Lionel B. Ivashkiv

Research.com Recognitions

• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

  Peter J Murray;Judith E Allen;Subhra K Biswas;Edward A Fisher

  6527
  Citations

• Regulation of type I interferon responses

  Lionel B. Ivashkiv;Laura T. Donlin

  3544
  Citations

• TNF biology, pathogenic mechanisms and emerging therapeutic strategies

  George D. Kalliolias;Lionel B. Ivashkiv

  1466
  Citations

• IFNγ: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy.

  Lionel B. Ivashkiv;Lionel B. Ivashkiv

  1377
  Citations

• Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

  Deepak A. Rao;Michael F. Gurish;Jennifer L. Marshall;Kamil Slowikowski

  1118
  Citations

• Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases

  Xiaoyu Hu;Lionel B. Ivashkiv;Lionel B. Ivashkiv

  1053
  Citations

• Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

  Fumitaka Mizoguchi;Kamil Slowikowski;Kevin Wei;Jennifer L. Marshall

  582
  Citations

• Interferon target-gene expression and epigenomic signatures in health and disease

  Franck J. Barrat;Mary K. Crow;Mary K. Crow;Lionel B. Ivashkiv;Lionel B. Ivashkiv

  542
  Citations

• IFN-γ Suppresses IL-10 Production and Synergizes with TLR2 by Regulating GSK3 and CREB/AP-1 Proteins

  Xiaoyu Hu;Paul K. Paik;Janice Chen;Anna Yarilina

  514
  Citations

• TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes.

  Anna Yarilina;Kyung-Hyun Park-Min;Taras Antoniv;Xiaoyu Hu

  494
  Citations

• Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.

  Haixia Xu;Jimmy Zhu;Sinead Smith;Julia Foldi

  486
  Citations

• Epigenetic regulation of macrophage polarization and function.

  Lionel B. Ivashkiv

  469
  Citations

• Role of STAT3 in Type I Interferon Responses NEGATIVE REGULATION OF STAT1-DEPENDENT INFLAMMATORY GENE ACTIVATION

  Hao H. Ho;Lionel B. Ivashkiv;Lionel B. Ivashkiv

  411
  Citations

• Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation.

  William Stephenson;Laura T. Donlin;Andrew Butler;Cristina Rozo

  399
  Citations

• Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms.

  Xiaoyu Hu;Soumya D. Chakravarty;Lionel B. Ivashkiv;Lionel B. Ivashkiv

  363
  Citations

• Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

  Yu Qiao;Eugenia G. Giannopoulou;Chun Hin Chan;Sung-ho Park

  362
  Citations

• Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation.

  Xiaoyu Hu;Janice Chen;Lu Wang;Lionel B. Ivashkiv;Lionel B. Ivashkiv

  343
  Citations

• Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

  Xiaodi Su;Xiaodi Su;Yingpu Yu;Yi Zhong;Eugenia G Giannopoulou;Eugenia G Giannopoulou

  340
  Citations

• Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

  Baohong Zhao;Masamichi Takami;Atsushi Yamada;Xiaogu Wang

  333
  Citations

• Twist mediates suppression of inflammation by type I IFNs and Axl

  M. Nusrat Sharif;Dražen Šošić;Carla V. Rothlin;Erin Kelly

  332
  Citations

• mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element.

  L. B. Ivashkiv;Hsiou-Chi Liou;C. J. Kara;W. W. Lamph

  325
  Citations