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Neuroscience

D-Index
56
Citations
10712
World Ranking
4534
National Ranking
2046

Overview

Sachin Patel is a researcher affiliated with Vanderbilt University Medical Center in the United States. Their work spans the fields of Neuroscience and Medicine, with a strong emphasis on subfields such as Cellular and Molecular Neuroscience, Pharmacology, and Cognitive Neuroscience. The scope of their research also touches on Molecular Biology and Social Psychology.

The main topics of Sachin Patel's research include Cannabis and Cannabinoid Research, Neuroscience and Neuropharmacology Research, and Neurotransmitter Receptor Influence on Behavior. Additional areas of focus are Sleep and Wakefulness Research, Receptor Mechanisms and Signaling, Neuroendocrine Regulation and Behavior, and Alcohol Consumption and Health Effects.

Frequent publication venues for their research include Neuropsychopharmacology, bioRxiv (Cold Spring Harbor Laboratory), Biological Psychiatry, Neuron, and Cell Reports.

Recent papers authored in collaboration with other researchers cover a range of topics related to neural mechanisms and endocannabinoid systems:

  • Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening, 2020, Neuron
  • In vivo endocannabinoid dynamics at the timescale of physiological and pathological neural activity, 2021, Neuron
  • 2-Arachidonoylglycerol Modulation of Anxiety and Stress Adaptation: From Grass Roots to Novel Therapeutics, 2020, Biological Psychiatry
  • A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction, 2023, Neuron
  • BNST PKCδ neurons are activated by specific aversive conditions to promote anxiety-like behavior, 2023, Neuropsychopharmacology

Collaborative work is an important element of their research profile. The most frequent co-authors include Veronika Kondev, Nathan D. Winters, Danny G. Winder, Brad A. Grueter, and Luis E. Rosas-Vidal.

Best Publications

  • Neurobiological Interactions Between Stress and the Endocannabinoid System.

    Maria Morena;Sachin Patel;Jaideep S Bains;Matthew N Hill;Matthew N Hill

  • Endocannabinoid Signaling Negatively Modulates Stress-Induced Activation of the Hypothalamic-Pituitary-Adrenal Axis

    Sachin Patel;Craig T. Roelke;David J. Rademacher;William E. Cullinan

  • Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling.

    Sachin Patel;Cecilia J Hillard

  • Downregulation of Endocannabinoid Signaling in the Hippocampus Following Chronic Unpredictable Stress

    Matthew N Hill;Sachin Patel;Erica J Carrier;David J Rademacher

  • Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling.

    Sachin Patel;Craig T. Roelke;David J. Rademacher;Cecilia J. Hillard

  • Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.

    O. Gunduz-Cinar;K. P. MacPherson;R. Cinar;J. Gamble-George

  • Functional Interactions between Stress and the Endocannabinoid System: From Synaptic Signaling to Behavioral Output

    Matthew N. Hill;Sachin Patel;Patrizia Campolongo;Jeffrey G. Tasker

  • Prefrontal inputs to the amygdala instruct fear extinction memory formation.

    Olena Bukalo;Courtney R. Pinard;Shana Silverstein;Shana Silverstein;Christina Brehm

  • Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability

    Khyobeni Mozhui;Rose Marie Karlsson;Thomas L. Kash;Jessica Ihne

  • Corticotropin-Releasing Hormone Drives Anandamide Hydrolysis in the Amygdala to Promote Anxiety

    J. Megan Gray;Haley A. Vecchiarelli;Maria Morena;Tiffany T. Y. Lee

  • The endocannabinoid system as a target for novel anxiolytic drugs

    Sachin Patel;Mathew N. Hill;Joseph F. Cheer;Carsten T. Wotjak

  • Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder.

    Matthew N Hill;Patrizia Campolongo;Rachel Yehuda;Sachin Patel

  • The Therapeutic Potential of the Endocannabinoid System for the Development of a Novel Class of Antidepressants

    Matthew N. Hill;Cecilia J. Hillard;Francis R. Bambico;Sachin Patel;Sachin Patel

  • Adaptations in endocannabinoid signaling in response to repeated homotypic stress: a novel mechanism for stress habituation.

    Sachin Patel;Cecilia J. Hillard

  • Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala.

    Sachin Patel;Benjamin F Cravatt;Cecilia J Hillard

  • Genetic Disruption of 2-Arachidonoylglycerol Synthesis Reveals a Key Role for Endocannabinoid Signaling in Anxiety Modulation

    Brian C. Shonesy;Rebecca J. Bluett;Teniel S. Ramikie;Rita Báldi

  • Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation.

    R J Bluett;J C Gamble-George;D J Hermanson;N D Hartley

  • Differential Regulation of the Endocannabinoids Anandamide and 2-Arachidonylglycerol within the Limbic Forebrain by Dopamine Receptor Activity

    Sachin Patel;David J. Rademacher;Cecilia J. Hillard

  • Repeated Homotypic Stress Elevates 2-Arachidonoylglycerol Levels and Enhances Short-Term Endocannabinoid Signaling at Inhibitory Synapses in Basolateral Amygdala

    Sachin Patel;Philip J Kingsley;Ken Mackie;Lawrence J Marnett

  • The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase.

    Sachin Patel;Eric R Wohlfeil;David J Rademacher;Erica J Carrier

  • DOI-Induced Activation of the Cortex: Dependence on 5-HT2A Heteroceptors on Thalamocortical Glutamatergic Neurons

    Jennifer L. Scruggs;Sachin Patel;Michael Bubser;Ariel Y. Deutch

Frequent Co-Authors

Danny G. Winder
Danny G. Winder Vanderbilt University
Matthew N. Hill
Matthew N. Hill University of Calgary
Ken Mackie
Ken Mackie Indiana University
Carla Dalmaz
Carla Dalmaz Federal University of Rio Grande do Sul
Thomas L. Kash
Thomas L. Kash University of North Carolina at Chapel Hill
Carl R. Lupica
Carl R. Lupica National Institute on Drug Abuse
Quentin J. Pittman
Quentin J. Pittman University of Calgary
Carsten T. Wotjak
Carsten T. Wotjak Max Planck Society
Boris B. Gorzalka
Boris B. Gorzalka University of British Columbia
Robert W. Williams
Robert W. Williams University of Tennessee Health Science Center

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