H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 13,200 218 World Ranking 4047 National Ranking 322

Research.com Recognitions

Awards & Achievements

2013 - Fellow of the Royal Society of Edinburgh

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

Michael P. Barrett focuses on Biochemistry, Trypanosoma brucei, African trypanosomiasis, Pharmacology and Metabolomics. His study connects Leishmania and Biochemistry. His Trypanosoma brucei research incorporates elements of Nucleoside transporter, Transporter, Virology, Purine and Trypanosoma cruzi.

Fexinidazole is closely connected to Drug development in his research, which is encompassed under the umbrella topic of African trypanosomiasis. His Pharmacology research focuses on Drug resistance and how it connects with Leishmania donovani. His work deals with themes such as Metabolite, Computational biology, Data mining and Mass spectrometry, which intersect with Metabolomics.

His most cited work include:

  • Chemotherapy of trypanosomiases and leishmaniasis (322 citations)
  • Drug resistance and treatment failure in leishmaniasis: A 21st century challenge (259 citations)
  • Human African trypanosomiasis: pharmacological re-engagement with a neglected disease (258 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Biochemistry, Trypanosoma brucei, African trypanosomiasis, Metabolomics and Pharmacology. Michael P. Barrett regularly links together related areas like Molecular biology in his Biochemistry studies. His research investigates the connection between Trypanosoma brucei and topics such as Virology that intersect with problems in Drug resistance.

His biological study spans a wide range of topics, including Nifurtimox and Eflornithine. His Metabolomics research includes elements of Metabolite, Computational biology and Mass spectrometry. Michael P. Barrett is interested in Drug, which is a branch of Pharmacology.

He most often published in these fields:

  • Biochemistry (33.81%)
  • Trypanosoma brucei (31.53%)
  • African trypanosomiasis (15.06%)

What were the highlights of his more recent work (between 2015-2021)?

  • Trypanosoma brucei (31.53%)
  • Metabolomics (12.50%)
  • Biochemistry (33.81%)

In recent papers he was focusing on the following fields of study:

His main research concerns Trypanosoma brucei, Metabolomics, Biochemistry, African trypanosomiasis and Pharmacology. Michael P. Barrett interconnects Glycolysis, Polyadenylation, Oxidative phosphorylation, Trypanosoma and Cell biology in the investigation of issues within Trypanosoma brucei. His Metabolomics study combines topics in areas such as Metabolite, Computational biology, Virulence and Leishmania.

In his study, Leishmaniasis is inextricably linked to Drug discovery, which falls within the broad field of Computational biology. African trypanosomiasis is a subfield of Trypanosomiasis that Michael P. Barrett tackles. His research investigates the connection between Pharmacology and topics such as In vivo that intersect with issues in Proteasome, Drug repositioning and Virology.

Between 2015 and 2021, his most popular works were:

  • Drug resistance and treatment failure in leishmaniasis: A 21st century challenge (259 citations)
  • The animal trypanosomiases and their chemotherapy: a review. (135 citations)
  • Topic modeling for untargeted substructure exploration in metabolomics (114 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

His primary areas of investigation include African trypanosomiasis, Metabolomics, Biochemistry, Drug resistance and Trypanosoma brucei. His work carried out in the field of African trypanosomiasis brings together such families of science as Disease and Intensive care medicine. His Metabolomics research is multidisciplinary, incorporating elements of Metabolite and Computational biology.

Many of his studies on Biochemistry apply to Leishmania as well. The various areas that he examines in his Drug resistance study include Miltefosine, Antibiotic resistance, Sterol and Leishmania mexicana. His biological study spans a wide range of topics, including Structure–activity relationship, Transcription and Trypanosoma.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Chemotherapy of trypanosomiases and leishmaniasis

Simon L. Croft;Michael P. Barrett;Julio A. Urbina.
Trends in Parasitology (2005)

489 Citations

Human African trypanosomiasis: pharmacological re-engagement with a neglected disease

M P Barrett;D W Boykin;R Brun;R R Tidwell.
British Journal of Pharmacology (2007)

390 Citations

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

Alicia Ponte-Sucre;Francisco Gamarro;Jean-Claude Dujardin;Michael P. Barrett.
PLOS Neglected Tropical Diseases (2017)

328 Citations

Toward global metabolomics analysis with hydrophilic interaction liquid chromatography-mass spectrometry: improved metabolite identification by retention time prediction.

Darren J. Creek;Darren J. Creek;Andris Jankevics;Rainer Breitling;David G. Watson.
Analytical Chemistry (2011)

317 Citations

Management of trypanosomiasis and leishmaniasis

Michael P. Barrett;Simon L. Croft.
British Medical Bulletin (2012)

306 Citations

Pentamidine uptake and resistance in pathogenic protozoa: past, present and future

Patrick G. Bray;Michael P. Barrett;Stephen A. Ward;Harry P. de Koning.
Trends in Parasitology (2003)

266 Citations

IDEOM : an Excel interface for analysis of LC-MS-based metabolomics data

Darren J. Creek;Darren J. Creek;Andris Jankevics;Karl E. V. Burgess;Rainer Breitling.
Bioinformatics (2012)

263 Citations

Separation of parasites from human blood using deterministic lateral displacement

Stefan H. Holm;Jason P. Beech;Michael P. Barrett;Jonas O. Tegenfeldt;Jonas O. Tegenfeldt.
Lab on a Chip (2011)

224 Citations

Proline metabolism in procyclic Trypanosoma brucei is down-regulated in the presence of glucose.

Nadia Lamour;Loïc Rivière;Virginie Coustou;Graham H. Coombs.
Journal of Biological Chemistry (2005)

215 Citations

Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites.

Alessandro Baliani;Gorka Jimenez Bueno;Mhairi L. Stewart;Vanessa Yardley.
Journal of Medicinal Chemistry (2005)

207 Citations

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Best Scientists Citing Michael P. Barrett

Reto Brun

Reto Brun

Swiss Tropical and Public Health Institute

Publications: 96

Harry P. de Koning

Harry P. de Koning

University of Glasgow

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Marcel Kaiser

Marcel Kaiser

Swiss Tropical and Public Health Institute

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Julius Lukeš

Julius Lukeš

Czech Academy of Sciences

Publications: 79

Paul A. M. Michels

Paul A. M. Michels

University of Edinburgh

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David W. Boykin

David W. Boykin

Georgia State University

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Pascal Mäser

Pascal Mäser

Swiss Tropical and Public Health Institute

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Frédéric Bringaud

Frédéric Bringaud

University of Bordeaux

Publications: 54

Alan H. Fairlamb

Alan H. Fairlamb

University of Dundee

Publications: 45

Malcolm J. McConville

Malcolm J. McConville

University of Melbourne

Publications: 43

David Horn

David Horn

University of Dundee

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Mark C. Field

Mark C. Field

University of Dundee

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Pieter C. Dorrestein

Pieter C. Dorrestein

University of California, San Diego

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John M. Kelly

John M. Kelly

University of London

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W. David Wilson

W. David Wilson

Georgia State University

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Richard R. Tidwell

Richard R. Tidwell

University of North Carolina at Chapel Hill

Publications: 35

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