Her main research concerns Biochemistry, Glycolysis, Trypanosoma brucei, Glycosome and Saccharomyces cerevisiae. Her work is connected to Enzyme, Glycerol phosphate shuttle, Mitochondrion, NADH dehydrogenase and Glycerol-3-phosphate dehydrogenase, as a part of Biochemistry. Her Glycolysis research includes elements of Dihydroxyacetone phosphate, Extracellular, Glycerol, Triosephosphate isomerase and Allosteric regulation.
Her Trypanosoma brucei study incorporates themes from Glyceraldehyde 3-phosphate dehydrogenase, Phosphoglycerate kinase, Hexokinase, Flux and Aldolase A. Her Glycosome research is multidisciplinary, relying on both Glucose 6-phosphate, Cell biology and Cell Compartmentation. Her Saccharomyces cerevisiae study is related to the wider topic of Yeast.
Her primary areas of investigation include Biochemistry, Glycolysis, Systems biology, Saccharomyces cerevisiae and Computational biology. Her study in Trypanosoma brucei, Enzyme, Yeast, Flux and Cytosol falls within the category of Biochemistry. Her Trypanosoma brucei research is multidisciplinary, incorporating elements of Glyceraldehyde 3-phosphate dehydrogenase and Phosphoglycerate kinase.
Barbara M. Bakker combines subjects such as Extracellular, Cell biology and Allosteric regulation with her study of Glycolysis. Her work in Systems biology addresses issues such as Biological system, which are connected to fields such as Enzyme kinetics and Gene regulatory network. Her Saccharomyces cerevisiae research integrates issues from Biophysics, Regulation of gene expression and Metabolism.
Her primary scientific interests are in Internal medicine, Endocrinology, Cell biology, Cancer research and Glycolysis. Her work on High plasma, Lipolysis and Cholesterol as part of general Internal medicine research is frequently linked to Metabolic syndrome and Increased VLDL, bridging the gap between disciplines. The concepts of her Endocrinology study are interwoven with issues in Tryptophan, Nicotinamide and Liver dysfunction.
Her research integrates issues of Flux and Pyruvate dehydrogenase complex in her study of Cell biology. In her work, Hepatic stellate cell is strongly intertwined with Oxidative phosphorylation, which is a subfield of Glycolysis. Her Respiratory system study combines topics from a wide range of disciplines, such as Transcriptome, Biochemistry and Skeletal muscle.
Barbara M. Bakker mainly investigates Cell biology, Biochemistry, Pyruvate dehydrogenase complex, Flux and Citric acid cycle. As part of her studies on Cell biology, she frequently links adjacent subjects like Fatty acid synthesis. Barbara M. Bakker interconnects Sarcopenia, Proteome, Transcriptome, Endurance training and Respiratory system in the investigation of issues within Pyruvate dehydrogenase complex.
Her biological study spans a wide range of topics, including Glycolysis, Oxidative phosphorylation, Neurodegeneration and Skeletal muscle. The Citric acid cycle study combines topics in areas such as Cancer cell, Adenosine triphosphate, Cytosol, Glutamine and Excretion. Her Cell growth research extends to Excretion, which is thematically connected.
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The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
Gijs Den Besten;Karen Van Eunen;Albert K. Groen;Koen Venema.
Journal of Lipid Research (2013)
Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry.
Bas Teusink;Jutta Passarge;Corinne A. Reijenga;Eugenia Esgalhado.
FEBS Journal (2000)
Short-Chain Fatty Acids protect against High-Fat Diet-Induced Obesity via a PPARγ-dependent switch from lipogenesis to fat oxidation
Gijs den Besten;Aycha Bleeker;Albert Gerding;Karen van Eunen.
Diabetes (2015)
Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae
Barbara M. Bakker;Karin M. Overkamp;Antonius J.A. van Maris;Peter Kötter.
Fems Microbiology Reviews (2001)
Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids
Gijs den Besten;Katja Lange;Rick Havinga;Theo H van Dijk.
American Journal of Physiology-gastrointestinal and Liver Physiology (2013)
Glycolysis in Bloodstream Form Trypanosoma brucei Can Be Understood in Terms of the Kinetics of the Glycolytic Enzymes
Barbara M. Bakker;Barbara M. Bakker;Paul A.M. Michels;Fred R. Opperdoes;Hans V. Westerhoff.
Journal of Biological Chemistry (1997)
The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels.
Pascale Daran-Lapujade;Sergio Rossell;Walter M. van Gulik;Marijke A. H. Luttik.
Proceedings of the National Academy of Sciences of the United States of America (2007)
What Controls Glycolysis in Bloodstream Form Trypanosoma brucei
Barbara M. Bakker;Barbara M. Bakker;Paul A.M. Michels;Fred R. Opperdoes;Hans V. Westerhoff;Hans V. Westerhoff.
Journal of Biological Chemistry (1999)
Acetaldehyde mediates the synchronization of sustained glycolytic oscillations in populations of yeast cells
P. Richard;B.M. Bakker;B. Teusink;K. van Dam.
FEBS Journal (1996)
Compartmentation protects trypanosomes from the dangerous design of glycolysis
BM Bakker;Fic Mensonides;B Teusink;P van Hoek.
Proceedings of the National Academy of Sciences of the United States of America (2000)
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