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Menno P.J. de Winther

Menno P.J. de Winther

D-Index & Metrics

Immunology

D-Index
77
Citations
20283
World Ranking
1830
National Ranking
73

Overview

Menno P.J. de Winther is affiliated with the University of Amsterdam in the Netherlands. Their research spans several fields within the biomedical sciences, with a focus on immunology, microbiology, medicine, and molecular biology. The scientist's work includes contributions to subfields such as immunology, molecular biology, infectious diseases, surgery, and epidemiology.

The primary research topics addressed by Menno P.J. de Winther cover a broad range of biomedical interests. These include:

  • Atherosclerosis and cardiovascular diseases
  • Immune cells in cancer
  • Single-cell and spatial transcriptomics
  • Epigenetics and DNA methylation
  • T-cell and B-cell immunology
  • SARS-CoV-2 and COVID-19 research
  • Adipokines, inflammation, and metabolic diseases

Menno P.J. de Winther has contributed to multiple recent papers, several of which have been published in prominent journals. Notable publications include:

  • "Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics," 2020, Circulation Research
  • "Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity," 2020, Science
  • "High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages," 2021, Science Translational Medicine
  • "Macrophage subsets in atherosclerosis as defined by single-cell technologies," 2020, The Journal of Pathology
  • "Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition," 2020, Cell

The scientist frequently publishes in several journals and platforms, with particularly high contributions in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Atherosclerosis
  • Frontiers in Immunology
  • SSRN Electronic Journal
  • European Heart Journal

Menno P.J. de Winther collaborates with several coauthors in their research. Frequent collaborators include:

  • Koen H.M. Prange
  • Annette E. Neele
  • Guillermo R. Griffith
  • Johan Kuiper
  • Marie A.C. Depuydt

Best Publications

  • Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

    Nadine Jetten;Sanne Verbruggen;Marion J. Gijbels;Mark J. Post

  • Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

    Jan Van den Bossche;Jeroen Baardman;Natasja A. Otto;Saskia van der Velden

  • Nuclear factor kappaB signaling in atherogenesis

    Menno P.J. de Winther;Edwin Kanters;Georg Kraal;Marten H. Hofker

  • Distribution of macrophage polarization markers in human atherosclerosis

    J. Lauran Stöger;Marion J.J. Gijbels;Marion J.J. Gijbels;Saskia van der Velden;Marco Manca

  • Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease

    Betty S. van der Veen;Menno P. J. de Winther;Peter Heeringa

  • Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis.

    Ralph Gareus;Elena Kotsaki;Sofia Xanthoulea;Ingeborg van der Made

  • Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

    Edwin Kanters;Manolis Pasparakis;Marion J.J. Gijbels;Monique N. Vergouwe

  • Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity.

    Mads Delbo Larsen;Erik L. de Graaf;Myrthe E. Sonneveld;H. Rosina Plomp

  • Atherosclerotic Plaque Destabilization Mechanisms, Models, and Therapeutic Strategies

    Carlos Silvestre-Roig;Menno P. de Winther;Christian Weber;Mat J. Daemen

  • A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis.

    Eelke Brandsma;Niels J. Kloosterhuis;Mirjam Koster;Mirjam Koster;Daphne C. Dekker

  • Transcriptional and epigenetic regulation of macrophages in atherosclerosis.

    Tatyana Kuznetsova;Koen H. M. Prange;Christopher K. Glass;Menno P. J. de Winther;Menno P. J. de Winther

  • Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

    Esther Lutgens;Esther Lutgens;Dirk Lievens;Dirk Lievens;Linda Beckers;Erwin Wijnands

  • Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure

    Stephane Heymans;Maarten F. Corsten;Wouter Verhesen;Paolo Carai

  • Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis.

    Jan Van den Bossche;Jeroen Baardman;Menno P.J. de Winther

  • MicroRNA Profiling Identifies MicroRNA-155 as an Adverse Mediator of Cardiac Injury and Dysfunction During Acute Viral Myocarditis

    Maarten F Corsten;Anna-Pia Papageorgiou;Wouter Verhesen;Paolo Carai

  • Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

    Pieter Goossens;Marion J.J. Gijbels;Alma Zernecke;Wouter Eijgelaar

  • Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR−/− Mice

    Marcella van Leeuwen;Marion J. J. Gijbels;Adriaan Duijvestijn;Marjan Smook

  • High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages.

    Willianne Hoepel;Hung Jen Chen;Chiara E. Geyer;Sona Allahverdiyeva

  • Macrophage subsets in atherosclerosis as defined by single-cell technologies.

    Lisa Willemsen;Menno P. J. de Winther;Menno P. J. de Winther

  • PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia.

    Sophie J. Bernelot Moens;Annette E. Neele;Jeffrey Kroon;Fleur M. Van Der Valk

  • The class A macrophage scavenger receptor is a major pattern recognition receptor for Neisseria meningitidis which is independent of lipopolysaccharide and not required for secretory responses.

    Leanne Peiser;Menno P. J. de Winther;Katherine Makepeace;Michael Hollinshead

  • Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

    Anouk A.J. Hamers;Mariska Vos;Fadi Rassam;Goran Marinković

Frequent Co-Authors

Marion J.J. Gijbels
Marion J.J. Gijbels Maastricht University
Esther Lutgens
Esther Lutgens Ludwig-Maximilians-Universität München
Christian Weber
Christian Weber Ludwig-Maximilians-Universität München
Marten H. Hofker
Marten H. Hofker University Medical Center Groningen
Erik A.L. Biessen
Erik A.L. Biessen Maastricht University
Erik S.G. Stroes
Erik S.G. Stroes University of Amsterdam
Georg Kraal
Georg Kraal Vrije Universiteit Amsterdam
Oliver Soehnlein
Oliver Soehnlein University of Münster
Patrick C. N. Rensen
Patrick C. N. Rensen Leiden University Medical Center
Louis Boon
Louis Boon University of Amsterdam

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