World's Best Scientists 2026 revealed!

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Immunology

D-Index
78
Citations
20935
World Ranking
1759
National Ranking
67

Medicine

D-Index
78
Citations
21096
World Ranking
18086
National Ranking
602

Research.com Recognitions

  • 2018 - Fellow of the Royal Society of Edinburgh
  • 2014 - Fellow of the Australian Academy of Health and Medical Science
  • 2011 - Fellow of the Royal Society, United Kingdom
  • 2008 - Prime Minister's Prize for Science, Australia For his creation of the first vaccine designed to protect against a cancer
  • 2008 - International Balzan Prize
  • 2006 - Florey Medal, Australian Institute of Policy & Science for development of the cervical cancer vaccine Gardasil
  • 2004 - Fellow of the Australian Academy of Science

Overview

Ian H. Frazer is affiliated with the University of Queensland in Australia. Their research spans multiple areas within Medicine and Immunology and Microbiology, with a detailed focus on Immunology, Epidemiology, Oncology, Molecular Biology, and Otorhinolaryngology.

The scientist has contributed extensively to topics such as Immunotherapy and Immune Responses, Cervical Cancer and HPV Research, Head and Neck Cancer Studies, Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Nonmelanoma Skin Cancer Studies, and T-cell and B-cell Immunology.

Recent publications reflect work in diverse venues and contemporary scientific challenges. Notable papers include:

  • Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies, 2020, published in Cell
  • Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers, 2021, published in Science Translational Medicine
  • Evolution of Cancer Vaccines-Challenges, Achievements, and Future Directions, 2021, published in Vaccines
  • Salivary High-Risk Human Papillomavirus (HPV) DNA as a Biomarker for HPV-Driven Head and Neck Cancers, 2021, published in Journal of Molecular Diagnostics
  • Oral HPV16 DNA as a screening tool to detect early oropharyngeal squamous cell carcinoma, 2020, published in Cancer Science

The scientist frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Frontiers in Immunology
  • iScience
  • Clinical & Translational Immunology

They have collaborated extensively with several researchers, including:

  • Janin Chandra, with 22 coauthored works
  • Jazmina L. Gonzalez Cruz, with 10 coauthored works
  • Zewen Kelvin Tuong, with 9 coauthored works
  • Quan Nguyen, with 9 coauthored works
  • Rahul Ladwa, with 8 coauthored works

Ian H. Frazer has been recognized with various awards, including:

  • Fellow of the Royal Society of Edinburgh, 2018
  • Fellow of the Australian Academy of Health and Medical Science, 2014
  • Fellow of the Royal Society, United Kingdom, 2011
  • International Balzan Prize, 2008
  • Prime Minister's Prize for Science, Australia, 2008, awarded for the creation of the first vaccine designed to protect against a cancer
  • Florey Medal from the Australian Institute of Policy & Science, 2006, for development of the cervical cancer vaccine Gardasil
  • Fellow of the Australian Academy of Science, 2004

Best Publications

  • Expression of vaccinia recombinant HPV 16 L1 and L2 ORF proteins in epithelial cells is sufficient for assembly of HPV virion-like particles.

    Jian Zhou;Xiao Yi Sun;Deborah J. Stenzel;Deborah J. Stenzel;Ian H. Frazer

  • Identification of the alpha6 integrin as a candidate receptor for papillomaviruses.

    Magnus Evander;Ian H. Frazer;Elizabeth Payne;Ying Mei Qi

  • Prevention of cervical cancer through papillomavirus vaccination

    Ian H. Frazer

  • Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity.

    Purnima Bhat;Graham Leggatt;Nigel J Waterhouse;Ian H Frazer

  • New gene functions in megakaryopoiesis and platelet formation

    Christian Gieger;Aparna Radhakrishnan;Ana Cvejic;Weihong Tang

  • The projected timeframe until cervical cancer elimination in Australia: a modelling study

    Michaela T. Hall;Michaela T. Hall;Kate T. Simms;Jie-Bin Lew;Megan A. Smith;Megan A. Smith

  • Chapter 12: Prophylactic HPV vaccines: underlying mechanisms.

    Margaret Stanley;Douglas R. Lowy;Ian H. Frazer

  • Papillomavirus capsid protein expression level depends on the match between codon usage and tRNA availability

    Jian Zhou;Wen Jun Liu;Shi Wen Peng;Xiao Yi Sun

  • Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

    Beben Benyamin;Manuel A.R. Ferreira;Gonneke Willemsen;Scott Gordon

  • Interaction of human papillomaviruses with the host immune system: a well evolved relationship.

    Ian H. Frazer

  • ASSOCIATION BETWEEN ANORECTAL DYSPLASIA, HUMAN PAPILLOMAVIRUS, AND HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN HOMOSEXUAL MEN

    I.H Frazer;R.M Crapper;G Medley;T.C Brown

  • A "public" T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes.

    Robert W. Tindle;Germain J. P. Fernando;Jane C. Sterling;Ian H. Frazer

  • HPV6b virus like particles are potent immunogens without adjuvant in man.

    Li Fang Zhang;Jian Zhou;Shao Chen;Lian Lian Cai

  • Genetic and environmental causes of variation in basal levels of blood cells

    David M Evans;Ian H Frazer;Nicholas G Martin

  • Papillomavirus capsid binding and uptake by cells from different tissues and species.

    M. Muller;L. Gissmann;R. J. Cristiano;Xiao-Yi Sun

  • Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin.

    Xianfeng Chen;Tarl W. Prow;Michael L. Crichton;Derek W.K. Jenkins

  • Nanopatch-targeted skin vaccination against West Nile Virus and Chikungunya virus in mice.

    Tarl W. Prow;Xianfeng Chen;Natalie A. Prow;Germain J. P. Fernando

  • Cervical cancer control, priorities and new directions.

    Joseph Monsonego;F. Xavier Bosch;Pierre Coursaget;John Thomas Cox

  • Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX adjuvant in women with cervical intraepithelial neoplasia

    Ian H Frazer;Michael Quinn;Jim L Nicklin;Jeffrey Tan

  • Papillomavirus immune evasion strategies target the infected cell and the local immune system

    Chenhao Zhou;Zewen Kelvin Tuong;Zewen Kelvin Tuong;Ian Hector Frazer

  • Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

    B. Benyamin;M. A. Ferreira;G. Willemsen;S. Gordon

Frequent Co-Authors

Germain J. P. Fernando
Germain J. P. Fernando University of Queensland
Paul F. Lambert
Paul F. Lambert University of Wisconsin–Madison
David Evans
David Evans University of Bristol
Nicholas G. Martin
Nicholas G. Martin QIMR Berghofer Medical Research Institute
Suzanne M. Garland
Suzanne M. Garland University of Melbourne
Ranjeny Thomas
Ranjeny Thomas University of Queensland
Grant W. Montgomery
Grant W. Montgomery University of Queensland
Xianfeng Chen
Xianfeng Chen University of Edinburgh
H. Peter Soyer
H. Peter Soyer University of Queensland
Manuel A. R. Ferreira
Manuel A. R. Ferreira QIMR Berghofer Medical Research Institute

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