World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
52
Citations
12852
World Ranking
3777
National Ranking
1628

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genome

His scientific interests lie mostly in Genetics, Gene, Genome, Genomic organization and Retrotransposon. His study in Trypanosoma brucei extends to Genome with its themes. His Trypanosoma brucei study incorporates themes from Subtelomere, Leishmania major, Pseudogene and Untranslated region.

His Genomic organization study integrates concerns from other disciplines, such as Expressed sequence tag, Genomic library, Complementary DNA, cDNA library and Peptide sequence. His Retrotransposon research incorporates themes from Whole genome sequencing, Mitochondrial DNA, Leishmania, Retroposon and Sequence analysis. His Synteny research is multidisciplinary, incorporating elements of Gene mapping, Caenorhabditis elegans, Wolbachia and Trypanosoma.

His most cited work include:

  • The Genome of the African Trypanosome Trypanosoma brucei (1391 citations)
  • The Genome of the African Trypanosome Trypanosoma brucei (1391 citations)
  • The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease (1143 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Genetics, Gene, Genome, Gene expression and Trypanosoma brucei. As part of his studies on Genetics, he often connects relevant areas like Molecular biology. His Gene study frequently draws connections between adjacent fields such as Trypanosoma cruzi.

His biological study spans a wide range of topics, including Regulation of gene expression, Messenger RNA and Antigen. His research integrates issues of Subtelomere, Phosphoglycerate kinase, Glycolysis, Phosphoglycerate mutase and Essential gene in his study of Trypanosoma brucei. His research in Genomic organization intersects with topics in cDNA library and Sequence analysis.

He most often published in these fields:

  • Genetics (65.74%)
  • Gene (56.48%)
  • Genome (44.44%)

What were the highlights of his more recent work (between 2017-2021)?

  • Microbiology (10.19%)
  • Transcriptome (12.04%)
  • Cell biology (12.04%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Microbiology, Transcriptome, Cell biology, Inflammation and Streptococcus. Najib M. El-Sayed interconnects Pseudomonas aeruginosa, Cystic fibrosis, Immune system and Virulence in the investigation of issues within Microbiology. His Transcriptome study combines topics in areas such as Molecular biology, Hsp70, Metallothionein, Trypanosoma cruzi and Gene silencing.

His study in Trypanosoma cruzi is interdisciplinary in nature, drawing from both RNA-binding protein, Messenger RNA, Gene expression and Gene. His study in the fields of STAT1 and Phosphorylation under the domain of Cell biology overlaps with other disciplines such as Tyrosine kinase 2 and Cell signaling. The subject of his Pathogen research is within the realm of Genetics.

Between 2017 and 2021, his most popular works were:

  • Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions (40 citations)
  • Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis. (27 citations)
  • Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides. (23 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genome

His main research concerns Microbiology, Immune system, Transferase, Antigen and CD8. Najib M. El-Sayed has included themes like Regulation of gene expression, Phosphoenolpyruvate carboxykinase, Metabolic pathway and Virulence in his Microbiology study. His work on Innate immune system as part of general Immune system research is frequently linked to Myeloid-derived Suppressor Cell, thereby connecting diverse disciplines of science.

His Transferase study combines topics from a wide range of disciplines, such as Polysaccharide, Carbohydrate and Bacteria. Najib M. El-Sayed has researched Antigen in several fields, including T cell, Leishmaniasis and Gene expression. His Biochemistry and Rhamnose and Cell wall investigations all form part of his Biochemistry research activities.

Best Publications

  • The Genome of the African Trypanosome Trypanosoma brucei

    Matthew Berriman;Elodie Ghedin;Elodie Ghedin;Christiane Hertz-Fowler;Gaelle Blandin

  • The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Daniella C. Bartholomeu;Daniel Nilsson

  • The genome of the blood fluke Schistosoma mansoni

    Matthew Berriman;Brian J. Haas;Brian J. Haas;Philip T. LoVerde;R. Alan Wilson

  • Comparative genomics of trypanosomatid parasitic protozoa.

    Najib M. El-Sayed;Peter J. Myler;Peter J. Myler;Gaëlle Blandin;Matthew Berriman

  • The genome of the protist parasite Entamoeba histolytica

    Brendan Loftus;Iain Anderson;Rob Davies;U. Cecilia M. Alsmark

  • Draft Genome of the Filarial Nematode Parasite Brugia malayi

    Elodie Ghedin;Elodie Ghedin;Shiliang Wang;David Spiro;Elisabet Caler

  • The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis.

    Jeff Quigley;V. Keith Hughitt;Carlos A. Velikovsky;Roy A. Mariuzza

  • Multiple mechanisms of immune evasion by African trypanosomes

    John E Donelson;Kent L Hill;Najib M.A El-Sayed

  • The African trypanosome genome.

    Najib M El-Sayed;Priti Hegde;John Quackenbush;Sara E Melville

  • Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection

    Yuan Li;Sheena Shah-Simpson;Kwame Okrah;A. Trey Belew

  • Genomic organization and expression profile of the mucin-associated surface protein (masp) family of the human pathogen Trypanosoma cruzi

    Daniella C. Bartholomeu;Gustavo C. Cerqueira;Ana Carolina A. Leão;Wanderson D. daRocha

  • Members of a Large Retroposon Family Are Determinants of Post-Transcriptional Gene Expression in Leishmania

    Frédéric Bringaud;Michaela Müller;Gustavo Coutinho Cerqueira;Martin Smith

  • cDNA expressed sequence tags of Trypanosoma brucei rhodesiense provide new insights into the biology of the parasite.

    Najib M.A. El-Sayed;Clara M. Alarcon;John C. Beck;Val C. Sheffield

  • Gene synteny and evolution of genome architecture in trypanosomatids

    Elodie Ghedin;Elodie Ghedin;Frederic Bringaud;Jeremy Peterson;Peter Myler

  • Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes.

    Yoann Le Breton;Ashton T. Belew;Kayla M. Valdes;Emrul Islam

  • Comparison of naturally acquired parasite burdens among Florida Native, Rambouillet and crossbreed ewes

    A.F.T Amarante;A.F.T Amarante;T.M Craig;W.S Ramsey;N.M El-Sayed;N.M El-Sayed

  • A new, expressed multigene family containing a hot spot for insertion of retroelements is associated with polymorphic subtelomeric regions of Trypanosoma brucei.

    Frédéric Bringaud;Nicolas Biteau;Sara E. Melville;Stéphanie Hez

  • Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region

    Scott J Westenberger;Gustavo C Cerqueira;Najib M El-Sayed;Bianca Zingales

  • Genetic nomenclature for Trypanosoma and Leishmania

    C Clayton;M Adams;R. Almeida;T Baltz

  • Schistosoma mansoni genome project: an update.

    Philip T LoVerde;Hirohisa Hirai;Joseph M Merrick;Norman H Lee

Frequent Co-Authors

Elodie Ghedin
Elodie Ghedin National Institutes of Health
Frédéric Bringaud
Frédéric Bringaud University of Bordeaux
Gustavo C. Cerqueira
Gustavo C. Cerqueira Broad Institute
David M. Mosser
David M. Mosser University of Maryland, College Park
Matthew Berriman
Matthew Berriman University of Glasgow
Neil Hall
Neil Hall Norwich Research Park
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Brian J. Haas
Brian J. Haas Broad Institute
Claire M. Fraser
Claire M. Fraser University of Maryland, Baltimore
Steven L. Salzberg
Steven L. Salzberg Johns Hopkins University

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