The scientist’s investigation covers issues in Immunology, NOD mice, Nod, Insulitis and T cell. David V. Serreze works mostly in the field of Immunology, limiting it down to concerns involving Cytotoxic T cell and, occasionally, Antigen. His NOD mice research is multidisciplinary, incorporating elements of Cytokine, T lymphocyte, Bone marrow and Locus.
His work in Bone marrow tackles topics such as Antigen presentation which are related to areas like Cell biology. His research integrates issues of Congenic, Internal medicine and MHC class I, Major histocompatibility complex in his study of Nod. The concepts of his Antigen-presenting cell study are interwoven with issues in Molecular biology and Lymphocyte.
His scientific interests lie mostly in Immunology, NOD mice, Nod, Major histocompatibility complex and T cell. His biological study spans a wide range of topics, including Diabetes mellitus, Type 1 diabetes and Cytotoxic T cell. His study in NOD mice is interdisciplinary in nature, drawing from both Congenic and MHC class I, CD8, Antigen.
In Nod, he works on issues like Islet, which are connected to Transplantation. The Major histocompatibility complex study combines topics in areas such as Haematopoiesis, Human leukocyte antigen and Antigen presentation. His T cell study combines topics in areas such as Beta cell, Lymphocyte, Cell biology, Bone marrow and FOXP3.
David V. Serreze mainly focuses on NOD mice, Immunology, Nod, T cell and Cytotoxic T cell. He combines subjects such as Phenotype, Major histocompatibility complex, Insulitis and Cell biology with his study of NOD mice. His studies in Immunology integrate themes in fields like Type 1 diabetes and Pancreatic islets.
His research in Nod intersects with topics in Peripherin, Lacrimal gland and CD8, Antigen. His T cell study integrates concerns from other disciplines, such as Myeloid and Regulatory B cells. In his research, Metabolism and Antibiotics is intimately related to Immune system, which falls under the overarching field of Cytotoxic T cell.
His main research concerns Immunology, NOD mice, Nod, T cell and Genetics. His works in Antibody and Naive B cell are all subjects of inquiry into Immunology. The various areas that he examines in his NOD mice study include Insulitis, Atacicept, Epitope, Cell biology and Peripherin.
His Nod research incorporates elements of Adoptive cell transfer and CD8, Antigen. His study in the fields of Major histocompatibility complex, Negative selection, Immune system and Inbred strain under the domain of Genetics overlaps with other disciplines such as Genetic divergence. David V. Serreze interconnects Cytotoxic T cell and Autoimmunity in the investigation of issues within Major histocompatibility complex.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.
D V Serreze;H D Chapman;D S Varnum;M S Hanson.
Journal of Experimental Medicine (1996)
Single domain antibodies: promising experimental and therapeutic tools in infection and immunity.
Janusz Wesolowski;Vanina Alzogaray;Jan Reyelt;Mandy Unger.
Medical Microbiology and Immunology (2009)
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.
M J Rapoport;A Jaramillo;D Zipris;A H Lazarus.
Journal of Experimental Medicine (1993)
B Lymphocytes Are Critical Antigen-Presenting Cells for the Initiation of T Cell-Mediated Autoimmune Diabetes in Nonobese Diabetic Mice
David V. Serreze;Sara A. Fleming;Harold D. Chapman;Scott D. Richard.
Journal of Immunology (1998)
Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice
Rulang Jiang;Yu Lan;Harry D. Chapman;Carrie Shawber.
Genes & Development (1998)
Identification of the β cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes
Scott M. Lieberman;Anne M. Evans;Bingye Han;Toshiyuki Takaki.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity
Jun Yamanouchi;Dan Rainbow;Pau Serra;Sarah Howlett.
Nature Genetics (2007)
Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice.
Michal Prochazka;Edward H. Leiter;David V. Serreze;Douglas L. Coleman.
TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes.
Rozita Razavi;Yin Chan;F. Nikoo Afifiyan;Xue Jun Liu.
Major Histocompatibility Complex Class I-Deficient NOD-B2mnull Mice are Diabetes and Insulitis Resistant
David V Serreze;Edward H Leiter;Gregory J Christianson;Dale Greiner.
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: