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Biology and Biochemistry
Belgium
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
18004
World Ranking
4864
National Ranking
76

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Belgium Leader Award

Overview

Fred R. Opperdoes is affiliated with Université Catholique de Louvain in Belgium and specializes in research at the intersection of medicine, biochemistry, genetics, and molecular biology. Their work focuses primarily on protozoan parasites, especially Trypanosoma species and Leishmaniasis, with additional interests in protist diversity, parasite-host interactions, and genomics.

The main fields of study associated with their research include Medicine and Biochemistry, Genetics and Molecular Biology. More specific subfields include Molecular Biology, Epidemiology, Public Health, Environmental and Occupational Health, Parasitology, and Plant Science.

Research topics prominently explored by Opperdoes cover:

  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Protist diversity and phylogeny
  • Parasites and Host Interactions
  • Genomics and Phylogenetic Studies
  • Toxoplasma gondii Research Studies
  • Venomous Animal Envenomation and Studies

Several recent papers provide insight into the scientist's research contributions:

  • "Evolution of metabolic capabilities and molecular features of diplonemids, kinetoplastids, and euglenids" (2020), published in BMC Biology
  • "Genome Analysis of Endotrypanum and Porcisia spp., Closest Phylogenetic Relatives of Leishmania, Highlights the Role of Amastins in Shaping Pathogenicity" (2021), published in Genes
  • "The Remarkable Metabolism of Vickermania ingenoplastis: Genomic Predictions" (2021), published in Pathogens
  • "A New Model Trypanosomatid, Novymonas esmeraldas: Genomic Perception of Its "Candidatus Pandoraea novymonadis" Endosymbiont" (2021), published in mBio
  • "Leishmania guyanensis M4147 as a new LRV1-bearing model parasite: Phosphatidate phosphatase 2-like protein controls cell cycle progression and intracellular lipid content" (2022), published in PLoS Neglected Tropical Diseases

Frequent publication venues for Opperdoes include BMC Biology, Genes, Pathogens, mBio, and Nucleic Acids Research, indicating a broad engagement across molecular biology and parasitology-related journals.

The scientist has collaborated frequently with several co-authors in their research efforts, including:

  • Julius Lukeš
  • Vyacheslav Yurchenko
  • Anzhelika Butenko
  • Evgeny S. Gerasimov
  • Ingrid Škodová-Sveráková

Best Publications

  • The Genome of the African Trypanosome Trypanosoma brucei

    Matthew Berriman;Elodie Ghedin;Elodie Ghedin;Christiane Hertz-Fowler;Gaelle Blandin

  • Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei: the glycosome.

    Fred R. Opperdoes;Piet Borst

  • Glycolysis as a target for the design of new anti-trypanosome drugs

    Christophe L.M.J. Verlinde;Véronique Hannaert;Casimir Blonski;Michèle Willson

  • Glycolysis in Bloodstream Form Trypanosoma brucei Can Be Understood in Terms of the Kinetics of the Glycolytic Enzymes

    Barbara M. Bakker;Barbara M. Bakker;Paul A.M. Michels;Fred R. Opperdoes;Hans V. Westerhoff

  • Plant-like traits associated with metabolism of Trypanosoma parasites.

    Véronique Hannaert;Emma Saavedra;Francis Duffieux;Jean-Pierre Szikora

  • Glycolytic enzymes of Trypanosoma brucei. Simultaneous purification, intraglycosomal concentrations and physical properties.

    Onno Misset;Octaaf J. M. Bos;Fred R. Opperdoes

  • What Controls Glycolysis in Bloodstream Form Trypanosoma brucei

    Barbara M. Bakker;Barbara M. Bakker;Paul A.M. Michels;Fred R. Opperdoes;Hans V. Westerhoff;Hans V. Westerhoff

  • Metabolism of Leishmania : proven and predicted

    Frederik Opperdoes;Graham H Coombs

  • Ether--lipid (alkyl-phospholipid) metabolism and the mechanism of action of ether--lipid analogues in Leishmania.

    Henning Lux;Norton Heise;Thomas Klenner;David Hart

  • Receptors for the host low density lipoproteins on the hemoflagellate Trypanosoma brucei: purification and involvement in the growth of the parasite

    I. Coppens;Pierre Baudhuin;Frederik Opperdoes;Pierre J. Courtoy

  • Experimental and in Silico Analyses of Glycolytic Flux Control in Bloodstream Form Trypanosoma brucei

    Marie Astrid Albert;Jurgen R. Haanstra;Véronique Hannaert;Joris Van Roy

  • Subcellular Fractionation of Trypanosoma brucei Bloodstream Forms with Special Reference to Hydrolases

    Rolf F. Steiger;Fred R. Opperdoes;José Bontemps

  • Trypanosomatidae produce acetate via a mitochondrial acetate:succinate CoA transferase

    J J Van Hellemond;Frederik Opperdoes;A G Tielens

  • The occurrence of glycosomes (microbodies) in the promastigote stage of four major Leishmania species.

    David T. Hart;Fred R. Opperdoes

  • Glycolysis in Trypanosoma brucei

    Nico Visser;Fred R. Opperdoes

  • Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase

    A. M. Aronov;S. Suresh;F. S. Buckner;W. C. Van Voorhis

  • Simultaneous purification of hexokinase, class‐I fructose‐bisphosphate aldolase, triosephosphate isomerase and phosphoglycerate kinase from Trypanosoma brucei

    Onno Misset;Fred R. Opperdoes

  • Characterization of the ysa Pathogenicity Locus in the Chromosome of Yersinia enterocolitica and Phylogeny Analysis of Type III Secretion Systems

    Boris Foultier;Paul Troisfontaines;Simone Müller;Fred R. Opperdoes

  • Localization of glycerol-3-phosphate oxidase in the mitochondrion and particulate NAD+-linked glycerol-3-phosphate dehydrogenase in the microbodies of the bloodstream form to Trypanosoma brucei.

    Fred R. Opperdoes;Piet Borst;Suzanne Bakker;Wolter Leene

  • Carbohydrate metabolism in African trypanosomes, with special reference to the glycosome.

    Alan H. Fairlamb;Fred R. Opperdoes

Frequent Co-Authors

Paul A. M. Michels
Paul A. M. Michels University of Edinburgh
Julius Lukeš
Julius Lukeš Czech Academy of Sciences
Vyacheslav Yurchenko
Vyacheslav Yurchenko University of Ostrava
Rik K. Wierenga
Rik K. Wierenga University of Oulu
Wim G. J. Hol
Wim G. J. Hol University of Washington
Emile Van Schaftingen
Emile Van Schaftingen Université Catholique de Louvain
Barbara M. Bakker
Barbara M. Bakker University Medical Center Groningen
Daniel J. Rigden
Daniel J. Rigden University of Liverpool
Alan H. Fairlamb
Alan H. Fairlamb University of Dundee
Aloysius G.M. Tielens
Aloysius G.M. Tielens Erasmus University Rotterdam

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