World's Best Scientists 2026 revealed!
Lawrence J. Marnett

Lawrence J. Marnett

D-Index & Metrics

Chemistry

D-Index
123
Citations
56156
World Ranking
436
National Ranking
187

Biology and Biochemistry

D-Index
127
Citations
60243
World Ranking
469
National Ranking
302

Research.com Recognitions

  • 2010 - Fellow of the American Chemical Society
  • 2001 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Lawrence J. Marnett is affiliated with Vanderbilt University in the United States and has made contributions primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research covers pharmacology, molecular biology, cellular and molecular neuroscience, cancer research, and organic chemistry.

Their scientific work centers on several main topics, including:

  • Inflammatory mediators and NSAID effects
  • Cannabis and cannabinoid research
  • Neurotransmitter receptor influence on behavior
  • Eicosanoids and hypertension pharmacology
  • Estrogen and related hormone effects
  • DNA repair mechanisms
  • Neuroinflammation and neurodegeneration mechanisms

Among recent notable papers authored or co-authored by Lawrence J. Marnett are:

  • Structural and Chemical Biology of the Interaction of Cyclooxygenase with Substrates and Non-Steroidal Anti-Inflammatory Drugs, 2020, Chemical Reviews
  • In vivo endocannabinoid dynamics at the timescale of physiological and pathological neural activity, 2021, Neuron
  • Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa, 2020, Gut
  • Enhancing endocannabinoid signalling in astrocytes promotes recovery from traumatic brain injury, 2021, Brain
  • Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models, 2021, Journal of Clinical Investigation

This scientist frequently publishes in venues such as Free Radical Biology and Medicine, bioRxiv (Cold Spring Harbor Laboratory), ACS Medicinal Chemistry Letters, Chemical Research in Toxicology, and ACS Chemical Biology.

Collaborations have been established with several researchers, including:

  • Philip J. Kingsley
  • Md. Jashim Uddin
  • Brenda C. Crews
  • Carol A. Rouzer
  • Sachin Patel

Lawrence J. Marnett has been recognized as a Fellow by prominent scientific organizations, including the American Chemical Society in 2010 and the American Association for the Advancement of Science (AAAS) in 2001.

Best Publications

  • Oxyradicals and DNA damage

    Lawrence J. Marnett

  • Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors

    Marja D. Van Sickle;Marnie Duncan;Philip J. Kingsley;Abdeslam Mouihate

  • Lipid peroxidation—DNA damage by malondialdehyde

    Lawrence J. Marnett

  • Pharmacodynamic and Pharmacokinetic Study of Oral Curcuma Extract in Patients with Colorectal Cancer

    Ricky A. Sharma;Heather R. McLelland;Kirsti A. Hill;Christopher R. Ireson

  • Aspirin and the Potential Role of Prostaglandins in Colon Cancer

    Lawrence J. Marnett

  • Prostaglandin endoperoxide synthase : structure and catalysis

    William L. Smith;Lawrence J. Marnett

  • Biomarkers of oxidative stress study II : are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?

    M.B. Kadiiska;B.C. Gladen;D.D. Baird;D. Germolec

  • Cyclooxygenases: structural and functional insights

    Carol A. Rouzer;Lawrence J. Marnett

  • Oxy radicals, lipid peroxidation and DNA damage

    Lawrence J Marnett

  • Malondialdehyde, a Product of Lipid Peroxidation, Is Mutagenic in Human Cells

    Laura J. Niedernhofer;J. Scott Daniels;Carol A. Rouzer;Rachel E. Greene

  • Naturally occurring carbonyl compounds are mutagens in Salmonella tester strain TA104.

    Lawrence J. Marnett;Holly K. Hurd;Monica C. Hollstein;David E. Levin

  • Arachidonic Acid Oxygenation by COX-1 and COX-2 MECHANISMS OF CATALYSIS AND INHIBITION

    Lawrence J. Marnett;Scott W. Rowlinson;Douglas C. Goodwin;Amit S. Kalgutkar

  • Structural and functional basis of cyclooxygenase inhibition.

    Anna L Blobaum;Lawrence J Marnett

  • Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis

    Lisa M. Landino;Brenda C. Crews;Michael D. Timmons;Jason D. Morrow

  • Prostaglandin and thromboxane biosynthesis.

    William L. Smith;Lawrence J. Marnett;David L. DeWitt

  • Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein

    Lawrence J. Marnett;James N. Riggins;James D. West

  • Oxygenation of the Endocannabinoid, 2-Arachidonylglycerol, to Glyceryl Prostaglandins by Cyclooxygenase-2

    Kevin R. Kozak;Scott W. Rowlinson;Lawrence J. Marnett

  • Detection of Endogenous Malondialdehyde-Deoxyguanosine Adducts in Human Liver

    AK Chaudhary;M Nokubo;GR Reddy;SN Yeola

  • Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors.

    Amit S. Kalgutkar;Alan B. Marnett;Brenda C. Crews;Rory P. Remmel

  • COX-2: A Target for Colon Cancer Prevention

    Lawrence J. Marnett;Raymond N. DuBois

Frequent Co-Authors

Amit S. Kalgutkar
Amit S. Kalgutkar Pfizer (United States)
Sachin Patel
Sachin Patel Vanderbilt University Medical Center
Robert L. Smith
Robert L. Smith Imperial College London
Samuel Monroe Cohen
Samuel Monroe Cohen University of Nebraska Medical Center
Philip S. Portoghese
Philip S. Portoghese University of Minnesota
Jason D. Morrow
Jason D. Morrow Vanderbilt University
Ned A. Porter
Ned A. Porter Vanderbilt University
Kenneth V. Honn
Kenneth V. Honn Wayne State University
Ivonne M.C.M. Rietjens
Ivonne M.C.M. Rietjens Wageningen University & Research
John A. Oates
John A. Oates Vanderbilt University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in pursuing a Chemistry degree in the USA, exploring related fields can open diverse career opportunities. One such pathway is forensic science, which blends chemistry principles with criminal investigations. Many universities now offer forensic science online degree programs that provide flexible learning options without compromising quality.

For graduates seeking advanced specialization, forensic psychology graduate programs online are increasingly popular. These programs emphasize the psychological aspects behind criminal behavior, complementing a strong science background.

When considering these degrees, understanding the financial outcomes is crucial. Those with a forensic science degree can expect competitive salaries, as detailed in forensic science degree salary insights. Additionally, prospective students evaluating costs should review information on how much is criminal justice degree programs, which often overlap with forensic disciplines.

Overall, branching into forensic science, psychology, or criminal justice through affordable online degrees can provide strong career paths tied closely to the foundations laid in chemistry studies.

Best Scientists Citing Lawrence J. Marnett

Trending Scientists

Recently Published Articles