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Enric I. Canela

Enric I. Canela

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Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
13678
World Ranking
8340
National Ranking
141

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

Enric I. Canela is affiliated with the University of Barcelona in Spain and has contributed extensively to the fields of biochemistry, genetics, molecular biology, neuroscience, and medicine. Their research spans multiple subfields, including cellular and molecular neuroscience, molecular biology, pharmacology, plant science, and surgery.

Their scientific work covers several main topics, notably cannabis and cannabinoid research, neurotransmitter receptor influence on behavior, neuroscience and neuropharmacology research, receptor mechanisms and signaling, GABA and rice research, pancreatic function and diabetes, and protein degradation and inhibitors.

Enric I. Canela has published research in a variety of scientific venues. Frequent publication outlets include NeuroTarget, with three publications, as well as eLife, Cancers, Schizophrenia Bulletin, and the International Journal of Molecular Sciences.

Among their recent papers are the following:

  • "Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease" (2020, eLife)
  • "The Interplay between Cancer Biology and the Endocannabinoid System-Significance for Cancer Risk, Prognosis and Response to Treatment" (2020, Cancers)
  • "Altered Signaling in CB1R-5-HT2AR Heteromers in Olfactory Neuroepithelium Cells of Schizophrenia Patients is Modulated by Cannabis Use" (2020, Schizophrenia Bulletin)
  • "Functional Fine-Tuning of Metabolic Pathways by the Endocannabinoid System-Implications for Health and Disease" (2021, International Journal of Molecular Sciences)
  • "Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43" (2023, Nature Communications)

Frequent collaborators of Enric I. Canela include Estefanía Moreno, Vicent Casadó, Manuel Guzmán, Irene B. Maroto, and Carlos Costas-Insua. This network of co-authors has contributed to advancing research in the neurosciences and related molecular biology areas.

Best Publications

  • Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers

    Francisco Ciruela;Vicent Casadó;Ricardo J. Rodrigues;Rafael Luján

  • Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

    Joëlle A. Hillion;Meritxell Canals;Maria Torvinen;Vicent Casado

  • Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes

    Silvia Ginés;Joëlle Hillion;Maria Torvinen;Stèphane Le Crom

  • Detection of heteromerization of more than two proteins by sequential BRET-FRET.

    Paulina Carriba;Gemma Navarro;Francisco Ciruela;Sergi Ferré

  • Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids.

    Paulina Carriba;Oskar Ortiz;Kshitij Patkar;Zuzana Justinova;Zuzana Justinova

  • Cell surface adenosine deaminase: Much more than an ectoenzyme

    Rafael Franco;Vicent Casadó;Francisco Ciruela;Carles Saura

  • Cannabinoid receptors CB1 and CB2 form functional heteromers in brain.

    Lucía Callén;Lucía Callén;Estefanía Moreno;Estefanía Moreno;Pedro Barroso-Chinea;David Moreno-Delgado;David Moreno-Delgado

  • A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation.

    Ester Angulo;Vicent Casadó;Josefa Mallol;Enric I. Canela

  • Metabotropic Glutamate 1α and Adenosine A1 Receptors Assemble into Functionally Interacting Complexes

    Francisco Ciruela;Francisco Ciruela;Marisol Escriche;Javier Burgueño;Ester Angulo

  • Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors.

    Xavier Viñals;Estefanía Moreno;Laurence Lanfumey;Arnau Cordomí

  • Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer.

    Meritxell Canals;Javier Burgueño;Daniel Marcellino;Núria Cabello

  • ADENOSINE DEAMINASE AFFECTS LIGAND-INDUCED SIGNALLING BY INTERACTING WITH CELL SURFACE ADENOSINE RECEPTORS

    Francisco Ciruela;Carles Saura;Enric I. Canela;Josefa Mallol

  • Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function.

    Carla Ferrada;Sergi Ferré;Vicent Casadó;Antonio Cortés

  • Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB2 Receptors

    Eva Martínez-Pinilla;Katia Varani;Irene Reyes-Resina;Edgar Angelats;Edgar Angelats

  • Direct involvement of σ-1 receptors in the dopamine D1 receptor-mediated effects of cocaine

    Gemma Navarro;Estefanía Moreno;Marisol Aymerich;Daniel Marcellino

  • Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

    Sergio González;David Moreno-Delgado;Estefanía Moreno;Kamil Pérez-Capote

  • Immunological identification of A1 adenosine receptors in brain cortex

    F. Ciruela;V. Casadó;J. Mallol;E. I. Canela

  • Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors.

    Carla Ferrada;Estefanía Moreno;Vicent Casadó;Gerold Bongers

  • Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer

    Jordi Bonaventura;Jordi Bonaventura;Gemma Navarro;Verònica Casadó-Anguera;Karima Azdad

  • Adenosine-cannabinoid receptor interactions. Implications for striatal function.

    Sergi Ferré;Carme Lluís;Zuzana Justinova;Zuzana Justinova;César Quiroz

Frequent Co-Authors

Rafael Franco
Rafael Franco University of Barcelona
Josefa Mallol
Josefa Mallol University of Barcelona
Vicent Casadó
Vicent Casadó University of Barcelona
Carmen Lluis
Carmen Lluis University of Barcelona
Sergi Ferré
Sergi Ferré National Institute on Drug Abuse
Gemma Navarro
Gemma Navarro University of Barcelona
Francisco Ciruela
Francisco Ciruela University of Barcelona
Kjell Fuxe
Kjell Fuxe Karolinska Institute
Marta Cascante
Marta Cascante University of Barcelona
Modesto Orozco
Modesto Orozco University of Barcelona

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