D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 85 Citations 21,640 326 World Ranking 830 National Ranking 25
Medicine D-index 88 Citations 22,697 360 World Ranking 8535 National Ranking 303

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Internal medicine

His main research concerns Immunology, Type 1 diabetes, Autoimmunity, Islet and Antigen. His study focuses on the intersection of Immunology and fields such as Transplantation with connections in the field of Mannan-binding lectin. Diabetes mellitus covers Bart O. Roep research in Type 1 diabetes.

His work deals with themes such as Internal medicine, Insulin and Pathogenesis, which intersect with Diabetes mellitus. His work carried out in the field of Autoimmunity brings together such families of science as Cytotoxic T cell, Beta cell and Immunotherapy. His Antigen study combines topics in areas such as T cell, Autoantibody and Proinsulin.

His most cited work include:

  • Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes (683 citations)
  • Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients (454 citations)
  • Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients (432 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Immunology, Type 1 diabetes, Autoimmunity, Islet and Immune system. In most of his Immunology studies, his work intersects topics such as Transplantation. His Type 1 diabetes research integrates issues from Internal medicine, Insulin and Disease.

His studies in Internal medicine integrate themes in fields like Gastroenterology and Oncology. Bart O. Roep has researched Autoimmunity in several fields, including Autoantibody, Beta cell, Pancreas and Immunotherapy. The Epitope study which covers Human leukocyte antigen that intersects with Allele and Genotype.

He most often published in these fields:

  • Immunology (74.15%)
  • Type 1 diabetes (58.05%)
  • Autoimmunity (35.61%)

What were the highlights of his more recent work (between 2018-2021)?

  • Type 1 diabetes (58.05%)
  • Diabetes mellitus (27.32%)
  • Immune system (32.68%)

In recent papers he was focusing on the following fields of study:

Bart O. Roep mainly investigates Type 1 diabetes, Diabetes mellitus, Immune system, Islet and Immunology. His Type 1 diabetes research includes themes of Bioinformatics, Intensive treatment, C-peptide and Autoimmunity, Disease. In his study, Disease progression is strongly linked to T cell, which falls under the umbrella field of Autoimmunity.

His research in Immune system intersects with topics in Antigen and Cell biology. His Islet research is multidisciplinary, incorporating elements of Transplantation and Genotype. Bart O. Roep connects Immunology with Context in his research.

Between 2018 and 2021, his most popular works were:

  • Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. (89 citations)
  • Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. (89 citations)
  • Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes (51 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Internal medicine

Bart O. Roep mostly deals with Type 1 diabetes, Diabetes mellitus, Immune system, Disease and Autoimmunity. Type 1 diabetes is often connected to Bioinformatics in his work. Bart O. Roep focuses mostly in the field of Diabetes mellitus, narrowing it down to topics relating to Internal medicine and, in certain cases, Cell Plasticity and Cellular differentiation.

His studies deal with areas such as Carbohydrate metabolism, Antigen and Cell biology as well as Immune system. His work in Disease addresses issues such as Precision medicine, which are connected to fields such as Endotype, Genetic predisposition, Translational research and Islet. As a member of one scientific family, Bart O. Roep mostly works in the field of Immunotherapy, focusing on Peptide and, on occasion, Autoimmune disease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes

Shelley Lindley;Colin M. Dayan;Amanda Bishop;Bart O. Roep.
Diabetes (2005)

1059 Citations

Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

Francesco Dotta;Stefano Censini;Astrid G. S. van Halteren;Lorella Marselli.
Proceedings of the National Academy of Sciences of the United States of America (2007)

639 Citations

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

Ken T. Coppieters;Francesco Dotta;Natalie Amirian;Peter D. Campbell.
Journal of Experimental Medicine (2012)

611 Citations

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

Sefina Arif;Timothy I. Tree;Thomas P. Astill;Jennifer M. Tremble.
Journal of Clinical Investigation (2004)

559 Citations

The role of T-cells in the pathogenesis of Type 1 diabetes: From cause to cure

Bart O. Roep.
Diabetologia (2003)

511 Citations

Induction of Treg by monocyte‐derived DC modulated by vitamin D3 or dexamethasone: Differential role for PD‐L1

Wendy W. J. Unger;Sandra Laban;Fleur S. Kleijwegt;Arno R. van der Slik.
European Journal of Immunology (2009)

450 Citations

CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

Ania Skowera;Richard J. Ellis;Ruben Varela-Calviño;Sefina Arif.
Journal of Clinical Investigation (2008)

407 Citations

Development of type 1 diabetes despite severe hereditary B-cell deficiency.

Stephan Martin;Dorothea Wolf-Eichbaum;Gaby Duinkerken;Werner A. Scherbaum.
The New England Journal of Medicine (2001)

348 Citations

Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes

Gabrielle G. M. Pinkse;Odette H. M. Tysma;Cees A. M. Bergen;Michel G. D. Kester.
Proceedings of the National Academy of Sciences of the United States of America (2005)

321 Citations

KIR in Type 1 Diabetes: Disparate Distribution of Activating and Inhibitory Natural Killer Cell Receptors in Patients Versus HLA-Matched Control Subjects

Arno R. van der Slik;Bobby P.C. Koeleman;Willem Verduijn;G. Jan Bruining.
Diabetes (2003)

290 Citations

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