World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
100
Citations
33320
World Ranking
732
National Ranking
27

Medicine

D-Index
100
Citations
33320
World Ranking
8330
National Ranking
326

Overview

Sjoerd H. van der Burg is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on medicine, with substantial contributions to immunology and microbiology. Within these broader fields, the scientist has explored oncology, immunology, epidemiology, molecular biology, and genetics.

Their work addresses several main topics: immunotherapy and immune responses, cancer immunotherapy and biomarkers, CAR-T cell therapy research, cervical cancer and HPV research, immune cell function and interaction, immune cells in cancer, and pancreatic and hepatic oncology research.

Recent notable publications include:

  • Therapeutic cancer vaccines, 2021, Nature Reviews. Cancer
  • The NKG2A-HLA-E Axis as a Novel Checkpoint in the Tumor Microenvironment, 2020, Clinical Cancer Research
  • CD39 Identifies the CD4+ Tumor-Specific T-cell Population in Human Cancer, 2020, Cancer Immunology Research
  • Vulvar cancer subclassification by HPV and p53 status results in three clinically distinct subtypes, 2020, Gynecologic Oncology
  • Strong vaccine responses during chemotherapy are associated with prolonged cancer survival, 2020, Science Translational Medicine

Their frequent co-authors include:

  • Marij J.P. Welters
  • Thorbald van Hall
  • Els M.E. Verdegaal
  • Saskia J. Santegoets
  • Noel F.C.C. de Miranda

Most of their research has been published in the following venues:

  • Journal for ImmunoTherapy of Cancer
  • Journal of Clinical Oncology
  • Clinical Cancer Research
  • Cancer Immunology Research
  • Cancer Immunology Immunotherapy

Best Publications

  • Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

    Gemma G Kenter;Marij J P Welters;A Rob P M Valentijn;Margriet J G Lowik

  • Therapeutic cancer vaccines

    Cornelis J.M. Melief;Thorbald van Hall;Ramon Arens;Ferry Ossendorp

  • Actively personalized vaccination trial for newly diagnosed glioblastoma

    Norbert Hilf;Sabrina Kuttruff-Coqui;Katrin Frenzel;Valesca Bukur

  • Vaccines for established cancer: overcoming the challenges posed by immune evasion.

    Sjoerd H. van der Burg;Ramon Arens;Ferry Ossendorp;Thorbald van Hall

  • High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4 + T cells in human melanoma

    Carsten Linnemann;Marit M van Buuren;Laura Bies;Els M E Verdegaal

  • Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines

    Cornelis J.M. Melief;Sjoerd H. van der Burg

  • Comprehensive control of human papillomavirus infections and related diseases.

    F. Xavier Bosch;Thomas R. Broker;David Forman;Anna Barbara Moscicki

  • A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence

    Joanna Kaplon;Liang Zheng;Katrin Meissl;Barbara Chaneton

  • Established Human Papillomavirus Type 16-Expressing Tumors Are Effectively Eradicated Following Vaccination with Long Peptides

    Sander Zwaveling;Sandra C. Ferreira Mota;Jan Nouta;Mark Johnson

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Identification and manipulation of tumor associated macrophages in human cancers

    Moniek Heusinkveld;Sjoerd H van der Burg

  • High Number of Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes Is Associated with the Absence of Lymph Node Metastases in Patients with Large Early-Stage Cervical Cancer

    Sytse J. Piersma;Ekaterina S. Jordanova;Mariëtte I.E. van Poelgeest;Kitty M.C. Kwappenberg

  • Neoantigen landscape dynamics during human melanoma–T cell interactions

    Els M. E. Verdegaal;Noel F. C. C. de Miranda;Marten Visser;Tom Harryvan

  • Induction of tumor-specific CD4+ and CD8+ T-cell immunity in cervical cancer patients by a human papillomavirus type 16 E6 and E7 long peptides vaccine.

    Marij J P Welters;Gemma G Kenter;Sytse J Piersma;Annelies P G Vloon

  • Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial.

    Erminia Massarelli;William William;Faye Johnson;Merrill Kies

  • Phase I immunotherapeutic trial with long peptides spanning the E6 and E7 sequences of high-risk human papillomavirus 16 in end-stage cervical cancer patients shows low toxicity and robust immunogenicity

    Gemma G Kenter;Marij J P Welters;A Rob P M Valentijn;Margriet J G Lowik

  • Anti-CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response.

    Pia Kvistborg;Daisy Philips;Sander Kelderman;Lois Hageman

  • Human Papillomavirus Type 16-Positive Cervical Cancer Is Associated with Impaired CD4+ T-Cell Immunity against Early Antigens E2 and E6

    Annemieke de Jong;Mariëtte I. E. van Poelgeest;Jeanette M. van der Hulst;Jan Wouter Drijfhout

  • Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment

    Eveline M. Dijkgraaf;Moniek Heusinkveld;Bart Tummers;Lisa T.C. Vogelpoel

  • M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells.

    Moniek Heusinkveld;Peggy J. de Vos van Steenwijk;Renske Goedemans;Tamara H. Ramwadhdoebe

  • High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4(+) T cells in human melanoma (vol 21, pg 81, 2015)

    Carsten Linnemann;Marit M. van Buuren;Laura Bies;Els M. E. Verdegaal

Frequent Co-Authors

Cornelis J. M. Melief
Cornelis J. M. Melief ISA Pharmaceuticals (Netherlands)
Marij J. P. Welters
Marij J. P. Welters Leiden University Medical Center
Rienk Offringa
Rienk Offringa German Cancer Research Center
Thorbald van Hall
Thorbald van Hall Leiden University Medical Center
Gemma G. Kenter
Gemma G. Kenter Vrije Universiteit Amsterdam
Jan W. Drijfhout
Jan W. Drijfhout Leiden University Medical Center
Gert Jan Fleuren
Gert Jan Fleuren Leiden University Medical Center
Ferry Ossendorp
Ferry Ossendorp Leiden University Medical Center
Kees L. M. C. Franken
Kees L. M. C. Franken Leiden University Medical Center
Hans W. Nijman
Hans W. Nijman University Medical Center Groningen

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