D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 80 Citations 20,037 266 World Ranking 659 National Ranking 19
Medicine D-index 87 Citations 22,783 326 World Ranking 6926 National Ranking 217

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Internal medicine

His main research concerns Immunology, Type 1 diabetes, Autoimmunity, Islet and Antigen. His study focuses on the intersection of Immunology and fields such as Transplantation with connections in the field of Mannan-binding lectin. Diabetes mellitus covers Bart O. Roep research in Type 1 diabetes.

His work deals with themes such as Internal medicine, Insulin and Pathogenesis, which intersect with Diabetes mellitus. His work carried out in the field of Autoimmunity brings together such families of science as Cytotoxic T cell, Beta cell and Immunotherapy. His Antigen study combines topics in areas such as T cell, Autoantibody and Proinsulin.

His most cited work include:

  • Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes (683 citations)
  • Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients (454 citations)
  • Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients (432 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Immunology, Type 1 diabetes, Autoimmunity, Islet and Immune system. In most of his Immunology studies, his work intersects topics such as Transplantation. His Type 1 diabetes research integrates issues from Internal medicine, Insulin and Disease.

His studies in Internal medicine integrate themes in fields like Gastroenterology and Oncology. Bart O. Roep has researched Autoimmunity in several fields, including Autoantibody, Beta cell, Pancreas and Immunotherapy. The Epitope study which covers Human leukocyte antigen that intersects with Allele and Genotype.

He most often published in these fields:

  • Immunology (74.15%)
  • Type 1 diabetes (58.05%)
  • Autoimmunity (35.61%)

What were the highlights of his more recent work (between 2018-2021)?

  • Type 1 diabetes (58.05%)
  • Diabetes mellitus (27.32%)
  • Immune system (32.68%)

In recent papers he was focusing on the following fields of study:

Bart O. Roep mainly investigates Type 1 diabetes, Diabetes mellitus, Immune system, Islet and Immunology. His Type 1 diabetes research includes themes of Bioinformatics, Intensive treatment, C-peptide and Autoimmunity, Disease. In his study, Disease progression is strongly linked to T cell, which falls under the umbrella field of Autoimmunity.

His research in Immune system intersects with topics in Antigen and Cell biology. His Islet research is multidisciplinary, incorporating elements of Transplantation and Genotype. Bart O. Roep connects Immunology with Context in his research.

Between 2018 and 2021, his most popular works were:

  • Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. (89 citations)
  • Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. (89 citations)
  • Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes (51 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Internal medicine

Bart O. Roep mostly deals with Type 1 diabetes, Diabetes mellitus, Immune system, Disease and Autoimmunity. Type 1 diabetes is often connected to Bioinformatics in his work. Bart O. Roep focuses mostly in the field of Diabetes mellitus, narrowing it down to topics relating to Internal medicine and, in certain cases, Cell Plasticity and Cellular differentiation.

His studies deal with areas such as Carbohydrate metabolism, Antigen and Cell biology as well as Immune system. His work in Disease addresses issues such as Precision medicine, which are connected to fields such as Endotype, Genetic predisposition, Translational research and Islet. As a member of one scientific family, Bart O. Roep mostly works in the field of Immunotherapy, focusing on Peptide and, on occasion, Autoimmune disease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes

Shelley Lindley;Colin M. Dayan;Amanda Bishop;Bart O. Roep.
Diabetes (2005)

951 Citations

Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

Francesco Dotta;Stefano Censini;Astrid G. S. van Halteren;Lorella Marselli.
Proceedings of the National Academy of Sciences of the United States of America (2007)

559 Citations

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

Sefina Arif;Timothy I. Tree;Thomas P. Astill;Jennifer M. Tremble.
Journal of Clinical Investigation (2004)

500 Citations

The role of T-cells in the pathogenesis of Type 1 diabetes: from cause to cure.

Bart O. Roep.
Diabetologia (2003)

382 Citations

CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

Ania Skowera;Richard J. Ellis;Ruben Varela-Calviño;Sefina Arif.
Journal of Clinical Investigation (2008)

360 Citations

Development of type 1 diabetes despite severe hereditary B-cell deficiency.

Stephan Martin;Dorothea Wolf-Eichbaum;Gaby Duinkerken;Werner A. Scherbaum.
The New England Journal of Medicine (2001)

334 Citations

Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes

Gabrielle G. M. Pinkse;Odette H. M. Tysma;Cees A. M. Bergen;Michel G. D. Kester.
Proceedings of the National Academy of Sciences of the United States of America (2005)

320 Citations

Induction of Treg by monocyte‐derived DC modulated by vitamin D3 or dexamethasone: Differential role for PD‐L1

Wendy W. J. Unger;Sandra Laban;Fleur S. Kleijwegt;Arno R. van der Slik.
European Journal of Immunology (2009)

314 Citations

KIR in Type 1 Diabetes: Disparate Distribution of Activating and Inhibitory Natural Killer Cell Receptors in Patients Versus HLA-Matched Control Subjects

Arno R. van der Slik;Bobby P.C. Koeleman;Willem Verduijn;G. Jan Bruining.
Diabetes (2003)

275 Citations

Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.

T. P. Di Lorenzo;M. Peakman;B. O. Roep.
Clinical and Experimental Immunology (2007)

261 Citations

Best Scientists Citing Bart O. Roep

Mark Peakman

Mark Peakman

King's College London

Publications: 120

Matthias von Herrath

Matthias von Herrath

La Jolla Institute For Allergy & Immunology

Publications: 96

Chantal Mathieu

Chantal Mathieu

KU Leuven

Publications: 93

Mikael Knip

Mikael Knip

University of Helsinki

Publications: 77

Jorma Ilonen

Jorma Ilonen

University of Turku

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Mark A. Atkinson

Mark A. Atkinson

University of Florida

Publications: 69

George S. Eisenbarth

George S. Eisenbarth

University of Colorado Denver

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Carla J. Greenbaum

Carla J. Greenbaum

Virginia Mason Medical Center

Publications: 58

Åke Lernmark

Åke Lernmark

Lund University

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Ezio Bonifacio

Ezio Bonifacio

TU Dresden

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Kevan C. Herold

Kevan C. Herold

Yale University

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Gerald T. Nepom

Gerald T. Nepom

Virginia Mason Medical Center

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Jamie Rossjohn

Jamie Rossjohn

Monash University

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Heikki Hyöty

Heikki Hyöty

Tampere University

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Johnny Ludvigsson

Johnny Ludvigsson

Linköping University

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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