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Biology and Biochemistry

D-Index
55
Citations
16881
World Ranking
14796
National Ranking
360

Overview

Barbara M. Bakker is affiliated with the University Medical Center Groningen in the Netherlands. Their research spans a diverse range of topics primarily within biochemistry, genetics, molecular biology, and medicine. They have contributed substantially to the understanding of metabolism, molecular biology, physiology, and clinical biochemistry, with notable work extending into cancer research and surgery.

The main fields of study associated with Bakker include Biochemistry, Genetics and Molecular Biology with 93 publications, and Medicine with 81 publications. More specific subfields of study comprise Molecular Biology (51 publications), Physiology (31 publications), Clinical Biochemistry (15 publications), Cancer Research (9 publications), and Surgery (9 publications).

Bakker's research interests cover several key topics:

  • Diet and metabolism studies
  • Metabolism and Genetic Disorders
  • Adipose Tissue and Metabolism
  • Cancer, Hypoxia, and Metabolism
  • Mitochondrial Function and Pathology
  • Metabolism, Diabetes, and Cancer
  • Metabolomics and Mass Spectrometry Studies

Their recent papers include:

  • Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction (2023) Nature Communications
  • Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis (2020) Proceedings of the National Academy of Sciences
  • Short-Chain Fatty Acids in the Metabolism of Heart Failure - Rethinking the Fat Stigma (2022) Frontiers in Cardiovascular Medicine
  • Simultaneous Induction of Glycolysis and Oxidative Phosphorylation during Activation of Hepatic Stellate Cells Reveals Novel Mitochondrial Targets to Treat Liver Fibrosis (2020) Cells
  • SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans (2020) Cell Death and Disease

Bakker frequently collaborates with other researchers. Frequent co-authors include Albert Gerding, Justina C. Wolters, Marcel A. Vieira-Lara, Dirk-Jan Reijngoud, and Karen van Eunen.

Common publication venues for Bakker's work are:

  • bioRxiv (Cold Spring Harbor Laboratory) with 9 publications
  • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease with 4 publications
  • University of Groningen research database (University of Groningen / Centre for Information Technology) with 4 publications
  • Nature Communications with 3 publications
  • Scientific Reports with 3 publications

Best Publications

  • The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

    Gijs Den Besten;Karen Van Eunen;Albert K. Groen;Koen Venema

  • Short-Chain Fatty Acids protect against High-Fat Diet-Induced Obesity via a PPARγ-dependent switch from lipogenesis to fat oxidation

    Gijs den Besten;Aycha Bleeker;Albert Gerding;Karen van Eunen

  • Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry.

    Bas Teusink;Jutta Passarge;Corinne A. Reijenga;Eugenia Esgalhado

  • Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae

    Barbara M. Bakker;Karin M. Overkamp;Antonius J.A. van Maris;Peter Kötter

  • Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids

    Gijs den Besten;Katja Lange;Rick Havinga;Theo H van Dijk

  • A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis.

    Eelke Brandsma;Niels J. Kloosterhuis;Mirjam Koster;Mirjam Koster;Daphne C. Dekker

  • Glycolysis in Bloodstream Form Trypanosoma brucei Can Be Understood in Terms of the Kinetics of the Glycolytic Enzymes

    Barbara M. Bakker;Barbara M. Bakker;Paul A.M. Michels;Fred R. Opperdoes;Hans V. Westerhoff

  • The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels.

    Pascale Daran-Lapujade;Sergio Rossell;Walter M. van Gulik;Marijke A. H. Luttik

  • Acetaldehyde mediates the synchronization of sustained glycolytic oscillations in populations of yeast cells

    P. Richard;B.M. Bakker;B. Teusink;K. van Dam

  • What Controls Glycolysis in Bloodstream Form Trypanosoma brucei

    Barbara M. Bakker;Barbara M. Bakker;Paul A.M. Michels;Fred R. Opperdoes;Hans V. Westerhoff;Hans V. Westerhoff

  • Compartmentation protects trypanosomes from the dangerous design of glycolysis

    BM Bakker;Fic Mensonides;B Teusink;P van Hoek

  • Experimental and in Silico Analyses of Glycolytic Flux Control in Bloodstream Form Trypanosoma brucei

    Marie Astrid Albert;Jurgen R. Haanstra;Véronique Hannaert;Joris Van Roy

  • Roles of triosephosphate isomerase and aerobic metabolism in Trypanosoma brucei.

    Sandra Helfert;Antonio M. Estévez;Barbara Bakker;Barbara Bakker;Paul Michels

  • The Mitochondrial Alcohol Dehydrogenase Adh3p Is Involved in a Redox Shuttle in Saccharomyces cerevisiae

    Barbara M. Bakker;Christoffer Bro;Christoffer Bro;Peter Kötter;Marijke A. H. Luttik

  • Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes.

    Jurgen R. Haanstra;Arjen van Tuijl;Peter Kessler;Willem Reijnders

  • Measuring enzyme activities under standardized in vivo-like conditions for Systems Biology

    Karen van Eunen;Jildau Bouwman;Pascale Daran-Lapujade;Jarne Postmus

  • In vivo analysis of the mechanisms for oxidation of cytosolic NADH by Saccharomyces cerevisiae mitochondria

    K.M. Overkamp;B.M. Bakker;P. Kotter;A. van Tuijl

  • How yeast cells synchronize their glycolytic oscillations: a perturbation analytic treatment.

    Martin Bier;Barbara M. Bakker;Hans V. Westerhoff

  • Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction

    Tim van Zutphen;Jolita Ciapaite;Jolita Ciapaite;Vincent W. Bloks;Cameron Ackereley

  • Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes

    Teusink B;Passarge J;Reijenga Ka;Esgalhado E

Frequent Co-Authors

Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Jacky L. Snoep
Jacky L. Snoep Stellenbosch University
Paul A. M. Michels
Paul A. M. Michels University of Edinburgh
Bas Teusink
Bas Teusink Vrije Universiteit Amsterdam
Albert K. Groen
Albert K. Groen University of Amsterdam
Jack T. Pronk
Jack T. Pronk Delft University of Technology
Rainer Breitling
Rainer Breitling University of Manchester
Michael P. Barrett
Michael P. Barrett University of Glasgow
Christine Clayton
Christine Clayton Heidelberg University
Fred R. Opperdoes
Fred R. Opperdoes Université Catholique de Louvain

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