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Immunology

D-Index
80
Citations
20170
World Ranking
1648
National Ranking
815

Medicine

D-Index
80
Citations
20135
World Ranking
17261
National Ranking
8650

Overview

Chien-Fu Hung is affiliated with Johns Hopkins University in the United States. Their research spans multiple fields including medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology. Within these areas, Hung's work focuses particularly on immunology, molecular biology, epidemiology, oncology, and infectious diseases.

The scientist has contributed significantly to several main research topics, including immunotherapy and immune responses, cervical cancer and human papillomavirus (HPV) research, cancer immunotherapy and biomarkers, SARS-CoV-2 and COVID-19 research, virus-based gene therapy research, vaccines and immunoinformatics approaches, and COVID-19 clinical research studies.

Hung's recent publications cover important advances in vaccine development and cancer immunotherapy. Notable papers include:

  • "Coronavirus vaccine development: from SARS and MERS to COVID-19" (2020) published in the Journal of Biomedical Science
  • "Cervical Cancer Immunotherapy: Facts and Hopes" (2021) published in Clinical Cancer Research
  • "COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection" (2022) published in the Journal of Biomedical Science
  • "Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody" (2021) published in mBio
  • "Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment" (2020) published in Nature Communications

Frequent co-authors of Chien-Fu Hung include:

  • T.-C. Wu (35 joint publications)
  • Richard B.S. Roden (20 joint publications)
  • Deyin Xing (17 joint publications)
  • Louise Ferrall (16 joint publications)
  • Brandon Lam (14 joint publications)

Hung's work has appeared frequently in several scientific journals, including:

  • Journal of Biomedical Science (8 publications)
  • mBio (4 publications)
  • Cancer Research (4 publications)
  • International Journal of Gynecological Pathology (3 publications)
  • Gynecologic Oncology (3 publications)

Best Publications

  • Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.

    Trevor M. Penning;Michael E. Burczynski;Joseph M. Jez;Chien-Fu Hung

  • Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones.

    Trevor M. Penning;Michael E. Burczynski;Chien Fu Hung;Kirsten D. McCoull

  • Prospects of RNA interference therapy for cancer.

    Pai Si;Lin Yy;Macaes B;Meneshian A

  • Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene.

    Chien Hung Chen;Tian Li Wang;Chien Fu Hung;Yanqin Yang

  • Coronavirus vaccine development: from SARS and MERS to COVID-19.

    Yen Der Li;Wei Yu Chi;Jun Han Su;Louise Ferrall

  • Cervical cancer immunotherapy: Facts and hopes

    Louise Ferrall;Ken Y. Lin;Richard B.S. Roden;Chien Fu Hung

  • Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen.

    Wen Fang Cheng;Chien Fu Hung;Chee Yin Chai;Keng Fu Hsu

  • Spontaneous regression of high-grade cervical dysplasia: effects of human papillomavirus type and HLA phenotype.

    Cornelia L Trimble;Steven Piantadosi;Patti Gravitt;Brigitte Ronnett

  • DNA vaccine for cancer immunotherapy

    Benjamin Yang;Jessica Jeang;Andrew Yang;T. C. Wu

  • Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.

    Meredith L. Stone;Katherine B. Chiappinelli;Huili Li;Lauren M. Murphy

  • COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

    Unknown

  • Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe

    Cornelia Trimble;Cheng Tao Lin;Cheng Tao Lin;Chien Fu Hung;Sara Pai

  • Perspectives for therapeutic HPV vaccine development

    Andrew Yang;Emily Farmer;T. C. Wu;Chien Fu Hung;Chien Fu Hung

  • Therapeutic human papillomavirus vaccines: current clinical trials and future directions

    Chien Fu Hung;Barbara Ma;Archana Monie;Shaw Wei Tsen

  • Generation and Characterization of DNA Vaccines Targeting the Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus

    Tae Woo Kim;Jin Hyup Lee;Chien Fu Hung;Shiwen Peng

  • Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins

    Tae Woo Kim;Chien Fu Hung;Morris Ling;Jeremy Juang

  • A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression.

    Adriaan D. Bins;Annelies Jorritsma;Monika C. Wolkers;Chien Fu Hung

  • Cervarix: a vaccine for the prevention of HPV 16, 18-associated cervical cancer.

    Archana Monie;Chien-Fu Hung;Richard S Roden;Tzyy Choou Wu

  • Dose-Dense Chemotherapy Improves Mechanisms of Antitumor Immune Response

    Chih Long Chang;Yun Ting Hsu;Chao Chih Wu;Yan Zen Lai

  • Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen.

    Chien-Fu Hung;Wen-Fang Cheng;Keng-Fu Hsu;Chee-Yin Chai

  • Antigen‐specific immunotherapy of cervical and ovarian cancer

    Chien Fu Hung;T. C. Wu;Archana Monie;Richard Roden

  • Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors.

    Hongxiu Ji;Tian Li Wang;Chien Hung Chen;Chien Hung Chen;Sara I. Pai

Frequent Co-Authors

Tzyy Choou Wu
Tzyy Choou Wu Johns Hopkins University
Richard B.S. Roden
Richard B.S. Roden Johns Hopkins University
Ronald D. Alvarez
Ronald D. Alvarez Vanderbilt University Medical Center
Tian Li Wang
Tian Li Wang Johns Hopkins University
Raphael P. Viscidi
Raphael P. Viscidi Johns Hopkins University
Justin Hanes
Justin Hanes Johns Hopkins University
Drew M. Pardoll
Drew M. Pardoll Johns Hopkins University School of Medicine
Brigitte M. Ronnett
Brigitte M. Ronnett Johns Hopkins University
Elizabeth M. Jaffee
Elizabeth M. Jaffee Johns Hopkins University
J. Marie Hardwick
J. Marie Hardwick Johns Hopkins University

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