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Neuroscience

D-Index
40
Citations
9552
World Ranking
7988
National Ranking
3431

Overview

Hui-Chen Lu is a researcher affiliated with Indiana University in the United States, specializing in multiple related fields including neuroscience, medicine, and biochemistry, genetics, and molecular biology. The scientist's work spans diverse areas within these domains, with a particular focus on cellular and molecular neuroscience, molecular biology, pediatrics, perinatology, child health, cognitive neuroscience, and pharmacology.

Among the main topics explored in their research are prenatal substance exposure effects, cannabis and cannabinoid research, neuroscience and neuropharmacology research, neural dynamics and brain function, 3D printing in biomedical research, mitochondrial function and pathology, and the neuroscience of respiration and sleep.

Hui-Chen Lu has contributed to a variety of scientific publications. Notable papers include:

  • Review of the Endocannabinoid System, 2020, Biological Psychiatry Cognitive Neuroscience and Neuroimaging
  • Tubular human brain organoids to model microglia-mediated neuroinflammation, 2021, Lab on a Chip
  • Axonal energy metabolism, and the effects in aging and neurodegenerative diseases, 2023, Molecular Neurodegeneration
  • Acoustofluidic assembly of 3D neurospheroids to model Alzheimer's disease, 2020, The Analyst
  • Prenatal methadone exposure disrupts behavioral development and alters motor neuron intrinsic properties and local circuitry, 2021, eLife

The scientist frequently publishes in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Neurodegeneration
  • Drug Metabolism and Pharmacokinetics
  • Biological Psychiatry Cognitive Neuroscience and Neuroimaging
  • Lab on a Chip

Collaboration forms an important part of Hui-Chen Lu's work, with frequent co-authors being:

  • Jui-Yen Huang
  • Ken Mackie
  • Hongwei Cai
  • Feng Guo
  • Sen Yang

The scientist's research has produced a significant volume of publications in neuroscience and related fields, contributing to the understanding of prenatal substance exposure and the endocannabinoid system, among other areas. Their interdisciplinary approach combines elements of developmental neuroscience, neuropharmacology, and biomedical engineering techniques to address complex biological questions.

Best Publications

  • An Introduction to the Endogenous Cannabinoid System.

    Hui-Chen Lu;Ken Mackie

  • Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

    Hsiao Tuan Chao;Hongmei Chen;Rodney C. Samaco;Mingshan Xue;Mingshan Xue

  • GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

    Jane E. Lauckner;Jill B. Jensen;Huei Ying Chen;Hui Chen Lu

  • NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease

    Hong Lian;Li Yang;Allysa Cole;Lu Sun

  • Activity-dependent decrease of excitability in rat hippocampal neurons through increases in Ih

    Yuan Fan;Desdemona Fricker;Darrin H. Brager;Xixi Chen

  • Review of the Endocannabinoid System

    Hui-Chen Lu;Ken Mackie

  • SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties

    Kihoon Han;Kihoon Han;J. Lloyd Holder;J. Lloyd Holder;Christian P. Schaaf;Christian P. Schaaf;Hui Lu;Hui Lu

  • Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning.

    Jan Mulder;Tania Aguado;Erik Keimpema;Klaudia Barabás

  • Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain

    Chia-Shan Wu;Christopher P Jew;Christopher P Jew;Hui-Chen Lu

  • Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition.

    Hui-Chen Lu;Ernesto Gonzalez;Michael C Crair

  • Correction: Corrigendum: Screening with an NMNAT2-MSD platform identifies small molecules that modulate NMNAT2 levels in cortical neurons

    Yousuf O. Ali;Gillian Bradley;Hui-Chen Lu

  • Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections.

    Chia-Shan Wu;Jie Zhu;Jim Wager-Miller;Shan Wang

  • Visualization of gene expression patterns by in situ hybridization.

    Urs Albrecht;Gregor Eichele;Jill A. Helms;Hui-Chen Lu

  • CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

    M. Cecilia Ljungberg;Yousuf O. Ali;Jie Zhu;Chia Shan Wu

  • Strain background influences neurotoxicity and behavioral abnormalities in mice expressing the tetracycline transactivator.

    Harry J. Han;Carolyn C. Allen;Christie M. Buchovecky;Michael J. Yetman

  • Adenylyl cyclase I regulates AMPA receptor trafficking during mouse cortical 'barrel' map development.

    Hui Chen Lu;Wei Chi She;Daniel T. Plas;Paul E. Neumann

  • GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.

    Chia-Shan Wu;Hongmei Chen;Hao Sun;Jie Zhu

  • The Amyloid Precursor Protein Controls Adult Hippocampal Neurogenesis through GABAergic Interneurons

    Baiping Wang;Zilai Wang;Lu Sun;Li Yang

  • Rescue of Drosophila labial null mutant by the chicken ortholog Hoxb-1 demonstrates that the function of Hox genes is phylogenetically conserved.

    B. Lutz;Hui-Chen Lu;G. Eichele;D. Miller

  • The CB1 cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis

    Javier Díaz-Alonso;Tania Aguado;Chia-Shan Wu;Javier Palazuelos

  • Biphasic cholinergic synaptic transmission controls action potential activity in thalamic reticular nucleus neurons

    Yan Gang Sun;Juan D. Pita-Almenar;Chia Shan Wu;John J. Renger

Frequent Co-Authors

Ken Mackie
Ken Mackie Indiana University
Michael C. Crair
Michael C. Crair Yale University
Beat Lutz
Beat Lutz Johannes Gutenberg University of Mainz
Huda Y. Zoghbi
Huda Y. Zoghbi Baylor College of Medicine
Hui Zheng
Hui Zheng Baylor College of Medicine
John J. Renger
John J. Renger MSD (United States)
Hugo J. Bellen
Hugo J. Bellen Baylor College of Medicine
François Guillemot
François Guillemot The Francis Crick Institute
Daniel Johnston
Daniel Johnston The University of Texas at Austin
Philip L. De Jager
Philip L. De Jager Columbia University

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