His primary scientific interests are in Immunology, Macrophage, Interleukin 10, Regulatory macrophages and Immune system. His Immunology research focuses on Receptor and how it connects with Phagocytosis. His study on Macrophage is mostly dedicated to connecting different topics, such as Cell biology.
His Interleukin 10 research is multidisciplinary, incorporating perspectives in Proinflammatory cytokine, Interleukin, Innate immune system and Monocyte. The study incorporates disciplines such as Histone H3, Autoimmunity and Interleukin 4 in addition to Regulatory macrophages. His work investigates the relationship between Immune system and topics such as Antibody that intersect with problems in Regulation of gene expression and Immunotherapy.
His main research concerns Immunology, Macrophage, Cell biology, Immune system and Inflammation. His Immunology research is multidisciplinary, incorporating elements of Receptor and Leishmania. In the field of Macrophage, his study on Regulatory macrophages overlaps with subjects such as Population.
His Cell biology study which covers Complement receptor that intersects with Microbiology, Factor H and Classical complement pathway. His biological study spans a wide range of topics, including Antibody and Antigen. His Inflammation research is multidisciplinary, relying on both Angiogenesis, Adenosine, Wound healing, Downregulation and upregulation and Immunity.
David M. Mosser mostly deals with Immunology, Cell biology, Immune system, Macrophage and Inflammation. His Immunology study frequently involves adjacent topics like Leishmania. His research in Cell biology tackles topics such as Complement membrane attack complex which are related to areas like NALP3, Innate immune system and Acquired immune system.
His Regulatory macrophages study, which is part of a larger body of work in Macrophage, is frequently linked to Population and Polarization, bridging the gap between disciplines. His research in Inflammation intersects with topics in Angiogenesis, Homeostasis, Wound healing, Downregulation and upregulation and Macrophage polarization. The concepts of his Macrophage polarization study are interwoven with issues in Macrophage colony-stimulating factor, Computational biology and Macrophage.
The scientist’s investigation covers issues in Immunology, Gene expression, Transcriptome, Cell biology and Immune system. His study brings together the fields of Macrophage colony-stimulating factor and Immunology. While the research belongs to areas of Gene expression, David M. Mosser spends his time largely on the problem of Leishmaniasis, intersecting his research to questions surrounding Antigen, CD8, T cell and Isotype.
His study looks at the relationship between Transcriptome and topics such as Gene expression profiling, which overlap with Leishmania major. His Cell biology study frequently links to related topics such as Macrophage. His Immune system research integrates issues from Microbiology and Leishmania.
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Exploring the full spectrum of macrophage activation.
David M. Mosser;Justin P. Edwards.
Nature Reviews Immunology (2008)
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Peter J Murray;Judith E Allen;Subhra K Biswas;Edward A Fisher.
Immunity (2014)
The many faces of macrophage activation
David M. Mosser.
Journal of Leukocyte Biology (2003)
The Isolation and Characterization of Murine Macrophages
Xia Zhang;Ricardo Goncalves;David M. Mosser.
Current protocols in immunology (2008)
Interleukin‐10: new perspectives on an old cytokine
David M. Mosser;Xia Zhang.
Immunological Reviews (2008)
Biochemical and functional characterization of three activated macrophage populations
Justin P. Edwards;Xia Zhang;Kenneth A. Frauwirth;David M. Mosser.
Journal of Leukocyte Biology (2006)
The Role of IL-10 in Promoting Disease Progression in Leishmaniasis
Margaret Mentink Kane;David M. Mosser.
Journal of Immunology (2001)
Macrophage activation by endogenous danger signals
X Zhang;DM Mosser.
The Journal of Pathology (2008)
Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis.
A Brittingham;C J Morrison;W R McMaster;B S McGwire.
Journal of Immunology (1995)
Selective Suppression of Interleukin-12 Induction after Macrophage Receptor Ligation
Fayyaz S. Sutterwala;Gary J. Noel;Raphael Clynes;David M. Mosser.
Journal of Experimental Medicine (1997)
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