World's Best Scientists 2026 revealed!
Christine Clayton

Christine Clayton

D-Index & Metrics

Molecular Biology

D-Index
76
Citations
17368
World Ranking
1162
National Ranking
90

Overview

Christine Clayton is affiliated with Heidelberg University in Germany and has contributed extensively to the field of Medicine, with a focus on Epidemiology, Molecular Biology, Immunology, Cardiology and Cardiovascular Medicine, as well as Public Health, Environmental and Occupational Health. Their research spans multiple subfields and addresses a range of biological and medical topics.

The scientist's main research topics include Trypanosoma species research and implications, Galectins and Cancer Biology, Cardiomyopathy and Myosin Studies, Biochemical and Molecular Research, Research on Leishmaniasis Studies, Plant Virus Research Studies, and RNA and protein synthesis mechanisms.

Christine Clayton has frequently published in several venues, with notable contributions in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Journal of Biological Chemistry
  • PLoS neglected tropical diseases
  • Parasitology

The scientist's published papers include:

  • "Functional insights from a surface antigen mRNA-bound proteome," 2021, eLife
  • "The RNA-associated proteins MKT1 and MKT1L form alternative PBP1-containing complexes in Trypanosoma brucei," 2020, Journal of Biological Chemistry
  • "In vitro culture of freshly isolated Trypanosoma brucei brucei bloodstream forms results in gene copy-number changes," 2021, PLoS neglected tropical diseases
  • "Insights into the functions and RNA binding of Trypanosoma brucei ZC3H22, RBP9 and DRBD7," 2021, Parasitology
  • "Distinct mRNA and protein interactomes highlight functional differentiation of major eIF4F-like complexes from Trypanosoma brucei," 2022, Frontiers in Molecular Biosciences

Collaboration has been a significant aspect of Christine Clayton's work. Frequent co-authors include:

  • Esteban Erben
  • Tania Bishola Tshitenge
  • Albina Waithaka
  • Larissa Mélo do Nascimento
  • Kevin Kamanyi Marucha

Best Publications

  • The genome of the kinetoplastid parasite, Leishmania major.

    Alasdair C. Ivens;Christopher S. Peacock;Elizabeth A. Worthey;Lee Murphy

  • Life without transcriptional control? From fly to man and back again

    Christine E. Clayton

  • Post-transcriptional regulation of gene expression in trypanosomes and leishmanias.

    Christine Clayton;Michal Shapira

  • Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

    S. Krieger;W. Schwarz;M. R. Ariyanayagam;A. H. Fairlamb

  • Inducible gene expression in trypanosomes mediated by a prokaryotic repressor.

    Elizabeth Wirtz;Christine Clayton

  • Vectors for inducible expression of toxic gene products in bloodstream and procyclic Trypanosoma brucei.

    S Biebinger;L E Wirtz;P Lorenz;C Clayton

  • The exosome of Trypanosoma brucei

    Antonio M. Estévez;Tore Kempf;Christine Clayton

  • The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei.

    J. C. B. M. Zomerdijk;M. Ouellette;A. L. M. A. ten Asbroek;R. Kieft

  • Regulation of gene expression in trypanosomatids: living with polycistronic transcription.

    Christine Clayton

  • Roles of triosephosphate isomerase and aerobic metabolism in Trypanosoma brucei.

    Sandra Helfert;Antonio M. Estévez;Barbara Bakker;Barbara Bakker;Paul Michels

  • Suppressor cells and loss of B-cell potential in mice infected with Trypanosoma brucei.

    A C Corsini;C Clayton;B A Askonas;B M Ogilvie

  • Gene expression in Kinetoplastids

    CE Clayton

  • A doubly inducible system for RNA interference and rapid RNAi plasmid construction in Trypanosoma brucei

    Vincent P. Alibu;Lilian Storm;Simon Haile;Christine Clayton

  • Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2α phosphorylation at Thr169

    Susanne Kramer;Rafael Queiroz;Louise Ellis;Helena Webb

  • The antioxidant systems in Toxoplasma gondii and the role of cytosolic catalase in defence against oxidative injury

    Martina Ding;Lai Yu Kwok;Lai Yu Kwok;Dirk Schlüter;Christine Clayton

  • Genetic manipulation of kinetoplastida.

    C.E Clayton

  • Mechanisms of developmental regulation in Trypanosoma brucei: a polypyrimidine tract in the 3'-untranslated region of a surface protein mRNA affects RNA abundance and translation.

    Hans-Rudolf Hotz;Claudia Hartmann;Karin Huober;Michael Hug

  • RNA-Binding Domain Proteins in Kinetoplastids: a Comparative Analysis

    Javier De Gaudenzi;Alberto C. Frasch;Christine Clayton

  • Transcription of the procyclic acidic repetitive protein genes of Trypanosoma brucei.

    C E Clayton;J P Fueri;J E Itzhaki;V Bellofatto

  • Compartmentation of enzymes in a microbody, the glycosome, is essential in Trypanosoma brucei.

    Cristina Guerra-Giraldez;Luis Quijada;Christine E. Clayton

Frequent Co-Authors

Jörg D. Hoheisel
Jörg D. Hoheisel German Cancer Research Center
Barbara M. Bakker
Barbara M. Bakker University Medical Center Groningen
Paul A. M. Michels
Paul A. M. Michels University of Edinburgh
Keith R. Matthews
Keith R. Matthews University of Edinburgh
Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Michael P. Barrett
Michael P. Barrett University of Glasgow
Mark Carrington
Mark Carrington University of Cambridge
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Kenneth Stuart
Kenneth Stuart University of Washington
Stephen M. Beverley
Stephen M. Beverley Washington University in St. Louis

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