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Biology and Biochemistry

D-Index
50
Citations
12278
World Ranking
17484
National Ranking
23

Overview

Jacky L. Snoep is affiliated with Stellenbosch University in South Africa with a research focus spanning biochemistry, genetics, and molecular biology as well as medicine. Their body of work primarily addresses molecular biology, endocrinology, diabetes and metabolism, public health, environmental and occupational health, cell biology, and plant science.

The main research topics covered in their publications include:

  • Hormonal and reproductive studies
  • Hormonal regulation and hypertension
  • Microbial metabolic engineering and bioproduction
  • Gene regulatory network analysis
  • Aldose reductase and taurine
  • Sexual differentiation and disorders
  • Bioinformatics and genomic networks

Frequent coauthors collaborating with Snoep are:

  • David D. van Niekerk
  • Bettina Siebers
  • Christopher Bräsen
  • Wiebke Arlt
  • Karl-Heinz Storbeck

They have published regularly in certain venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • The Journal of Steroid Biochemistry and Molecular Biology
  • Journal of Biological Chemistry
  • Biosystems

Some notable recent papers include:

  • "A combined experimental and modelling approach for the Weimberg pathway optimisation," 2020, Nature Communications
  • "BioSimulators: a central registry of simulation engines and services for recommending specific tools," 2022, CU Scholar (University of Colorado Boulder)
  • "The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1," 2020, The Journal of Steroid Biochemistry and Molecular Biology
  • "Intercellular communication induces glycolytic synchronization waves between individually oscillating cells," 2021, Proceedings of the National Academy of Sciences
  • "Workflows for optimization of enzyme cascades and whole cell catalysis based on enzyme kinetic characterization and pathway modelling," 2021, Current Opinion in Biotechnology

Jacky L. Snoep's research contributions intersect fundamental biochemistry with applied approaches in hormonal regulation, metabolic engineering, and enzyme kinetics. Their interdisciplinary work engages both experimental and modelling methodologies to address biological pathways and regulatory mechanisms.

Best Publications

  • The Systems Biology Graphical Notation

    Nicolas Le Novere;Michael Hucka;Huaiyu Mi;Stuart Moodie

  • BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems

    Nicolas Le Novère;Benjamin J. Bornstein;Alexander Broicher;Mélanie Courtot

  • Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry.

    Bas Teusink;Jutta Passarge;Corinne A. Reijenga;Eugenia Esgalhado

  • Minimum information requested in the annotation of biochemical models (MIRIAM)

    Nicolas Le Novère;Andrew Finney;Michael Hucka;Upinder S. Bhalla

  • Biomodels database: an enhanced curated and annotated resource for published quantitative kinetic models

    Chen Li;Marco Donizelli;Nicolas Rodriguez;Harish Dharuri

  • The Steady-State Internal Redox State (NADH/NAD) Reflects the External Redox State and Is Correlated with Catabolic Adaptation in Escherichia coli

    M.R. de Graef;S.V. Alexeeva;J.L. Snoep;M.J. Teixeira De Mattos

  • Web-based kinetic modelling using JWS Online

    Brett G. Olivier;Jacky L. Snoep

  • The glycolytic flux in Escherichia coli is controlled by the demand for ATP.

    Brian J. Koebmann;Hans V. Westerhoff;Jacky L. Snoep;Dan Nilsson

  • Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis

    Marcel H. N. Hoefnagel;Marjo J. C. Starrenburg;Dirk E. Martens;Jeroen Hugenholtz

  • Reproducible computational biology experiments with SED-ML--the Simulation Experiment Description Markup Language.

    Dagmar Waltemath;Richard R. Adams;Frank T. Bergmann;Michael Hucka

  • Minimum Information About a Simulation Experiment (MIASE)

    Dagmar Waltemath;Richard R. Adams;Daniel A. Beard;Frank T. Bergmann;Frank T. Bergmann

  • Isolation, characterization, and physiological role of the pyruvate dehydrogenase complex and alpha-acetolactate synthase of Lactococcus lactis subsp. lactis bv. diacetylactis.

    J. L. Snoep;M. J. Teixeira De Mattos;M. J. C. Starrenburg;J. Hugenholtz

  • Construction and Characterization of an Effector Strain of Streptococcus mutans for Replacement Therapy of Dental Caries

    J. D. Hillman;T. A. Brooks;S. M. Michalek;C. C. Harmon

  • Towards building the silicon cell: a modular approach.

    Jacky L. Snoep;Frank Bruggeman;Brett G. Olivier;Hans V. Westerhoff;Hans V. Westerhoff

  • Transduction of Intracellular and Intercellular Dynamics in Yeast Glycolytic Oscillations

    Jana Wolf;Jutta Passarge;Oscar J.G. Somsen;Jacky L. Snoep

  • Protein burden in Zymomonas mobilis: negative flux and growth control due to overproduction of glycolytic enzymes

    Jacky L. Snoep;Lorraine P. Yomano;Hans V. Westerhoff;Lonnie O. Ingram

  • DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase.

    Jacky L. Snoep;Jacky L. Snoep;Coen C. van der Weijden;Heidi W. Andersen;Heidi W. Andersen;Hans V. Westerhoff;Hans V. Westerhoff

  • Role of hexose transport in control of glycolytic flux in Saccharomyces cerevisiae.

    Karin Elbing;Christer Larsson;Roslyn M. Bill;Eva Albers

  • Characterization of the Zymomonas mobilis glucose facilitator gene product (glf) in recombinant Escherichia coli: examination of transport mechanism, kinetics and the role of glucokinase in glucose transport

    Corrine Parker;Wendy O. Barnell;Jacky L. Snoep;Lonnie O. Ingram

  • Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes

    Teusink B;Passarge J;Reijenga Ka;Esgalhado E

Frequent Co-Authors

Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Carole Goble
Carole Goble University of Manchester
Peter Ruhdal Jensen
Peter Ruhdal Jensen Technical University of Denmark
Barbara M. Bakker
Barbara M. Bakker University Medical Center Groningen
Boris N. Kholodenko
Boris N. Kholodenko University College Dublin
Nicolas Le Novère
Nicolas Le Novère Babraham Institute
Michael Hucka
Michael Hucka California Institute of Technology
Bas Teusink
Bas Teusink Vrije Universiteit Amsterdam
Henning Hermjakob
Henning Hermjakob European Bioinformatics Institute
Herbert M. Sauro
Herbert M. Sauro University of Washington

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