

  166
  Citations

• Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients

  Megumu Saito;Ryuta Nishikomori;Naotomo Kambe;Naotomo Kambe;Akihiro Fujisawa

  163
  Citations

• A Novel Serum-Free Monolayer Culture for Orderly Hematopoietic Differentiation of Human Pluripotent Cells via Mesodermal Progenitors

  Akira Niwa;Toshio Heike;Katsutsugu Umeda;Katsutsugu Umeda;Koichi Oshima

  159
  Citations

• Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells.

  Akihiro Fujisawa;Naotomo Kambe;Megumu Saito;Ryuta Nishikomori

  157
  Citations

• Human Umbilical Cord-Derived Mesenchymal Stromal Cells Differentiate Into Functional Schwann Cells That Sustain Peripheral Nerve Regeneration

  Dai Matsuse;Masaaki Kitada;Misaki Kohama;Kouki Nishikawa

  151
  Citations