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Medicine

D-Index
140
Citations
129579
World Ranking
1649
National Ranking
961

Overview

Luis A. Diaz is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on oncology and related subfields.

Their main subfields of study include:

  • Oncology
  • Pathology and Forensic Medicine
  • Cancer Research
  • Pulmonary and Respiratory Medicine
  • Genetics

The core topics of their research address various aspects of cancer biology and treatment, including:

  • Genetic factors in colorectal cancer
  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Treatments and Studies
  • Autoimmune Bullous Skin Diseases
  • Cancer Immunotherapy and Biomarkers
  • Pancreatic and Hepatic Oncology Research
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema

Luis A. Diaz has contributed to a significant number of research papers. Some recent notable publications include:

  • "Pembrolizumab in Microsatellite-Instability-High Advanced Colorectal Cancer," 2020, New England Journal of Medicine
  • "PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer," 2022, New England Journal of Medicine
  • "Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study," 2022, The Lancet Oncology
  • "Cancer therapy shapes the fitness landscape of clonal hematopoiesis," 2020, Nature Genetics
  • "Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406)," 2020, Journal of Clinical Oncology

They frequently collaborate with a range of co-authors, including:

  • Andrea Cercek
  • Michael F. Berger
  • Zsofia K. Stadler
  • Benoît Rousseau
  • Michael B. Foote

Their work has been published across several prominent venues, with notable numbers of publications in:

  • UNC Libraries
  • Journal of Clinical Oncology
  • Annals of Oncology
  • Cancer Research
  • New England Journal of Medicine

Best Publications

  • PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

    Dung T. Le;Jennifer N. Uram;Hao Wang;Bjarne R. Bartlett

  • Cancer Genome Landscapes

    Bert Vogelstein;Nickolas Papadopoulos;Victor E. Velculescu;Shibin Zhou

  • Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

    Dung T. Le;Dung T. Le;Jennifer N. Durham;Jennifer N. Durham;Kellie N. Smith;Hao Wang

  • An Integrated Genomic Analysis of Human Glioblastoma Multiforme

    D. Williams Parsons;Siân Jones;Xiaosong Zhang;Jimmy Cheng-Ho Lin

  • Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

    Chetan Bettegowda;Chetan Bettegowda;Mark Sausen;Rebecca J. Leary;Isaac Kinde

  • Circulating Mutant DNA to Assess Tumor Dynamics

    Frank Diehl;Luis Diaz;Kenneth W. Kinzler;Bert Vogelstein

  • Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 Study.

    Aurelien Marabelle;Dung T. Le;Paolo A. Ascierto;Anna Maria Di Giacomo

  • Detection and localization of surgically resectable cancers with a multi-analyte blood test

    Joshua D. Cohen;Lu Li;Yuxuan Wang;Christopher Thoburn

  • Liquid Biopsies: Genotyping Circulating Tumor DNA

    Luis A. Diaz;Alberto Bardelli

  • Fulminant Myocarditis with Combination Immune Checkpoint Blockade

    Douglas B. Johnson;Justin M. Balko;Margaret L. Compton;Spyridon Chalkias

  • Pembrolizumab in Microsatellite-Instability-High Advanced Colorectal Cancer.

    Thierry André;Kai-Keen Shiu;Tae Won Kim;Benny Vittrup Jensen

  • The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

    Luis A. Diaz;Luis A. Diaz;Richard T. Williams;Jian Wu;Jian Wu;Isaac Kinde

  • Daxx/atrx, men1, and mtor pathway genes are frequently altered in pancreatic neuroendocrine tumors

    Yuchen Jiao;Chanjuan Shi;Barish H. Edil;Roeland F. De Wilde

  • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

    Patrick J. Killela;Zachary J. Reitman;Yuchen Jiao;Chetan Bettegowda

  • Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

    Siân Jones;Tian Li Wang;Ie Ming Shih;Tsui Lien Mao

  • Detection and quantification of mutations in the plasma of patients with colorectal tumors.

    Frank Diehl;Meng Li;Devin Dressman;Yiping He

  • Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

    Jeanne Tie;Yuxuan Wang;Cristian Tomasetti;Cristian Tomasetti;Lu Li

  • Immunotherapy in colorectal cancer: rationale, challenges and potential.

    Karuna Ganesh;Zsofia K. Stadler;Andrea Cercek;Robin B. Mendelsohn

  • Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies

    Chetan Bettegowda;Mark Sausen;Rebecca Leary;Isaac Kinde

  • PD-1 blockade in tumors with mismatch repair deficiency.

    Dung T. Le;Jennifer N. Uram;Hao Wang;Bjarne Bartlett

Frequent Co-Authors

Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Kenneth W. Kinzler
Kenneth W. Kinzler Johns Hopkins University
Zhi Liu
Zhi Liu University of North Carolina at Chapel Hill
Victor E. Velculescu
Victor E. Velculescu Johns Hopkins University School of Medicine
Grant James Anhalt
Grant James Anhalt Johns Hopkins University
Nickolas Papadopoulos
Nickolas Papadopoulos Johns Hopkins University School of Medicine
George J. Giudice
George J. Giudice University of Iowa
Janet A. Fairley
Janet A. Fairley University of Iowa
Ralph H. Hruban
Ralph H. Hruban Johns Hopkins University School of Medicine
David B. Solit
David B. Solit Memorial Sloan Kettering Cancer Center

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