Member of the Association of American Physicians
Lionel B. Ivashkiv mostly deals with Signal transduction, Cell biology, Cancer research, Inflammation and Immunology. His research in Signal transduction intersects with topics in Receptor and Chemokine receptor. His Cell biology research includes themes of Toll-like receptor, Autocrine signalling, Transcription factor, Molecular biology and Regulation of gene expression.
His Cancer research research integrates issues from Endocrinology, Internal medicine, Arthritis, Tissue homeostasis and STAT3. His Inflammation research integrates issues from Tumor necrosis factor alpha, Cytokine and STAT1. Much of his study explores Immunology relationship to Interleukin 12.
The scientist’s investigation covers issues in Cell biology, Immunology, Signal transduction, Cancer research and Cytokine. His research in Cell biology intersects with topics in Molecular biology, Regulation of gene expression, Transcription factor and Cellular differentiation. His Inflammation, Tumor necrosis factor alpha, Immune system, Proinflammatory cytokine and Innate immune system study are his primary interests in Immunology.
The Signal transduction study combines topics in areas such as Receptor, Autocrine signalling and Toll-like receptor. The concepts of his Cancer research study are interwoven with issues in Osteoclast, JAK-STAT signaling pathway, Bone resorption and Arthritis. His Cytokine study incorporates themes from SOCS3 and stat.
His primary areas of study are Cancer research, Cell biology, Immunology, Inflammation and Tumor necrosis factor alpha. His study in Cancer research is interdisciplinary in nature, drawing from both Cytokine, Bone resorption and Arthritis. Lionel B. Ivashkiv focuses mostly in the field of Cytokine, narrowing it down to matters related to Transcription factor and, in some cases, Downregulation and upregulation.
His Cell biology study combines topics from a wide range of disciplines, such as Enhancer, Regulation of gene expression, Histone and Proinflammatory cytokine. His Immunology research is multidisciplinary, relying on both Epigenomics, Osteoclast, Signal transduction and Epigenetics. His Inflammation research includes themes of Hypoxia and Homeostasis.
His primary areas of investigation include Arthritis, Cytokine, Fibroblast, Cancer research and Immunology. His research in Cancer research focuses on subjects like Tissue homeostasis, which are connected to Janus kinase, Immunosurveillance, Immune checkpoint, Cancer immunotherapy and Immunotherapy. His Immunology study combines topics in areas such as Epigenomics, Interleukin 12 and Signal transduction.
His Signal transduction research incorporates themes from Interferon, Immune tolerance, Innate immune system, Autoimmunity and Antigen presentation. His research integrates issues of Tumor necrosis factor alpha and Necroptosis in his study of Inflammation. His study looks at the relationship between Proinflammatory cytokine and topics such as Cell biology, which overlap with Lupus erythematosus.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Peter J Murray;Judith E Allen;Subhra K Biswas;Edward A Fisher.
Immunity (2014)
Regulation of type I interferon responses
Lionel B. Ivashkiv;Laura T. Donlin.
Nature Reviews Immunology (2014)
Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases
Xiaoyu Hu;Lionel B. Ivashkiv;Lionel B. Ivashkiv.
Immunity (2009)
TNF biology, pathogenic mechanisms and emerging therapeutic strategies
George D. Kalliolias;Lionel B. Ivashkiv.
Nature Reviews Rheumatology (2016)
IFN-γ Suppresses IL-10 Production and Synergizes with TLR2 by Regulating GSK3 and CREB/AP-1 Proteins
Xiaoyu Hu;Paul K. Paik;Janice Chen;Anna Yarilina.
Immunity (2006)
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
Deepak A. Rao;Michael F. Gurish;Jennifer L. Marshall;Kamil Slowikowski.
Nature (2017)
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes.
Anna Yarilina;Kyung-Hyun Park-Min;Taras Antoniv;Xiaoyu Hu.
Nature Immunology (2008)
Role of STAT3 in Type I Interferon Responses NEGATIVE REGULATION OF STAT1-DEPENDENT INFLAMMATORY GENE ACTIVATION
Hao H. Ho;Lionel B. Ivashkiv;Lionel B. Ivashkiv.
Journal of Biological Chemistry (2006)
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.
Haixia Xu;Jimmy Zhu;Sinead Smith;Julia Foldi.
Nature Immunology (2012)
mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element.
L. B. Ivashkiv;Hsiou-Chi Liou;C. J. Kara;W. W. Lamph.
Molecular and Cellular Biology (1990)
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