2013 - Fellow of the Royal Society of Edinburgh
Michael P. Barrett focuses on Biochemistry, Trypanosoma brucei, African trypanosomiasis, Pharmacology and Metabolomics. His study connects Leishmania and Biochemistry. His Trypanosoma brucei research incorporates elements of Nucleoside transporter, Transporter, Virology, Purine and Trypanosoma cruzi.
Fexinidazole is closely connected to Drug development in his research, which is encompassed under the umbrella topic of African trypanosomiasis. His Pharmacology research focuses on Drug resistance and how it connects with Leishmania donovani. His work deals with themes such as Metabolite, Computational biology, Data mining and Mass spectrometry, which intersect with Metabolomics.
The scientist’s investigation covers issues in Biochemistry, Trypanosoma brucei, African trypanosomiasis, Metabolomics and Pharmacology. Michael P. Barrett regularly links together related areas like Molecular biology in his Biochemistry studies. His research investigates the connection between Trypanosoma brucei and topics such as Virology that intersect with problems in Drug resistance.
His biological study spans a wide range of topics, including Nifurtimox and Eflornithine. His Metabolomics research includes elements of Metabolite, Computational biology and Mass spectrometry. Michael P. Barrett is interested in Drug, which is a branch of Pharmacology.
His main research concerns Trypanosoma brucei, Metabolomics, Biochemistry, African trypanosomiasis and Pharmacology. Michael P. Barrett interconnects Glycolysis, Polyadenylation, Oxidative phosphorylation, Trypanosoma and Cell biology in the investigation of issues within Trypanosoma brucei. His Metabolomics study combines topics in areas such as Metabolite, Computational biology, Virulence and Leishmania.
In his study, Leishmaniasis is inextricably linked to Drug discovery, which falls within the broad field of Computational biology. African trypanosomiasis is a subfield of Trypanosomiasis that Michael P. Barrett tackles. His research investigates the connection between Pharmacology and topics such as In vivo that intersect with issues in Proteasome, Drug repositioning and Virology.
His primary areas of investigation include African trypanosomiasis, Metabolomics, Biochemistry, Drug resistance and Trypanosoma brucei. His work carried out in the field of African trypanosomiasis brings together such families of science as Disease and Intensive care medicine. His Metabolomics research is multidisciplinary, incorporating elements of Metabolite and Computational biology.
Many of his studies on Biochemistry apply to Leishmania as well. The various areas that he examines in his Drug resistance study include Miltefosine, Antibiotic resistance, Sterol and Leishmania mexicana. His biological study spans a wide range of topics, including Structure–activity relationship, Transcription and Trypanosoma.
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Chemotherapy of trypanosomiases and leishmaniasis
Simon L. Croft;Michael P. Barrett;Julio A. Urbina.
Trends in Parasitology (2005)
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease
M P Barrett;D W Boykin;R Brun;R R Tidwell.
British Journal of Pharmacology (2007)
Drug resistance and treatment failure in leishmaniasis: A 21st century challenge
Alicia Ponte-Sucre;Francisco Gamarro;Jean-Claude Dujardin;Michael P. Barrett.
PLOS Neglected Tropical Diseases (2017)
Toward global metabolomics analysis with hydrophilic interaction liquid chromatography-mass spectrometry: improved metabolite identification by retention time prediction.
Darren J. Creek;Darren J. Creek;Andris Jankevics;Rainer Breitling;David G. Watson.
Analytical Chemistry (2011)
Management of trypanosomiasis and leishmaniasis
Michael P. Barrett;Simon L. Croft.
British Medical Bulletin (2012)
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future
Patrick G. Bray;Michael P. Barrett;Stephen A. Ward;Harry P. de Koning.
Trends in Parasitology (2003)
IDEOM : an Excel interface for analysis of LC-MS-based metabolomics data
Darren J. Creek;Darren J. Creek;Andris Jankevics;Karl E. V. Burgess;Rainer Breitling.
Separation of parasites from human blood using deterministic lateral displacement
Stefan H. Holm;Jason P. Beech;Michael P. Barrett;Jonas O. Tegenfeldt;Jonas O. Tegenfeldt.
Lab on a Chip (2011)
Proline metabolism in procyclic Trypanosoma brucei is down-regulated in the presence of glucose.
Nadia Lamour;Loïc Rivière;Virginie Coustou;Graham H. Coombs.
Journal of Biological Chemistry (2005)
Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites.
Alessandro Baliani;Gorka Jimenez Bueno;Mhairi L. Stewart;Vanessa Yardley.
Journal of Medicinal Chemistry (2005)
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