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Molecular Biology

D-Index
65
Citations
16854
World Ranking
1663
National Ranking
130

Overview

Mark Carrington is affiliated with the University of Cambridge in the United Kingdom. Their research is mainly concentrated in the fields of epidemiology, public health, environmental and occupational health, molecular biology, immunology, and parasitology. These fields frame the context in which their scientific contributions have been made.

Their work covers several topics, including:

  • Trypanosoma species research and implications
  • Research on Leishmaniasis studies
  • Complement system in diseases
  • Vector-borne animal diseases
  • Viral infections and vectors
  • Vector-borne infectious diseases
  • Insect symbiosis and bacterial influences

Mark Carrington's recent publications illustrate their focus on trypanosome biology and host-pathogen interactions. Notable papers include:

  • "Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei," 2023, Nature Microbiology
  • "Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei," 2020, eLife
  • "A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies," 2020, Nature Communications
  • "Sequential production of gametes during meiosis in trypanosomes," 2021, Communications Biology
  • "Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor," 2022, Nature Communications

The venues where Mark Carrington frequently publishes include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Apollo (University of Cambridge)
  • Nature Microbiology

Collaboration is a significant aspect of their work. Frequent coauthors in their publications are:

  • Jack Daniel Sunter
  • Karen Billington
  • Clare Halliday
  • Ross Madden
  • Philip Dyer

Best Publications

  • The Genome of the African Trypanosome Trypanosoma brucei

    Matthew Berriman;Elodie Ghedin;Elodie Ghedin;Christiane Hertz-Fowler;Gaelle Blandin

  • The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Daniella C. Bartholomeu;Daniel Nilsson

  • TriTrypDB: a functional genomic resource for the Trypanosomatidae

    Martin Aslett;Cristina Aurrecoechea;Matthew Berriman;John Brestelli

  • Comparative genomics of trypanosomatid parasitic protozoa.

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Gaëlle Blandin;Matthew Berriman

  • Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero

    Michael Brandeis;Ian Rosewell;Mark Carrington;Tessa Crompton

  • The trypanosome flagellar pocket

    Mark C. Field;Mark Carrington

  • Conservation of the regulatory subunit for the Clp ATP-dependent protease in prokaryotes and eukaryotes.

    S Gottesman;C Squires;E Pichersky;M Carrington

  • Delayed early embryonic lethality following disruption of the murine cyclin A2 gene.

    Martin Murphy;Marie-Georges Stinnakre;Catherine Senamaud-Beaufort;Nicola J. Winston

  • A structural motif in the variant surface glycoproteins of Trypanosoma brucei

    Michael L. Blum;James A. Down;Anne M. Gurnett;Mark Carrington

  • GeneDB—an annotation database for pathogens

    Flora J. Logan-Klumpler;Nishadi De Silva;Ulrike Boehme;Matthew B Rogers

  • Identification of human-infective trypanosomes in animal reservoir of sleeping sickness in Uganda by means of serum-resistance-associated (SRA) gene.

    S.C. Welburn;K. Picozzi;Eric M. Fèvre;P.G. Coleman

  • A distinct cyclin A is expressed in germ cells in the mouse

    Claire Sweeney;Martin Murphy;Martin Murphy;Michal Kubelka;Michal Kubelka;Stuart E. Ravnik

  • Sleeping sickness in Uganda: a thin line between two fatal diseases

    Kim Picozzi;Eric M Fèvre;Martin Odiit;Mark Carrington

  • Functional genomics in Trypanosoma brucei: a collection of vectors for the expression of tagged proteins from endogenous and ectopic gene loci.

    Steven Kelly;Jenny Reed;Susanne Kramer;Louise Ellis

  • Expression of a polypeptide containing a dipeptide repeat is confined to the insect stage of Trypanosoma brucei

    Isabel Roditi;Mark Carrington;Mervyn Turner

  • Evolution of the primate trypanolytic factor APOL1

    Russell Thomson;Giulio Genovese;Chelsea Canon;Daniella Kovacsics;Daniella Kovacsics

  • Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2α phosphorylation at Thr169

    Susanne Kramer;Rafael Queiroz;Louise Ellis;Helena Webb

  • Variant specific glycoprotein of Trypanosoma brucei consists of two domains each having an independently conserved pattern of cysteine residues.

    Mark Carrington;Nancy Miller;Michael Blum;Isabel Roditi

  • Identification of the meiotic life cycle stage of Trypanosoma brucei in the tsetse fly

    Lori Peacock;Vanessa Ferris;Reuben Sharma;Jack Sunter

  • A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells

    Angela Schwede;Louise Ellis;Julia Luther;Mark Carrington

Frequent Co-Authors

Mark C. Field
Mark C. Field University of Dundee
Keith Gull
Keith Gull University of Oxford
Wendy Gibson
Wendy Gibson University of Bristol
Steven L. Kelly
Steven L. Kelly Swansea University
Susan C. Welburn
Susan C. Welburn University of Edinburgh
Etienne Pays
Etienne Pays Université Libre de Bruxelles
Christine Clayton
Christine Clayton Heidelberg University
Matthew Berriman
Matthew Berriman University of Glasgow
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Najib M. El-Sayed
Najib M. El-Sayed University of Maryland, College Park

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