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Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
18917
World Ranking
5940
National Ranking
92

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

Marta Cascante is affiliated with the University of Barcelona in Spain. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine. The scientist has contributed extensively to subfields such as molecular biology, cancer research, oncology, immunology, and pulmonary and respiratory medicine.

The central topics of Marta Cascante's research include:

  • Cancer, Hypoxia, and Metabolism
  • Cancer Immunotherapy and Biomarkers
  • Mitochondrial Function and Pathology
  • Metabolism, Diabetes, and Cancer
  • Microbial Metabolic Engineering and Bioproduction
  • Metabolomics and Mass Spectrometry Studies
  • Epigenetics and DNA Methylation

The scientist has published in a variety of venues, frequently contributing to:

  • International Journal of Molecular Sciences
  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Obstetrics and Gynecology
  • Nature Communications

Among recent papers associated with Marta Cascante are:

  • Metabolomics: The Stethoscope for the Twenty-First Century, 2020, Medical Principles and Practice
  • The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia, 2022, Nature Communications
  • Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability, 2022, Nature Communications
  • Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation, 2020, Journal of Biological Chemistry
  • Oxidative Pentose Phosphate Pathway Enzyme 6-Phosphogluconate Dehydrogenase Plays a Key Role in Breast Cancer Metabolism, 2021, Biology

Frequent collaborators with Marta Cascante include:

  • Silvia Marín
  • Carles Foguet
  • Timothy M. Thomson
  • Joan Maurel
  • Josep Tarragó-Celada

Over the course of their career, Marta Cascante has contributed to advancing understanding in areas involving complex metabolic pathways related to cancer and other diseases. Their work involves detailed molecular investigations often intersecting cancer metabolism, metabolic vulnerabilities, and biochemical pathways.

Best Publications

  • Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

    Juan-Carlos Rodríguez-Prados;Paqui G. Través;Jimena Cuenca;Daniel Rico

  • A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence

    Joanna Kaplon;Liang Zheng;Katrin Meissl;Barbara Chaneton

  • Metabolomics enables precision medicine: "A White Paper, Community Perspective"

    Richard D. Beger;Warwick Dunn;Michael A. Schmidt;Steven S. Gross

  • Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

    Sandra Schoors;Katrien De Bock;Anna Rita Cantelmo;Maria Georgiadou

  • Targeting cell cycle regulation in cancer therapy.

    Santiago Diaz-Moralli;Míriam Tarrado-Castellarnau;Anibal Miranda;Marta Cascante

  • Metabolic control analysis in drug discovery and disease

    Marta Cascante;Laszlo G. Boros;Begoña Comin-Anduix;Pedro de Atauri

  • Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation

    L. G. Boros;J. Puigjaner;M. Cascante;W.-N. P. Lee

  • Valorization of grape (Vitis vinifera) byproducts. Antioxidant and biological properties of polyphenolic fractions differing in procyanidin composition and flavonol content.

    Josep Lluis Torres;Begona Varela;Maria Teresa Garcia;Josep Carilla

  • The puzzle of the Krebs citric acid cycle: assembling the pieces of chemically feasible reactions, and opportunism in the design of metabolic pathways during evolution.

    Enrique Meléndez-Hevia;Thomas G. Waddell;Marta Cascante

  • Oxythiamine and dehydroepiandrosterone induce a G1 phase cycle arrest in Ehrlich's tumor cells through inhibition of the pentose cycle.

    Badr Raı̈s;Begoña Comin;Joaquim Puigjaner;James L Brandes

  • Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose

    Wai-Nang Paul Lee;Laszlo G. Boros;Joaquim Puigjaner;Sara Bassilian

  • The effect of thiamine supplementation on tumour proliferation. A metabolic control analysis study.

    Begoña Comín-Anduix;Joan Boren;Sonia Martinez;Cristina Moro

  • Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells.

    Joan Boren;Marta Cascante;Silvia Marin;Begoña Comı́n-Anduix

  • Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway

    Fernando J. Reyes-Zurita;Eva E. Rufino-Palomares;José A. Lupiáñez;Marta Cascante

  • Relationships between inhibition constants, inhibitor concentrations for 50% inhibition and types of inhibition: new ways of analysing data.

    Antoni Cortés;Marta Cascante;María Luz Cárdenas;Athel Cornish-Bowden

  • From correlation to causation: analysis of metabolomics data using systems biology approaches

    Antonio Rosato;Leonardo Tenori;Marta Cascante;Pedro Ramon De Atauri Carulla

  • Metabolic profiling of cell growth and death in cancer: applications in drug discovery.

    László G Boros;Marta Cascante;Wai Nang Paul Lee

  • Reactive Oxygen Species Production by Forward and Reverse Electron Fluxes in the Mitochondrial Respiratory Chain

    Vitaly A. Selivanov;Tatyana V. Votyakova;Violetta N. Pivtoraiko;Jennifer Zeak

  • Metabolic strategy of boar spermatozoa revealed by a metabolomic characterization

    Silvia Marin;Kelly Chiang;Sara Bassilian;Wai Nang Paul Lee

  • Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for “Precision Medicine and Pharmacometabolomics Task Group”—The Metabolomics Society Initiative)

    Jennifer A Kirwan;Lorraine Brennan;David Broadhurst;Oliver Fiehn

Frequent Co-Authors

Josep Roca
Josep Roca University of Barcelona
Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Boris N. Kholodenko
Boris N. Kholodenko University College Dublin
Enric I. Canela
Enric I. Canela University of Barcelona
Reza M. Salek
Reza M. Salek International Agency For Research On Cancer
Rafael Franco
Rafael Franco University of Barcelona
Mercè Font-Bardia
Mercè Font-Bardia University of Barcelona
Christoph Steinbeck
Christoph Steinbeck Friedrich Schiller University Jena
Francesco Falciani
Francesco Falciani University of Liverpool
Thomas Hankemeier
Thomas Hankemeier Leiden University

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