World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
101
Citations
41597
World Ranking
697
National Ranking
400

Medicine

D-Index
101
Citations
41586
World Ranking
7912
National Ranking
4118

Overview

Dale L. Greiner is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple disciplines including medicine, biochemistry, genetics, molecular biology, immunology, and microbiology, with a focus on several core subfields such as immunology, surgery, genetics, endocrinology, diabetes, metabolism, and molecular biology.

The main topics of their work center around pancreatic function and diabetes, diabetes and associated disorders, immune cell function and interaction, diabetes management and research, CAR-T cell therapy research, monoclonal and polyclonal antibodies research, and immunotherapy and immune responses.

Frequent co-authors collaborating with Dale L. Greiner include Leonard D. Shultz, Michael A. Brehm, James Keck, Greg Poffenberger, and Alvin C. Powers.

The scientist regularly publishes in several research venues, with notable frequency in the following journals:

  • Cancer Research
  • The FASEB Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Metabolism

Recent papers authored or co-authored by Dale L. Greiner include:

  • Humanized mouse models for immuno-oncology research, 2023, Nature Reviews Clinical Oncology
  • A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells, 2020, Nature Biomedical Engineering
  • Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy, 2020, Cell
  • Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells, 2020, Cell Reports
  • Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable, 2020, JCI Insight

Best Publications

  • Generation of functional human pancreatic β cells in vitro

    Felicia W. Pagliuca;Jeffrey R. Millman;Mads Gürtler;Michael Segel

  • Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.

    Leonard D. Shultz;Bonnie L. Lyons;Lisa M. Burzenski;Bruce Gott

  • Humanized mice in translational biomedical research

    Leonard D. Shultz;Fumihiko Ishikawa;Dale L. Greiner

  • Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.

    L D Shultz;P A Schweitzer;S W Christianson;B Gott

  • Humanized mice for immune system investigation: progress, promise and challenges.

    Leonard D. Shultz;Michael A. Brehm;J. Victor Garcia-Martinez;Dale L. Greiner

  • Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

    Omid Veiseh;Joshua C. Doloff;Minglin Ma;Arturo J. Vegas

  • Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

    Christine M. Oslowski;Takashi Hara;Takashi Hara;Takashi Hara;Bryan O'Sullivan-Murphy;Kohsuke Kanekura;Kohsuke Kanekura

  • Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice

    Arturo J Vegas;Arturo J Vegas;Arturo J Vegas;Omid Veiseh;Omid Veiseh;Mads Gürtler;Jeffrey R Millman

  • T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

    Priti Kumar;Hong Seok Ban;Sang Soo Kim;Haoquan Wu

  • Humanized Mouse Models of Clinical Disease.

    Nicole C. Walsh;Laurie L. Kenney;Sonal Jangalwe;Ken-Edwin Aryee

  • Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

    Arturo J Vegas;Arturo J Vegas;Arturo J Vegas;Omid Veiseh;Joshua C Doloff;Joshua C Doloff;Minglin Ma;Minglin Ma;Minglin Ma

  • SCID Mouse Models of Human Stem Cell Engraftment

    Dale L. Greiner;RuthAnn M. Hesselton;Leonard D. Shultz

  • Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand

    David C. Parker;Dale L. Greiner;Nancy E. Phillips;Michael C. Appel

  • Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.

    M A King;L Covassin;M A Brehm;W Racki

  • Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4

    Thomas G. Markees;Nancy E. Phillips;Ethel J. Gordon;Randolph J. Noelle

  • An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.

    Birgit Knoechel;Justine E Roderick;Kaylyn E Williamson;Jiang Zhu

  • Major Histocompatibility Complex Class I-Deficient NOD-B2mnull Mice are Diabetes and Insulitis Resistant

    David V Serreze;Edward H Leiter;Gregory J Christianson;Dale Greiner

  • Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

    Michael A. Brehm;Amy Cuthbert;Chaoxing Yang;David M. Miller

  • Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy

    Minan Wang;Li Chin Yao;Mingshan Cheng;Danying Cai

  • Humanized mouse models for immuno-oncology research

    Unknown

  • Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner.

    Neal N. Iwakoshi;John P. Mordes;Thomas G. Markees;Nancy E. Phillips

  • Human Lymphoid and Myeloid Cell Development in NOD/LtSz-scid IL2rγnull Mice Engrafted with Mobilized Human Hematopoietic Stem Cells.

    Leonard Shultz;Bonnie L. Lyons;Lisa M. Burzenski;Bruce Gott

Frequent Co-Authors

Leonard D. Shultz
Leonard D. Shultz Jackson Laboratory
John P. Mordes
John P. Mordes University of Massachusetts Chan Medical School
Aldo A. Rossini
Aldo A. Rossini University of Massachusetts Chan Medical School
Michael A. Brehm
Michael A. Brehm University of Massachusetts Chan Medical School
Randolph J. Noelle
Randolph J. Noelle Dartmouth College
Alvin C. Powers
Alvin C. Powers Vanderbilt University Medical Center
David C. Parker
David C. Parker Oregon Health & Science University
G.J. Igo
G.J. Igo University of California, Los Angeles

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