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2026

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Best Scientists

D-Index
250
Citations
350417
World Ranking
49
National Ranking
32

Medicine

D-Index
251
Citations
356587
World Ranking
32
National Ranking
23

Research.com Recognitions

  • 2026 - Research.com Medicine in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Medicine in United States Leader Award
  • 2022 - Research.com Biology and Biochemistry in United States Leader Award
  • 2019 - Fellow of the American Academy of Arts and Sciences
  • 2016 - Member of the National Academy of Sciences
  • 2015 - Member of the National Academy of Medicine (NAM)
  • 2015 - Fellow, National Academy of Inventors

Overview

Kenneth W. Kinzler is affiliated with Johns Hopkins University in the United States. Their research focuses extensively on medicine with substantial contributions in biochemistry, genetics, and molecular biology. Specific subfields include oncology, cancer research, molecular biology, radiology, nuclear medicine and imaging, as well as pathology and forensic medicine.

The scientist has contributed to several main topics of study, notably cancer genomics and diagnostics, monoclonal and polyclonal antibodies research, pancreatic and hepatic oncology research, genetic factors in colorectal cancer, CAR-T cell therapy research, immunotherapy and immune responses, and radiomics and machine learning in medical imaging.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology
  • Proceedings of the National Academy of Sciences
  • Nature
  • Nature Communications

Recent papers authored or co-authored by Kenneth W. Kinzler are:

  • Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer, 2022, New England Journal of Medicine
  • Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention, 2020, Science
  • Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers, 2021, Nature
  • Targeting a neoantigen derived from a common TP53 mutation, 2021, Science
  • Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study, 2021, PLoS Medicine

Their frequent co-authors include Bert Vogelstein, Nickolas Papadopoulos, Chetan Bettegowda, Shibin Zhou, and Maria Popoli.

Kenneth W. Kinzler has been recognized with several memberships and fellowships, such as:

  • Fellow of the American Academy of Arts and Sciences, 2019
  • Member of the National Academy of Sciences, 2016
  • Fellow, National Academy of Inventors, 2015
  • Member of the National Academy of Medicine (NAM), 2015

Best Publications

  • WAF1, a potential mediator of p53 tumor suppression

    Wafik S. El-Deiry;Takashi Tokino;Victor E. Velculescu;Daniel B. Levy

  • PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

    Dung T. Le;Jennifer N. Uram;Hao Wang;Bjarne R. Bartlett

  • Cancer Genome Landscapes

    Bert Vogelstein;Nickolas Papadopoulos;Victor E. Velculescu;Shibin Zhou

  • Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

    Dung T. Le;Dung T. Le;Jennifer N. Durham;Jennifer N. Durham;Kellie N. Smith;Hao Wang

  • An Integrated Genomic Analysis of Human Glioblastoma Multiforme

    D. Williams Parsons;Siân Jones;Xiaosong Zhang;Jimmy Cheng-Ho Lin

  • Lessons from Hereditary Colorectal Cancer

    Kenneth W Kinzler;Bert Vogelstein;Bert Vogelstein

  • Serial analysis of gene expression

    Kenneth W Kinzler;Victor E Velvulescu;Bert Vogelstein;Lin Zhang

  • IDH1 and IDH2 Mutations in Gliomas

    Hai Yan;D. Williams Parsons;Genglin Jin;Roger McLendon

  • Identification of c-MYC as a Target of the APC Pathway

    Tong Chuan He;Andrew B. Sparks;Carlo Rago;Heiko Hermeking

  • Cancer genes and the pathways they control.

    Bert Vogelstein;Kenneth W Kinzler

  • Genetic instabilities in human cancers

    Christoph Lengauer;Kenneth W. Kinzler;Bert Vogelstein

  • Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

    Patrice J. Morin;Andrew B. Sparks;Vladimir Korinek;Nick Barker

  • A simplified system for generating recombinant adenoviruses

    Tong-Chuan He;Bert Vogelstein;Kenneth W. Kinzler

  • Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

    Siân Jones;Xiaosong Zhang;D. Williams Parsons;D. Williams Parsons;Jimmy Cheng Ho Lin

  • Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

    Chetan Bettegowda;Chetan Bettegowda;Mark Sausen;Rebecca J. Leary;Isaac Kinde

  • Consensus coding sequences of human breast and colorectal cancers

    Tobias Sjoblom;Sian Jones;D. Williams Parsons;Laura D. Wood

  • High frequency of mutations of the PIK3CA gene in human cancers

    Yardena Samuels;Zhenghe Wang;Alberto Bardelli;Natalie Silliman

  • Genomic landscapes of human breast and colorectal cancers

    Laura D. Wood;Williams D. Parsons;Sian Jones;Jimmy Lin

  • Clues to the pathogenesis of familial colorectal cancer

    Lauri A. Aaltonen;Päivi Peltomäki;Fredrick S. Leach;Pertti Sistonen

  • Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies

    Chetan Bettegowda;Mark Sausen;Rebecca Leary;Isaac Kinde

Frequent Co-Authors

Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Nickolas Papadopoulos
Nickolas Papadopoulos Johns Hopkins University School of Medicine
Victor E. Velculescu
Victor E. Velculescu Johns Hopkins University School of Medicine
Luis A. Diaz
Luis A. Diaz Memorial Sloan Kettering Cancer Center
Ralph H. Hruban
Ralph H. Hruban Johns Hopkins University School of Medicine
Stanley R. Hamilton
Stanley R. Hamilton City Of Hope National Medical Center
Sanford D. Markowitz
Sanford D. Markowitz Case Western Reserve University
Christoph Lengauer
Christoph Lengauer Johns Hopkins University
Giovanni Parmigiani
Giovanni Parmigiani Harvard University
James K V Willson
James K V Willson The University of Texas at Dallas

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