2016 - Fellow of the American Association for the Advancement of Science (AAAS)
His primary areas of investigation include Cannabinoid receptor, Cannabinoid, Neuroscience, Endocannabinoid system and Receptor. The study incorporates disciplines such as Endocrinology and Pharmacology in addition to Cannabinoid receptor. His Pharmacology research is multidisciplinary, incorporating perspectives in Cannabinoid Receptor Modulators, AM251, Agonist, Functional selectivity and Enzyme-linked receptor.
The Cannabinoid study combines topics in areas such as Neuroinflammation, Calcium channel, Anandamide, Angiotensin II and Vasodilation. His Endocannabinoid system study integrates concerns from other disciplines, such as Nervous system, gamma-Aminobutyric acid, Metabotropic receptor, Depolarization-induced suppression of inhibition and Long-term depression. His research investigates the link between Receptor and topics such as Cell biology that cross with problems in Biochemistry.
His primary scientific interests are in Cannabinoid receptor, Endocannabinoid system, Cannabinoid, Neuroscience and Receptor. His Cannabinoid receptor research integrates issues from Endocrinology, Pharmacology and Cell biology. The Endocannabinoid system study combines topics in areas such as Cannabinoid receptor type 1, Signal transduction and Fatty acid amide hydrolase.
His biological study deals with issues like Hippocampus, which deal with fields such as Hippocampal formation. His research in Neuroscience intersects with topics in Synaptic plasticity, Postsynaptic potential and Neurotransmission. His primary area of study in Receptor is in the field of Internalization.
Ken Mackie focuses on Endocannabinoid system, Cannabinoid receptor, Cannabinoid, Receptor and Pharmacology. He has researched Endocannabinoid system in several fields, including Anandamide, Endocrinology, Prefrontal cortex and Neuroscience. The study incorporates disciplines such as Glutamate receptor and Synaptic plasticity in addition to Neuroscience.
His Cannabinoid receptor study incorporates themes from Cerebellum and Hippocampal formation. His Cannabinoid research also works with subjects such as
His primary areas of study are Cannabinoid receptor, Endocannabinoid system, Cannabinoid, Pharmacology and Internal medicine. He is doing genetic studies as part of his Receptor and Biochemistry and Cannabinoid receptor investigations. His Endocannabinoid system research includes themes of Glutamatergic, Prefrontal cortex, Anandamide and Hippocampus, Neuroscience.
The concepts of his Cannabinoid study are interwoven with issues in Rimonabant, Cannabinoid receptor type 2, Allosteric modulator, Pulmonary fibrosis and Cannabinoid receptor type 1. His Pharmacology research is multidisciplinary, relying on both Agonist and Pathogenesis. His Internal medicine study integrates concerns from other disciplines, such as Endocrinology, Orexin-A and Lipidomics.
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International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors
A C Howlett;F Barth;T I Bonner;G Cabral.
Pharmacological Reviews (2002)
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system.
K Tsou;S Brown;M.C Sañudo-Peña;K Mackie.
Neuroscience (1998)
Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors
Marja D. Van Sickle;Marnie Duncan;Philip J. Kingsley;Abdeslam Mouihate.
Science (2005)
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2
Roger Guy Pertwee;A. C. Howlett;M. E. Abood;S. P. H. Alexander.
Pharmacological Reviews (2010)
Presynaptically Located CB1 Cannabinoid Receptors Regulate GABA Release from Axon Terminals of Specific Hippocampal Interneurons
István Katona;Beáta Sperlágh;Attila Sı́k;Attila Käfalvi.
The Journal of Neuroscience (1999)
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
Douglas Osei-Hyiaman;Michael DePetrillo;Pál Pacher;Jie Liu.
Journal of Clinical Investigation (2005)
Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.
C. C. Felder;K. E. Joyce;E. M. Briley;Jaleh Mansouri.
Molecular Pharmacology (1995)
Modulation of Ca2+ channels by G-protein beta gamma subunits.
Stefan Herlitze;David E. Garcia;David E. Garcia;Ken Mackie;Bertil Hille.
Nature (1996)
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.
Ken Mackie;Bertil Hille.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor
K Mackie;Y Lai;R Westenbroek;R Mitchell.
The Journal of Neuroscience (1995)
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