World's Best Scientists 2026 revealed!
Jean-François Bach

Jean-François Bach

D-Index & Metrics

Immunology

D-Index
96
Citations
38234
World Ranking
848
National Ranking
27

Medicine

D-Index
96
Citations
38439
World Ranking
9568
National Ranking
291

Overview

Jean-François Bach was affiliated with Grenoble Alpes University in France. Their research spanned several interconnected fields, primarily focusing on Medicine and Biochemistry, Genetics and Molecular Biology. Within these domains, their work covered subfields such as Molecular Biology, Surgery, Genetics, Infectious Diseases, and Immunology.

The scientific contributions of Jean-François Bach addressed several key topics, including:

  • Pancreatic function and diabetes
  • Protein Tyrosine Phosphatases
  • Diabetes and associated disorders
  • IL-33, ST2, and ILC Pathways
  • Asthma and respiratory diseases
  • Pediatric health and respiratory diseases
  • SARS-CoV-2 and COVID-19 Research

Their recent published papers include:

  • "Revisiting the Hygiene Hypothesis in the Context of Autoimmunity," 2021, Frontiers in Immunology
  • "De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes," 2021, Proceedings of the National Academy of Sciences
  • "COVID-19: individual and herd immunity," 2021, Comptes Rendus Biologies
  • "Modulation of autoimmune diabetes by N-ethyl-N-nitrosourea-induced mutations in non-obese diabetic mice," 2022, Disease Models & Mechanisms
  • "André Capron 1930-2020," 2020, Comptes Rendus Biologies

Jean-François Bach frequently published in the following venues:

  • Comptes Rendus Biologies
  • Frontiers in Immunology
  • Proceedings of the National Academy of Sciences
  • Disease Models & Mechanisms
  • Clinical Medicine Research

Their collaborations included several frequently co-authored researchers such as Lucienne Chatenoud, Sara Hildebrand, Cindy Marquet, Fabrice Valette, and Lindsay Scott. These collaborations contributed to multiple publications, indicating ongoing scientific partnerships.

Best Publications

  • The Effect of Infections on Susceptibility to Autoimmune and Allergic Diseases

    Jean-Francois Bach

  • The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

    H. Okada;C. Kuhn;H. Feillet;J.-F. Bach

  • Insulin-Dependent Diabetes Mellitus as an Autoimmune Disease

    Jean-François Bach

  • Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

    Lucienne Chatenoud;Eric Thervet;Jacqueline Primo;Jean-Francois Bach

  • TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes.

    Mériam Belghith;Jeffrey A Bluestone;Samia Barriot;Jérôme Mégret

  • Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients

    Anne Joutel;Katayoun Vahedi;Christophe Corpechot;Alain Troesch

  • Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

    A Bendelac;C Carnaud;C Boitard;J F Bach

  • Activation of natural killer T cells by α -galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

    Shayan Sharif;Guillermo A. Arreaza;Peter Zucker;Qing-Sheng Mi

  • CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice.

    L Chatenoud;J Primo;J F Bach

  • The hygiene hypothesis in autoimmunity: the role of pathogens and commensals

    Jean-François Bach;Jean-François Bach

  • Early quantitative and functional deficiency of NK1+‐like thymocytes in the NOD mouse

    Jean-Marc Gombert;André Herbelin;Emmanuelle Tancrède-Bohin;Michel Dy

  • Overexpression of Natural Killer T Cells Protects Vα14-Jα281 Transgenic Nonobese Diabetic Mice against Diabetes

    Agnès Lehuen;Olivier Lantz;Lucie Beaudoin;Véronique Laloux

  • Infections and autoimmune diseases.

    Jean-François Bach

  • Recurrent Mutations in a Single Exon Encoding the Evolutionarily Conserved Olfactomedin-Homology Domain of TIGR in Familial Open-Angle Glaucoma

    Marie F. Adam;Ahmed Belmouden;Philippe Binisti;Antoine P. Brézin

  • Factors associated with early remission of type I diabetes in children treated with cyclosporine.

    P.F. Bougneres;J.C. Carel;L. Castano;C. Boitard

  • Contribution of zinc and other metals to the biological activity of the serum thymic factor

    Mireille Dardenne;Jean-Marie Pleau;Bernadette Nabarra;Pierre Lefrancier

  • In vivo cell activation following OKT3 administration. Systemic cytokine release and modulation by corticosteroids.

    Lucienne Chatenoud;Christiane Ferran;Christophe Legendre;Isabelle Thouard

  • Prevention of diabetes in NOD mice treated with antibody to murine IFNγ

    Monique Debray-Sachs;Claude Carnaud;Christian Boitard;Hélène Cohen

  • Association of anti-β2 glycoprotein I antibodies with lupus-type circulating anticoagulant and thrombosis in systemic lupus erythematosus☆

    Jean-Paul Viard;Zahir Amoura;Jean-François Bach

  • Isolation, biochemical characteristics, and biological activity of a circulating thymic hormone in the mouse and in the human.

    Jean-François Bach;Mireille Dardenne;Jean-Marie Pleau;Marie-Anne Bach

Frequent Co-Authors

Mireille Dardenne
Mireille Dardenne Centre national de la recherche scientifique, CNRS
Christian Boitard
Christian Boitard Université Paris Cité
Henri Kreis
Henri Kreis Necker-Enfants Malades Hospital
Bruno Eymard
Bruno Eymard Université Paris Cité
François Tron
François Tron University of Rouen
Jean-Paul Viard
Jean-Paul Viard Assistance Publique – Hôpitaux de Paris
Elisabeth Tournier-Lasserve
Elisabeth Tournier-Lasserve Université Paris Cité

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Best Scientists Citing Jean-François Bach