The scientist’s investigation covers issues in Mutation, Genetics, Cancer research, DNA mismatch repair and Gene. Nickolas Papadopoulos interconnects Carcinogenesis, Telomere and Pathology in the investigation of issues within Mutation. His research integrates issues of Exome sequencing, Phenotype, Head and neck squamous-cell carcinoma, Tumor suppressor gene and Chromatin remodeling in his study of Cancer research.
His DNA mismatch repair study combines topics from a wide range of disciplines, such as Immune checkpoint, Blockade and Cell culture. His studies in Blockade integrate themes in fields like Pembrolizumab, T cell, Survival rate and Antigen. His Gene study combines topics in areas such as Cancer and DNA.
Nickolas Papadopoulos mainly investigates Cancer research, Cancer, Genetics, Internal medicine and Gene. The study incorporates disciplines such as Bladder cancer, T cell, KRAS and ATRX in addition to Cancer research. Mutation, Genome, DNA mismatch repair, Human genome and Germline mutation are the subjects of his Genetics studies.
His work deals with themes such as Carcinogenesis, Phenotype and Pathology, which intersect with Mutation. His DNA mismatch repair research is multidisciplinary, relying on both Blockade and Genetic testing. In his study, which falls under the umbrella issue of Internal medicine, Circulating tumor DNA is strongly linked to Oncology.
His main research concerns Internal medicine, Cancer, Cytokine storm, Cancer research and Molecular biology. His Internal medicine study frequently links to other fields, such as Oncology. He has researched Oncology in several fields, including Rectum and Colorectal cancer.
He does research in Cancer, focusing on KRAS specifically. His Cancer research research is multidisciplinary, incorporating perspectives in Cell, Cancer cell, Urinary system, Gene and Antibody. His Molecular biology research includes elements of Tumor antigen, Mutation and T-cell receptor.
Nickolas Papadopoulos mainly focuses on Cancer, Cytokine storm, Internal medicine, Antibody and Gene. Nickolas Papadopoulos incorporates Cancer and Extramural in his research. The various areas that Nickolas Papadopoulos examines in his Cytokine storm study include Inflammation, Immunology, Adrenergic receptor antagonists and Severe acute respiratory syndrome coronavirus 2.
His work often combines Internal medicine and Alpha-1 adrenergic receptor studies. His Antibody study combines topics from a wide range of disciplines, such as Cancer cell, T cell, Cancer research and Mutant. The study incorporates disciplines such as Cell, In vitro, Human leukocyte antigen and Phage display in addition to Gene.
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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
Dung T. Le;Jennifer N. Uram;Hao Wang;Bjarne R. Bartlett.
The New England Journal of Medicine (2015)
Cancer Genome Landscapes
Bert Vogelstein;Nickolas Papadopoulos;Victor E. Velculescu;Shibin Zhou.
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
Dung T. Le;Dung T. Le;Jennifer N. Durham;Jennifer N. Durham;Kellie N. Smith;Hao Wang.
Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
Siân Jones;Xiaosong Zhang;D. Williams Parsons;D. Williams Parsons;Jimmy Cheng Ho Lin.
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
Chetan Bettegowda;Chetan Bettegowda;Mark Sausen;Rebecca J. Leary;Isaac Kinde.
Science Translational Medicine (2014)
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
Fredrick S. Leach;Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu.
Mutation of a mutL homolog in hereditary colon cancer
Nickolas Papadopoulos;Nicholas C. Nicolaides;Ying Fei Wei;Steven M. Ruben.
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.
Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu;Ying Fei Weit.
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
Nishant Agrawal;Mitchell J. Frederick;Curtis R. Pickering;Chetan Bettegowda.
Daxx/atrx, men1, and mtor pathway genes are frequently altered in pancreatic neuroendocrine tumors
Yuchen Jiao;Chanjuan Shi;Barish H. Edil;Roeland F. De Wilde.
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