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Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
29225
World Ranking
1851
National Ranking
23

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

Manuel Guzmán is affiliated with the Complutense University of Madrid in Spain. Their research spans primarily across Medicine and Neuroscience, with significant contributions to several subfields including Pharmacology, Cellular and Molecular Neuroscience, Surgery, Molecular Biology, and Genetics.

The scientist's work covers various topics, with a focus on Cannabis and Cannabinoid Research, Neuroscience and Neuropharmacology Research, Pancreatic function and diabetes, Neurogenesis and neuroplasticity mechanisms, Neurotransmitter Receptor Influence on Behavior, GABA and Rice Research, and COVID-19 Clinical Research Studies.

Recent publications by Manuel Guzmán include:

  • Glucose metabolism links astroglial mitochondria to cannabinoid effects, 2020, Nature
  • Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure, 2020, Neuropsychopharmacology
  • Possible therapeutic applications of cannabis in the neuropsychopharmacology field, 2020, European Neuropsychopharmacology
  • Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease, 2020, eLife
  • Δ9-Tetrahydrocannabinol promotes oligodendrocyte development and CNS myelination in vivo, 2020, Glia

Frequent coauthors of Manuel Guzmán include:

  • Ismael Galve-Roperh
  • Carlos Costas-Insua
  • Luigi Bellocchio
  • Ignacio Rodrı́guez-Crespo
  • Giovanni Marsicano

Preferred publication venues feature:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Glia
  • Journal of Neuroscience
  • IBRO Neuroscience Reports
  • eLife

Manuel Guzmán's research encompasses detailed studies of molecular and cellular mechanisms, especially those connected with cannabinoid effects on neural and metabolic functions. The scientist's body of work incorporates investigation into therapeutic targets for neurological conditions and analysis of spatial memory influenced by prenatal exposure to cannabinoids.

Best Publications

  • Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation

    Belén G Ramírez;Cristina Blázquez;Teresa Gómez del Pulgar;Manuel Guzmán

  • Cannabinoids: potential anticancer agents

    Manuel Guzmán

  • Leptin Induces Mitochondrial Superoxide Production and Monocyte Chemoattractant Protein-1 Expression in Aortic Endothelial Cells by Increasing Fatty Acid Oxidation via Protein Kinase A

    Sho Ichi Yamagishi;Diane Edelstein;Xue Liang Du;Yasufumi Kaneda

  • Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation.

    Ismael Galve-Roperh;Cristina Sánchez;María Luisa Cortés;Marta Izquierdo

  • Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

    María Salazar;Arkaitz Carracedo;Íñigo J. Salanueva;Sonia Hernández-Tiedra

  • Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor

    Cristina Sánchez;María L. de Ceballos;Teresa Gómez del Pulgar;Daniel Rueda

  • Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors

    M. Llanos Casanova;Cristina Blázquez;Jesús Martínez-Palacio;Concepción Villanueva

  • A pilot clinical study of Δ9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme

    M Guzmán;M J Duarte;C Blázquez;J Ravina

  • The emerging functions of endocannabinoid signaling during CNS development

    Tibor Harkany;Manuel Guzmán;Ismael Galve-Roperh;Paul Berghuis

  • Towards the use of cannabinoids as antitumour agents.

    Guillermo Velasco;Guillermo Velasco;Cristina Sánchez;Manuel Guzmán

  • Cannabinoid CB2 receptor: a new target for controlling neural cell survival?

    Javier Fernández-Ruiz;Julián Romero;Guillermo Velasco;Rosa M. Tolón

  • Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

    Javier Palazuelos;Tania Aguado;M. Ruth Pazos;Boris Julien

  • Cannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes

    Arkaitz Carracedo;Meritxell Gironella;Mar Lorente;Stephane Garcia

  • The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells

    Arkaitz Carracedo;Mar Lorente;Ainara Egia;Cristina Blázquez

  • The endocannabinoid system drives neural progenitor proliferation

    Tania Aguado;Krisztina Monory;Javier Palazuelos;Nephi Stella

  • Inhibition of tumor angiogenesis by cannabinoids

    Cristina Blázquez;M. Llanos Casanova;Anna Planas;Teresa Gómez del Pulgar

  • Oleoylethanolamide Stimulates Lipolysis by Activating the Nuclear Receptor Peroxisome Proliferator-activated Receptor α (PPAR-α)

    Manuel Guzmán;Jesse Lo Verme;Jin Fu;Fariba Oveisi

  • Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning.

    Jan Mulder;Tania Aguado;Erik Keimpema;Klaudia Barabás

  • A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma

    Sofía Torres;Mar Lorente;Fátima Rodríguez-Fornés;Sonia Hernández-Tiedra

  • Δ9-Tetrahydrocannabinol induces apoptosis in C6 glioma cells

    Cristina Sánchez;Ismael Galve-Roperh;Cecile Canova;Philippe Brachet

Frequent Co-Authors

Ismael Galve-Roperh
Ismael Galve-Roperh Complutense University of Madrid
Guillermo Velasco
Guillermo Velasco Complutense University of Madrid
Arkaitz Carracedo
Arkaitz Carracedo University of the Basque Country
Giovanni Marsicano
Giovanni Marsicano University of Bordeaux
Beat Lutz
Beat Lutz Johannes Gutenberg University of Mainz
Javier Fernández-Ruiz
Javier Fernández-Ruiz Complutense University of Madrid
Enric I. Canela
Enric I. Canela University of Barcelona
Gema Moreno-Bueno
Gema Moreno-Bueno The University of Texas MD Anderson Cancer Center
Carmen Lluis
Carmen Lluis University of Barcelona
Miguel Quintanilla
Miguel Quintanilla Spanish National Research Council

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