His primary scientific interests are in Immunology, Epitope, Antigen, Cytotoxic T cell and Immune system. The various areas that Jan W. Drijfhout examines in his Epitope study include Molecular biology, Peptide, Human leukocyte antigen, CTL* and Gliadin. His Peptide study is focused on Biochemistry in general.
His work carried out in the field of Antigen brings together such families of science as T cell and Islet. His Cytotoxic T cell research is multidisciplinary, incorporating perspectives in Immunotherapy, CD8, Minor histocompatibility antigen and Virology. His work in Immune system tackles topics such as Cervical cancer which are related to areas like Prognostic variable, Tumor-infiltrating lymphocytes, Pathology and Lymph node.
Jan W. Drijfhout mainly investigates Immunology, Epitope, Peptide, Antigen and Biochemistry. Immunology is represented through his Immune system, T cell, Antibody, CD8 and Rheumatoid arthritis research. His studies deal with areas such as T lymphocyte and Molecular mimicry as well as T cell.
While the research belongs to areas of Epitope, Jan W. Drijfhout spends his time largely on the problem of Human leukocyte antigen, intersecting his research to questions surrounding Minor histocompatibility antigen. His research integrates issues of Peptide sequence, Computational biology, Peptide binding and Microbiology in his study of Peptide. Jan W. Drijfhout has researched Antigen in several fields, including Antigen presentation and Cell biology.
His primary areas of study are Microbiology, Peptide, Immune system, Immunology and Epitope. His biological study spans a wide range of topics, including Isopeptidase activity, Hydroxylamine, Tissue transglutaminase, Gene silencing and Gliadin. In the subject of general Immunology, his work in Antibody, T cell and T cell reactivity is often linked to Narcolepsy, thereby combining diverse domains of study.
He has included themes like Rheumatoid arthritis and Antigen in his Antibody study. His T cell research incorporates elements of Cytotoxic T cell, MHC class I, CD8 and B cell. He combines subjects such as Vaccination, Virology, Preproinsulin, Molecular biology and Human leukocyte antigen with his study of Epitope.
Jan W. Drijfhout focuses on Microbiology, Antimicrobial peptides, Antimicrobial, Peptide and Biochemistry. His Microbiology research includes themes of Pichia pastoris and Biofilm. His Antimicrobial peptides research incorporates themes from Cell wall, Antibiotics, Antibiotic resistance and Membrane protein.
The concepts of his Antimicrobial study are interwoven with issues in Methicillin-resistant Staphylococcus aureus and Staphylococcus aureus. His work often combines Peptide and Diagnostic test studies. While working in this field, Jan W. Drijfhout studies both Biochemistry and Context.
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Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia
Gemma G Kenter;Marij J P Welters;A Rob P M Valentijn;Margriet J G Lowik.
The New England Journal of Medicine (2009)
Vaccination with cytotoxic T lymphocyte epitope‐containing peptide protects against a tumor induced by human papillomavirus type 16‐transformed cells
M. C. W. Feltkamp;H. L. Smits;M. P. M. Vierboom;R. P. Minnaar.
European Journal of Immunology (1993)
The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides
Willemijn Vader;Yvonne Kooy;Peter van Veelen;Arnoud de Ru.
The Antimicrobial Peptide LL-37 Activates Innate Immunity at the Airway Epithelial Surface by Transactivation of the Epidermal Growth Factor Receptor
G. Sandra Tjabringa;Jamil Aarbiou;Dennis K. Ninaber;Jan Wouter Drijfhout.
Journal of Immunology (2003)
Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia.
W. A. Erik Marijt;Mirjam H. M. Heemskerk;Freke M. Kloosterboer;Els Goulmy.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Cross-presentation by intercellular peptide transfer through gap junctions
Joost Neijssen;Carla Herberts;Jan Wouter Drijfhout;Eric Reits.
Specificity of Tissue Transglutaminase Explains Cereal Toxicity in Celiac Disease
L. Willemijn Vader;Arnoud de Ru;Yvonne van der Wal;Yvonne M.C. Kooy.
Journal of Experimental Medicine (2002)
Identification of a Graft-versus-Host Disease-associated human minor Histocompatibility antigen.
Joke M. M. den Haan;Nicholas E. Sherman;Els Blokland;Eric Huczko.
Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine.
Marij J P Welters;Gemma G Kenter;Sytse J Piersma;Annelies P G Vloon.
Clinical Cancer Research (2008)
High Number of Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes Is Associated with the Absence of Lymph Node Metastases in Patients with Large Early-Stage Cervical Cancer
Sytse J. Piersma;Ekaterina S. Jordanova;Mariëtte I.E. van Poelgeest;Kitty M.C. Kwappenberg.
Cancer Research (2007)
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