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Chemistry

D-Index
86
Citations
24955
World Ranking
2561
National Ranking
896

Biology and Biochemistry

D-Index
93
Citations
33536
World Ranking
2090
National Ranking
1140

Research.com Recognitions

  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ian A. Blair is affiliated with the University of Pennsylvania in the United States. Their research spans significant areas within biochemistry, genetics, molecular biology, and medicine. The scientist's work primarily concentrates on molecular biology, oncology, cellular and molecular neuroscience, cancer research, and pulmonary and respiratory medicine.

The main topics covered in their research include:

  • Genetic neurodegenerative diseases
  • Mitochondrial function and pathology
  • Cancer, hypoxia, and metabolism
  • Advanced glycation end products research
  • Neurological disorders and treatments
  • Cancer, lipids, and metabolism
  • Ferroptosis and cancer prognosis

Key recent papers authored or co-authored by Ian A. Blair include:

  • "Lactate Limits T Cell Proliferation via the NAD(H) Redox State" (2020) published in Cell Reports
  • "FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome" (2020) published in Nature Cell Biology
  • "Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2" (2020) published in Cancer Discovery
  • "Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells" (2020) published in Science
  • "Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation" (2020) published in Cell Metabolism

Frequent coauthors who have collaborated with Ian A. Blair include Clementina Mesaros, Teerapat Rojsajjakul, David R. Lynch, Kevin P. Gillespie, and Stacy G. Wendell.

The scientist commonly publishes in the following venues:

  • Cancer Research
  • Scientific Reports
  • Communications Biology
  • Research Square (Research Square)
  • npj Breast Cancer

Ian A. Blair was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2005. This recognition aligns with their extensive work and contributions to scientific research fields mentioned above.

Best Publications

  • Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

    Gina M. DeNicola;Florian A. Karreth;Timothy J. Humpton;Aarthi Gopinathan

  • Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

    Omkar U. Kawalekar;Roddy S. O’Connor;Joseph A. Fraietta;Lili Guo

  • Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments

    Alessia Angelin;Luis Gil-de-Gómez;Satinder Dahiya;Jing Jiao

  • Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids

    J D Morrow;J A Awad;H J Boss;I A Blair

  • Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure

    Kenneth C. Bedi;Nathaniel W. Snyder;Jeffrey Brandimarto;Moez Aziz

  • Vitamin C-Induced Decomposition of Lipid Hydroperoxides to Endogenous Genotoxins

    Seon Hwa Lee;Tomoyuki Oe;Ian A. Blair

  • Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation

    Joyce V. Lee;Alessandro Carrer;Supriya Shah;Nathaniel W. Snyder

  • Detection of Endogenous Malondialdehyde-Deoxyguanosine Adducts in Human Liver

    AK Chaudhary;M Nokubo;GR Reddy;SN Yeola

  • Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

    Anthony J Covarrubias;Halil Ibrahim Aksoylar;Jiujiu Yu;Nathaniel W Snyder;Nathaniel W Snyder

  • Association of CYP3A4 genotype with treatment-related leukemia

    Carolyn A. Felix;Amy H. Walker;Beverly J. Lange;Terence M. Williams

  • Oxidation of quinidine by human liver cytochrome P-450

    F P Guengerich;D Müller-Enoch;I A Blair

  • ATP-citrate lyase controls a glucose-to-acetate metabolic switch

    Steven Zhao;AnnMarie Torres;Ryan A. Henry;Sophie Trefely

  • Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes.

    J D Morrow;T A Minton;C R Mukundan;M D Campbell

  • DNA Topoisomerase II in Therapy-Related Acute Promyelocytic Leukemia

    Anita R. Mistry;Carolyn A. Felix;Ryan J. Whitmarsh;Annabel Mason

  • Prostacyclin is not a circulating hormone in man

    I.A. Blair;S.E. Barrow;K.A. Waddell;P.J. Lewis

  • Lactate Limits T Cell Proliferation via the NAD(H) Redox State.

    William J. Quinn;Jing Jiao;Tara TeSlaa;Jason Stadanlick

  • Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.

    Nisha T. Palackal;Seon Hwa Lee;Ronald G. Harvey;Ian A. Blair

  • Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation.

    Seon Hwa Lee;Ian A. Blair

  • DNA Adducts with Lipid Peroxidation Products

    Ian A. Blair

  • Estimated rate of thromboxane secretion into the circulation of normal humans.

    C Patrono;G Ciabattoni;F Pugliese;A Pierucci

  • Stable-isotope dilution LC–MS for quantitative biomarker analysis

    Eugene Ciccimaro;Ian A Blair

  • Liquid chromatography/electron capture atmospheric pressure chemical ionization/mass spectrometry: analysis of pentafluorobenzyl derivatives of biomolecules and drugs in the attomole range.

    Gurkeerat Singh;Alejandro Gutierrez;Keyang Xu;Ian A. Blair

Frequent Co-Authors

Ronald G. Harvey
Ronald G. Harvey University of Chicago
Alexander S. Whitehead
Alexander S. Whitehead University of Pennsylvania
Jorge H. Capdevila
Jorge H. Capdevila Vanderbilt University
David A. Lynch
David A. Lynch Children's Hospital of Philadelphia
Garret A. FitzGerald
Garret A. FitzGerald University of Pennsylvania
John R. Falck
John R. Falck The University of Texas Southwestern Medical Center
Carolyn A. Felix
Carolyn A. Felix Children's Hospital of Philadelphia
Jerry D. Glickson
Jerry D. Glickson University of Pennsylvania
Lawrence J. Marnett
Lawrence J. Marnett Vanderbilt University
Ellen Puré
Ellen Puré University of Pennsylvania

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